Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in PLX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 3.6M | $7.8M | -0.8% | 4.489% | 0.00% |
| 2 | MAK CAPITAL ONE LLC | 3.5M | $7.7M | β | 4.399% | 1.13% |
| 3 | RENAISSANCE TECHNOLOGIES LLC | 1.2M | $2.7M | -3.0% | 1.520% | 0.00% |
| 4 | STATE STREET CORP | 973K | $2.1M | +66.2% | 1.207% | 0.00% |
| 5 | NORTHERN TRUST CORP | 885K | $1.9M | +2.3% | 1.099% | 0.00% |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 865K | $1.9M | +4.3% | 1.074% | 0.00% |
| 7 | Stratos Wealth Partners, LTD. | 500K | $1.1M | 0.0% | 0.621% | 0.01% |
| 8 | VANGUARD PORTFOLIO MANAGEMENT LLC | 432K | $938K | β | 0.537% | 0.00% |
| 9 | Prospera Financial Services Inc | 419K | $908K | β | 0.519% | 0.01% |
| 10 | Opaleye Management Inc. | 340K | $738K | -86.3% | 0.422% | 0.10% |
| 11 | MORGAN STANLEY | 302K | $655K | +128.7% | 0.375% | 0.00% |
| 12 | DIMENSIONAL FUND ADVISORS LP | 297K | $644K | +932.7% | 0.368% | 0.00% |
| 13 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 285K | $619K | +640.9% | 0.354% | 0.00% |
| 14 | UBS Group AG | 266K | $576K | +1.1% | 0.330% | 0.00% |
| 15 | GOLDMAN SACHS GROUP INC | 251K | $545K | -4.4% | 0.312% | 0.00% |
| 16 | Bank of New York Mellon Corp | 219K | $476K | +4.0% | 0.272% | 0.00% |
| 17 | Connor, Clark & Lunn Investment Management Ltd. | 207K | $450K | -10.7% | 0.257% | 0.00% |
| 18 | Round Rock Advisors, LLC | 192K | $417K | +23.8% | 0.238% | 0.06% |
| 19 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 189K | $410K | 0.0% | 0.235% | 0.01% |
| 20 | EVERGREEN CAPITAL MANAGEMENT LLC | 171K | $372K | 0.0% | 0.213% | 0.01% |
| 21 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 159K | $346K | -9.0% | 0.198% | 0.00% |
| 22 | Diametric Capital, LP | 124K | $270K | -10.6% | 0.154% | 0.07% |
| 23 | Nuveen, LLC | 90K | $196K | 0.0% | 0.112% | 0.00% |
| 24 | LAZARD ASSET MANAGEMENT LLC | 87K | $188K | +21.3% | 0.107% | 0.00% |
| 25 | BANK OF AMERICA CORP /DE/ | 79K | $172K | +70.6% | 0.098% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in PLX β a direct measure of their conviction.
Filings activity in PLX during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new PLX position in Q1 2026
Institutions that fully closed their PLX position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 96 | +17% | 21.50% | +6.06 pp | $36M | +39% |
| Q4 2025 | 82 | +7.9% | 15.44% | 2.71 pp | $26M | 15% |
| Q3 2025 | 76 | +19% | 18.15% | +7.92 pp | $31M | +77% |
| Q2 2025 | 64 | +1.6% | 10.23% | 2.05 pp | $17M | 17% |
| Q1 2025 | 63 | +37% | 12.28% | +7.93 pp | $21M | +182% |
| Q4 2024 | 46 | +4.5% | 4.35% | +2.65 pp | $7M | +156% |
| Q3 2024 | 44 | 31% | 1.70% | 2.50 pp | $3M | 60% |
| Q2 2024 | 64 | β | 4.20% | β | $7M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying PLX stock.
Based on Q1 2026 13F filings, institutional ownership of Protalix BioTherapeutics, Inc. stands at 21.5%, held across 96 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of PLX, with approximately 3,616,962 shares worth $0.01B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of PLX, including RENAISSANCE TECHNOLOGIES LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for PLX is 71 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
26 institutions opened new positions in PLX during Q1 2026, while 12 fully exited. 56 added to existing positions and 10 trimmed.
PLX institutional ownership rose by 6.06 percentage points quarter-over-quarter, with a net change of +14 holders.
The top 10 institutions account for 76.7% of all reported 13F value in PLX, and the top 25 account for 94.2%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Protalix BioTherapeutics, Inc. (PLX) Institutional Ownership