Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ONC held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 8.8M | $2.61B | 0.0% | 8.234% | 15.00% |
| 2 | PRIMECAP MANAGEMENT CO/CA/ | 5.0M | $1.48B | -0.1% | 4.656% | 1.16% |
| 3 | Capital International Investors | 4.2M | $1.23B | -18.7% | 3.892% | 0.29% |
| 4 | FMR LLC | 3.7M | $1.10B | -7.5% | 3.456% | 0.06% |
| 5 | Capital World Investors | 1.6M | $481.9M | — | 1.518% | 0.07% |
| 6 | CITADEL ADVISORS LLC | 1.1M | $312.6M | +88.8% | 0.985% | 0.15% |
| 7 | HHLR ADVISORS, LTD. | 1.0M | $307.2M | 0.0% | 0.968% | 18.36% |
| 8 | Temasek Holdings (Private) Ltd | 863K | $256.2M | -6.2% | 0.807% | 0.84% |
| 9 | BlackRock, Inc. | 658K | $195.3M | -2.8% | 0.615% | 0.00% |
| 10 | Siren, L.L.C. | 465K | $138.1M | -7.0% | 0.435% | 3.83% |
| 11 | MORGAN STANLEY | 464K | $137.9M | +6.1% | 0.435% | 0.01% |
| 12 | UBS Group AG | 415K | $123.3M | +173.1% | 0.389% | 0.02% |
| 13 | BANK OF AMERICA CORP /DE/ | 405K | $120.4M | +7.0% | 0.379% | 0.01% |
| 14 | Baird Financial Group, Inc. | 350K | $103.8M | +14.9% | 0.327% | 0.16% |
| 15 | CAPITAL INTERNATIONAL INC /CA/ | 302K | $89.8M | -1.8% | 0.283% | 0.69% |
| 16 | Candriam Luxembourg S.C.A. | 260K | $77.1M | +31.7% | 0.243% | 0.40% |
| 17 | Man Group plc | 242K | $71.8M | -2.6% | 0.226% | 0.13% |
| 18 | FIRST TRUST ADVISORS LP | 241K | $71.7M | +91.9% | 0.226% | 0.05% |
| 19 | MILLENNIUM MANAGEMENT LLC | 205K | $60.8M | — | 0.192% | 0.04% |
| 20 | FRANKLIN RESOURCES INC | 202K | $59.9M | +113.2% | 0.189% | 0.01% |
| 21 | Nuveen, LLC | 196K | $58.3M | +1.2% | 0.184% | 0.02% |
| 22 | BNP PARIBAS ARBITRAGE, SA | 184K | $54.7M | -5.0% | 0.172% | 0.03% |
| 23 | CAPITAL INTERNATIONAL SARL | 174K | $51.6M | +14.0% | 0.163% | 0.85% |
| 24 | MARSHALL WACE, LLP | 173K | $51.3M | +13.4% | 0.162% | 0.06% |
| 25 | DRIEHAUS CAPITAL MANAGEMENT LLC | 155K | $46.0M | +567.7% | 0.145% | 0.34% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in ONC — a direct measure of their conviction.
Filings activity in ONC during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 275 | 1.8% | 35.96% | +1.10 pp | $10.16B | +3.1% |
| Q4 2025 | 280 | +9.8% | 34.86% | 2.96 pp | $9.85B | 7.8% |
| Q3 2025 | 255 | +5.8% | 37.82% | +4.27 pp | $10.69B | +13% |
| Q2 2025 | 241 | 6.2% | 33.55% | 3.44 pp | $9.48B | 9.3% |
| Q1 2025 | 257 | +15% | 36.99% | +10.65 pp | $10.46B | +40% |
| Q4 2024 | 224 | +1.8% | 26.34% | 8.22 pp | $7.44B | 24% |
| Q3 2024 | 220 | +15% | 34.56% | +12.22 pp | $9.77B | +55% |
| Q2 2024 | 192 | — | 22.34% | — | $6.31B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ONC stock.
Based on Q1 2026 13F filings, institutional ownership of BeOne Medicines Ltd. stands at 36.0%, held across 275 reporting institutions.
BAKER BROS. ADVISORS LP is the largest reported institutional holder of ONC, with approximately 8,799,053 shares worth $2.61B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of ONC, including CITADEL ADVISORS LLC, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for ONC is 60 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
40 institutions opened new positions in ONC during Q1 2026, while 45 fully exited. 99 added to existing positions and 135 trimmed.
ONC institutional ownership rose by 1.10 percentage points quarter-over-quarter, with a net change of -5 holders.
The top 10 institutions account for 79.8% of all reported 13F value in ONC, and the top 25 account for 91.4%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
BeOne Medicines Ltd. (ONC) Institutional Ownership