PRME trades 434.1% below Wall Street's consensus target of $17.25.
Last 12 months price action with 12-month analyst target path
The base valuation assumes PRME achieves its forward estimates and maintains a stable P/E multiple of historical averagesx. This scenario reflects the blended consensus of 9 Wall Street analysts, balancing both positive catalysts and macroeconomic headwinds over the next 12 months.
As of June 22, 2026, Prime Medicine, Inc. (PRME) has a Wall Street consensus price target of $17.25, based on estimates from 9 covering analysts. With the stock currently trading at $3.23, this represents a potential upside of +434.1%. The company has a market capitalization of $583M.
Analyst price targets range from a low of $12.00 to a high of $23.00, representing a 64% spread in expectations. The median target of $17.00 aligns closely with the consensus average. The wide target spread reflects significant disagreement on fair value.
The current analyst consensus rating is Buy, with 5 analysts rating the stock as a Buy or Strong Buy,4 rating it Hold, and 0 rating it Sell or Strong Sell. The positive sentiment balance indicates moderate optimism about the stock prospects.
From a valuation perspective, PRME trades at a trailing P/E of -2.4x. Analysts expect EPS to grow +10.8% over the next year.
| Company | Market Cap | Price | Target | Upside Potential | Rating | Fwd P/E | Analysts |
|---|---|---|---|---|---|---|---|
BEAMBeam Therapeutics Inc. | $3.5B | $34.14 | $48.00 | +40.6% | Buy | — | 27 |
CRSPCRISPR Therapeutics AG | $5.2B | $54.09 | $71.67 | +32.5% | Buy | — | 38 |
EDITEditas Medicine, Inc. | $263M | $2.69 | $5.00 | +85.9% | Buy | — | 25 |
NTLAIntellia Therapeutics, Inc. | $1.8B | $15.67 | $26.13 | +66.8% | Buy | — | 39 |
KRROKorro Bio, Inc. | $129M | $12.99 | $19.57 | +50.7% | Buy | — | 12 |
RCKTRocket Pharmaceuticals, Inc. | $366M | $3.35 | $5.00 | +49.3% | Buy | — | 19 |
SGMOSangamo Therapeutics, Inc. | $75M | $0.18 | $7.25 | +3927.8% | Hold | — | 14 |
ILMNIllumina, Inc. | $24.6B | $161.93 | $151.40 | -6.5% | Buy | 31.0x | 50 |
PACBPacific Biosciences of California, Inc. | $435M | $1.40 | $1.00 | -28.6% | Buy | — | 18 |
TWSTTwist Bioscience Corporation | $5.5B | $87.56 | $75.00 | -14.3% | Buy | — | 13 |
Quick answers to the most common questions about buying PRME stock.
The consensus Wall Street price target for PRME is $17.25, representing 434.1% upside from the current price of $3.23. With 9 analysts covering the stock, this strong upside suggests significant value not yet reflected in today's share price.
PRME has a consensus rating of "Buy" based on 9 Wall Street analysts. The rating breakdown is predominantly bullish, with 5 Buy/Strong Buy ratings. The consensus 12-month price target of $17.25 implies 434.1% upside from current levels.
PRME's current price is $3.23 with a consensus target of $17.25 (434.1% implied move). Analyst estimates suggest the stock is undervalued at current levels.
The most bullish Wall Street analyst has a price target of $23 for PRME, while the most conservative target is $12. The consensus of $17.25 represents the median expectation. These targets typically reflect 12-month expectations.
PRME is moderately covered, with 9 analysts providing price targets and ratings. Of these, 0 have Strong Buy ratings, 5 have Buy ratings, 4 recommend Hold, and 0 have Sell or Strong Sell ratings. Higher analyst coverage generally indicates greater institutional interest and more reliable consensus estimates.
The 12-month PRME stock forecast based on 9 Wall Street analysts shows a consensus price target of $17.25, with estimates ranging from $12 (bear case) to $23 (bull case). The median consensus rating is "Buy".
Wall Street analysts are very optimistic on PRME, with a "Buy" consensus rating and $17.25 price target (434.1% upside). 5 of 9 analysts rate it Buy or Strong Buy. This information is for educational purposes only. Always conduct your own research, consider your financial situation, and consult a financial advisor before making investment decisions.
PRME analyst price targets range from $12 to $23, a 64% wide spread indicating significant analyst disagreement. Differences stem from varying assumptions about revenue growth, profit margins, competitive dynamics, and valuation multiples. The $17.25 consensus represents the middle ground.
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