| 4 | SILVERARC CAPITAL MANAGEMENT, LLC | 2.9M | $22.6M | — | 8.986% | 2.35% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 2.6M | $19.8M | +133.5% | 7.876% | 0.00% |
| 6 | BVF INC/IL | 2.5M | $19.3M | — | 7.673% | 0.49% |
| 7 | Caligan Partners LP | 2.5M | $19.3M | — | 7.673% | 0.91% |
| 8 | Affinity Asset Advisors, LLC | 2.5M | $19.3M | +187.8% | 7.666% | 0.87% |
| 9 | FEDERATED HERMES, INC. | 2.1M | $16.1M | +267085.0% | 6.405% | 0.02% |
| 10 | GREAT POINT PARTNERS LLC | 2.0M | $15.7M | — | 6.230% | 2.97% |
| 11 | STATE STREET CORP | 2.0M | $15.4M | +1449.1% | 6.123% | 0.00% |
| 12 | Saturn V Capital Management LP | 1.5M | $11.4M | — | 4.542% | 1.64% |
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 1.4M | $11.2M | +366.5% | 4.432% | 0.00% |
| 14 | Blue Owl Capital Holdings LP | 1.3M | $9.7M | +277.6% | 3.869% | 1.47% |
| 15 | BAKER BROS. ADVISORS LP | 953K | $7.4M | 0.0% | 2.925% | 0.04% |
| 16 | MILLENNIUM MANAGEMENT LLC | 937K | $7.2M | +8.7% | 2.876% | 0.00% |
| 17 | Aberdeen Group plc | 848K | $6.6M | — | 2.602% | 0.01% |
| 18 | GOLDMAN SACHS GROUP INC | 759K | $5.9M | +348.5% | 2.330% | 0.00% |
| 19 | HHLR ADVISORS, LTD. | 725K | $5.6M | 0.0% | 2.225% | 0.67% |
| 20 | AMERIPRISE FINANCIAL INC | 581K | $4.5M | — | 1.784% | 0.00% |
| 21 | Vestal Point Capital, LP | 535K | $4.1M | — | 1.643% | 0.10% |
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 487K | $3.8M | +50.7% | 1.494% | 0.00% |
| 23 | NORTHERN TRUST CORP | 468K | $3.6M | +743.8% | 1.438% | 0.00% |
| 24 | BOOTHBAY FUND MANAGEMENT, LLC | 464K | $3.6M | — | 1.424% | 0.05% |
| 25 | ADAR1 Capital Management, LLC | 438K | $3.4M | — | 1.343% | 0.15% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in SGMT — a direct measure of their conviction.
| 70.02% |
| 15.93 pp |
| $44M |
| 41% |
| Q4 2024 | 66 | +4.8% | 85.95% | 8.41 pp | $75M | +49% |
| Q3 2024 | 63 | — | 94.36% | — | $50M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
57 institutions opened new positions in SGMT during Q2 2026, while 22 fully exited. 60 added to existing positions and 5 trimmed.
SGMT institutional ownership rose by 89.86 percentage points quarter-over-quarter, with a net change of +35 holders.
The top 10 institutions account for 58.8% of all reported 13F value in SGMT, and the top 25 account for 84.7%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.