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6May 4, 2026·SEC
Feb 17, 2026·SEC
Jan 12, 2026·SEC
Krystal Biotech, Inc. (KRYS) fundamental analysis — strengths, weaknesses & financial health based on data analysis
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Krystal Biotech, Inc. (KRYS) stock price & volume — 10-year historical chart
Krystal Biotech, Inc. (KRYS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Krystal Biotech, Inc. (KRYS) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q2 2026Latest | May 4, 2026 | $1.83vs $1.45+26.2% | $116Mvs $112M+3.8% |
| Q1 2026 | Feb 17, 2026 | $1.70vs $1.62+4.9% | $107Mvs $105M+1.7% |
| Q4 2025 | Nov 3, 2025 | $2.66vs $1.12+137.5% | $98Mvs $105M-7.1% |
| Q3 2025 | Aug 4, 2025 | $1.29vs $1.08+19.4% | $96Mvs $95M+0.7% |
Krystal Biotech, Inc. (KRYS) competitors in Cell and Gene Therapy Developers — business model, growth, and fundamentals comparison
Krystal Biotech, Inc. (KRYS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Krystal Biotech, Inc. (KRYS) annual income statement — 10-year revenue, gross profit & net income history
| Metric | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
Sales/Revenue | 0 | 1.03M | 0 | 0 | 0 | 0 | 50.7M | 290.51M | 389.13M | 417.3M |
Revenue Growth % | - | - | -100% | - | - | - | - | 473.02% | 33.94% | 25.15% |
Cost of Goods Sold | 23K | 141K | 974K | 1.85M | 0 | 0 | 3.09M | 20.06M | 28.77M | 30.07M |
COGS % of Revenue | - | 13.73% | - | - | - | - | 6.1% | 6.91% | 7.39% | - |
Gross Profit | -23K▲ 0% | 886K▲ 3952.2% | -974K▼ 209.9% | -1.85M▼ 90.0% | 0▲ 100.0% | 0▲ 0% | 47.6M▲ 0% | 270.45M▲ 468.1% | 360.36M▲ 33.2% | 387.24M▲ 0% |
Gross Margin % | - | 86.27% | - | - | - | - | 93.9% | 93.09% | 92.61% | 92.79% |
Gross Profit Growth % | -1050% | 3952.17% | -209.93% | -90.04% | 100% | - | - | 468.12% | 33.24% | - |
Operating Expenses | 4.77M | 11.92M | 22.08M | 31.15M | 68.28M | 145.2M | 157.33M | 204.76M | 199.06M | 208.43M |
OpEx % of Revenue | - | 1160.27% | - | - | - | - | 310.33% | 70.48% | 51.16% | - |
Selling, General & Admin | 1.56M | 4.16M | 6.46M | 13.21M | 40.39M | 77.73M | 98.4M | 113.69M | 146.74M | 155.03M |
SG&A % of Revenue | - | 404.58% | - | - | - | - | 194.09% | 39.13% | 37.71% | - |
Research & Development | 3.21M | 7.76M | 15.62M | 17.94M | 27.88M | 42.46M | 46.43M | 53.57M | 58.05M | 59.12M |
R&D % of Revenue | - | 755.7% | - | - | - | - | 91.58% | 18.44% | 14.92% | - |
Other Operating Expenses | 0 | 0 | 0 | 0 | 0 | 25M | 12.5M | 37.5M | -5.72M | -1000K |
Operating Income | -4.77M▲ 0% | -11.92M▼ 149.7% | -22.08M▼ 85.3% | -33M▼ 49.4% | -68.28M▼ 106.9% | -145.2M▼ 112.7% | -109.73M▲ 24.4% | 65.69M▲ 159.9% | 161.29M▲ 145.5% | 178.81M▲ 0% |
Operating Margin % | - | -1160.27% | - | - | - | - | -216.43% | 22.61% | 41.45% | 42.85% |
Operating Income Growth % | -317.5% | -149.71% | -85.31% | -49.45% | -106.9% | -112.66% | 24.43% | 159.87% | 145.52% | - |
EBITDA | -4.75M | -11.78M | -21.11M | -31.15M | -66.43M | -141.81M | -103.82M | 72.41M | 167.85M | 185.45M |
EBITDA Margin % | - | -1146.54% | - | - | - | - | -204.77% | 24.92% | 43.13% | 44.44% |
EBITDA Growth % | -316.21% | -147.95% | -79.25% | -47.57% | -113.26% | -113.49% | 26.79% | 169.75% | 131.8% | 60.85% |
D&A (Non-Cash Add-back) | 23K | 141K | 974K | 1.85M | 1.85M | 3.38M | 5.91M | 6.71M | 6.55M | 6.64M |
EBIT | -4.66M | -10.89M | -19.09M | -32.17M | -68.08M | -120.2M | -97.23M | 103.19M | 161.29M | 178.81M |
Net Interest Income | 0 | 0 | 2.99M | 832K | -1.29M | 5.22M | 22.62M | 29.66M | 28.18M | 0 |
Interest Income | 0 | 0 | 2.99M | 832K | 197K | 5.22M | 22.62M | 29.66M | 28.18M | 0 |
Interest Expense | 3.15M | 1.03M | 0 | 0 | 1.49M | 0 | 0 | 0 | 0 | 0 |
Other Income/Expense | -3.15M | 1.03M | 2.99M | 832K | -1.29M | 5.22M | 122.62M | 29.66M | 28.18M | 28.51M |
Pretax Income | -7.92M▲ 0% | -10.89M▼ 37.5% | -19.09M▼ 75.3% | -32.17M▼ 68.5% | -69.57M▼ 116.3% | -139.97M▼ 101.2% | 12.9M▲ 109.2% | 95.36M▲ 639.4% | 189.47M▲ 98.7% | 207.32M▲ 0% |
Pretax Margin % | - | -1060.27% | - | - | - | - | 25.44% | 32.82% | 48.69% | 49.68% |
Income Tax | 0 | -20.14K | 0 | 0 | 0 | 0 | 1.97M | 6.2M | -15.36M | -17.71M |
Effective Tax Rate % | 0% | 0.18% | 0% | 0% | 0% | 0% | 15.24% | 6.5% | -8.11% | -8.54% |
Net Income | -7.92M▲ 0% | -10.89M▼ 37.5% | -19.09M▼ 75.3% | -32.17M▼ 68.5% | -69.57M▼ 116.3% | -139.97M▼ 101.2% | 10.93M▲ 107.8% | 89.16M▲ 715.6% | 204.83M▲ 129.7% | 225.03M▲ 0% |
Net Margin % | - | -1060.27% | - | - | - | - | 21.56% | 30.69% | 52.64% | 53.92% |
Net Income Growth % | -588.7% | -37.49% | -75.3% | -68.52% | -116.28% | -101.2% | 107.81% | 715.58% | 129.74% | 81.53% |
Net Income (Continuing) | -7.92M | -10.89M | -19.09M | -32.17M | -69.57M | -139.97M | 10.93M | 89.16M | 204.83M | 225.03M |
Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
EPS (Diluted) | -1.48▲ 0% | -0.97▲ 34.5% | -1.20▼ 23.7% | -1.71▼ 42.5% | -3.13▼ 83.0% | -5.49▼ 75.4% | 0.39▲ 107.1% | 3.00▲ 669.2% | 6.84▲ 128.0% | 7.38▲ 0% |
EPS Growth % | -448.15% | 34.46% | -23.71% | -42.5% | -83.04% | -75.4% | 107.1% | 669.23% | 128% | 79.81% |
EPS (Basic) | -1.48 | -0.97 | -1.20 | -1.71 | -3.13 | -5.49 | 0.40 | 3.12 | 7.08 | - |
Diluted Shares Outstanding | 5.36M | 11.2M | 15.9M | 18.79M | 22.2M | 25.49M | 27.75M | 29.74M | 29.95M | 30.51M |
Basic Shares Outstanding | 5.36M | 11.2M | 15.9M | 18.79M | 22.2M | 25.49M | 27.15M | 28.59M | 28.94M | 29.29M |
Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - |
Krystal Biotech, Inc. (KRYS) balance sheet — assets, liabilities & shareholders' equity
| Metric | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
Total Current Assets | 49.91M | 112.65M | 195.88M | 275.06M | 442.27M | 383.78M | 587.91M | 742.04M | 1.02B | 1.02B |
Cash & Short-Term Investments | 49.59M | 111.76M | 193.69M | 271.26M | 438.1M | 379.17M | 532.18M | 597.52M | 827.79M | 823.4M |
Cash Only | 49.59M | 103.67M | 187.51M | 268.27M | 341.25M | 161.9M | 358.33M | 344.87M | 496.3M | 501.31M |
Short-Term Investments | 0 | 8.09M | 6.17M | 2.99M | 96.85M | 217.27M | 173.85M | 252.65M | 331.49M | 322.09M |
Accounts Receivable | 0 | 0 | 0 | 0 | 0 | 0 | 42.04M | 104.75M | 127.42M | 127.02M |
Days Sales Outstanding | - | - | - | - | - | - | 302.66 | 131.6 | 119.52 | 108.35 |
Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 6.99M | 26.51M | 40.48M | 42.65M |
Days Inventory Outstanding | - | - | - | - | - | - | 824.02 | 482.3 | 513.45 | 460.66 |
Other Current Assets | 0 | 0 | 0 | 0 | 0 | 4.61M | 6.71M | 13.27M | 28.91M | 26.67M |
Total Non-Current Assets | 200K | 3.47M | 13.14M | 35.79M | 184.03M | 174.67M | 230.45M | 313.79M | 309.19M | 377.23M |
Property, Plant & Equipment | 200K | 3.01M | 11.18M | 34.17M | 119.58M | 169.73M | 168.23M | 161.45M | 158.01M | 160.62M |
Fixed Asset Turnover | - | 0.34x | - | - | - | - | 0.30x | 1.80x | 2.46x | 2.64x |
Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-Term Investments | 0 | 0 | 497K | 0 | 64.37M | 4.62M | 61.95M | 152.11M | 128.07M | 593.47M |
Other Non-Current Assets | 0 | 452K | 1.46M | 1.61M | 74K | 324K | 263K | 231K | 287K | 300K |
Total Assets | 50.11M▲ 0% | 116.12M▲ 131.7% | 209.02M▲ 80.0% | 310.84M▲ 48.7% | 626.29M▲ 101.5% | 558.45M▼ 10.8% | 818.36M▲ 46.5% | 1.06B▲ 29.0% | 1.33B▲ 26.3% | 1.4B▲ 0% |
Asset Turnover | - | 0.01x | - | - | - | - | 0.06x | 0.28x | 0.29x | 0.33x |
Asset Growth % | 2196.7% | 131.7% | 80.01% | 48.71% | 101.48% | -10.83% | 46.54% | 29.02% | 26.33% | 106.64% |
Total Current Liabilities | 640K | 2.6M | 3.33M | 15.45M | 25.74M | 28.85M | 33.09M | 102M | 102.94M | 107.8M |
Accounts Payable | 193K | 888K | 1.02M | 2.1M | 8.4M | 3.98M | 1.85M | 4.99M | 3.24M | 4.09M |
Days Payables Outstanding | 3.06K | 2.3K | 382.61 | 415.09 | - | - | 218.13 | 90.7 | 41.08 | 50.22 |
Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.8M |
Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Other Current Liabilities | 437K | 1.36M | 12K | 26K | 87K | 267K | 16.75M | 2.4M | 97.93M | 101.91M |
Current Ratio | 77.99x | 43.39x | 58.88x | 17.80x | 17.18x | 13.30x | 17.76x | 7.28x | 9.95x | 9.46x |
Quick Ratio | 77.99x | 43.39x | 58.88x | 17.80x | 17.18x | 13.30x | 17.55x | 7.02x | 9.56x | 9.06x |
Cash Conversion Cycle | - | - | - | - | - | - | 908.56 | 523.2 | 591.89 | 518.8 |
Total Non-Current Liabilities | 0 | 294K | 2.78M | 3.31M | 6.98M | 7.37M | 6.62M | 7.46M | 11.29M | 12.44M |
Long-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Capital Lease Obligations | 0 | 0 | 2.78M | 3.31M | 6.98M | 7.37M | 6.62M | 6.04M | 7.57M | 23.45M |
Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Other Non-Current Liabilities | 0 | 294K | 0 | 0 | 0 | 0 | 0 | 1.42M | 3.72M | 12.44M |
Total Liabilities | 640K | 2.89M | 6.11M | 18.76M | 32.72M | 36.22M | 39.71M | 109.46M | 114.23M | 120.24M |
Total Debt | 0 | 0 | 3.26M | 11.55M | 8.02M | 8.93M | 8.09M | 7.26M | 9.34M | 1.8M |
Net Debt | -49.59M | -103.67M | -184.25M | -256.72M | -333.22M | -152.97M | -350.23M | -337.6M | -486.96M | -499.51M |
Debt / Equity | - | - | 0.02x | 0.04x | 0.01x | 0.02x | 0.01x | 0.01x | 0.01x | 0.00x |
Debt / EBITDA | - | - | - | - | - | - | - | 0.10x | 0.06x | 0.01x |
Net Debt / EBITDA | - | - | - | - | - | - | - | -4.66x | -2.90x | -2.69x |
Interest Coverage | -1.48x | -10.60x | - | - | -45.63x | - | - | - | - | - |
Total Equity | 49.47M▲ 0% | 113.23M▲ 128.9% | 202.91M▲ 79.2% | 292.08M▲ 43.9% | 593.58M▲ 103.2% | 522.23M▼ 12.0% | 778.64M▲ 49.1% | 946.38M▲ 21.5% | 1.22B▲ 28.9% | 1.28B▲ 0% |
Equity Growth % | 17019.03% | 128.86% | 79.21% | 43.94% | 103.22% | -12.02% | 49.1% | 21.54% | 28.87% | 111.03% |
Book Value per Share | 9.23 | 10.11 | 12.76 | 15.55 | 26.74 | 20.49 | 28.06 | 31.82 | 40.72 | 41.85 |
Total Shareholders' Equity | 49.47M | 113.23M | 202.91M | 292.08M | 593.58M | 522.23M | 778.64M | 946.38M | 1.22B | 1.28B |
Common Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retained Earnings | -9.07M | -19.96M | -39.05M | -71.21M | -140.78M | -280.76M | -269.83M | -180.67M | 24.16M | 80.09M |
Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accumulated OCI | -25K | 2K | 10K | 6K | -163K | -728K | 638K | -190K | 1.14M | -1.62M |
Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Krystal Biotech, Inc. (KRYS) cash flow — operating, investing & free cash flow history
| Metric | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
Cash from Operations | -3.89M | -9.45M | -18.71M | -26.08M | -47.94M | -100.57M | -88.8M | 123.42M | 200.87M | 250.28M |
Operating CF Margin % | - | -919.67% | - | - | - | - | -175.16% | 42.48% | 51.62% | - |
Operating CF Growth % | -196.72% | -142.8% | -98.13% | -39.38% | -83.79% | -109.79% | 11.7% | 238.98% | 62.75% | 1538.71% |
Net Income | -7.92M | -10.89M | -19.09M | -32.17M | -69.57M | -139.97M | 10.93M | 89.16M | 204.83M | 225.03M |
Depreciation & Amortization | 23K | 141K | 748K | 1.85M | 2.77M | 4.05M | 5.01M | 6.71M | 6.55M | 6.44M |
Stock-Based Compensation | 246K | 792K | 1.24M | 3.27M | 15.32M | 33.23M | 39.93M | 49.13M | 54.51M | 27.73M |
Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -22.84M | -22.84M |
Other Non-Cash Items | 3.26M | 962K | 67K | 33K | 1.49M | -690K | -106.79M | -7.12M | -5.77M | 17.8M |
Working Capital Changes | 498K | 511K | -1.68M | 928K | 2.05M | 2.81M | -37.88M | -14.46M | -36.42M | -3.87M |
Change in Receivables | 0 | 0 | 0 | 0 | 0 | 0 | -42.04M | -62.71M | -22.12M | -23.55M |
Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | -4.47M | -11.91M | -6.29M | -5.13M |
Change in Payables | 133K | 112K | -199K | 783K | 712K | -1.25M | -101K | 1.01M | 826K | 942K |
Cash from Investing | -210K | -10.32M | -4.97M | -11.18M | -226.77M | -114.08M | 82.64M | -163.44M | -58.42M | -67.23M |
Capital Expenditures | -210K | -2.23M | -6.4M | -14.84M | -68.34M | -52.98M | -11.8M | -4.24M | -11.95M | -12.89M |
CapEx % of Revenue | - | 217.53% | - | - | - | - | 23.27% | 1.46% | 3.07% | 3.09% |
Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 435K | 0 |
Investments | - | - | - | - | - | - | - | - | - | - |
Other Investing | 0 | 0 | 0 | 0 | 0 | 0 | 100M | 0 | 0 | 0 |
Cash from Financing | 51.77M | 73.85M | 107.53M | 118.02M | 347.69M | 35.35M | 202.75M | 27.01M | 8.71M | 10.71M |
Debt Issued (Net) | 2.3M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Equity Issued (Net) | 49.47M | 73.85M | 107.53M | 118.02M | 355.64M | 36M | 203.5M | 32.4M | 22.66M | 10.74M |
Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -16.96M |
Other Financing | 0 | 0 | 0 | 0 | -7.96M | -649K | -749K | -5.39M | -13.96M | -28K |
Net Change in Cash | 47.67M▲ 0% | 54.08M▲ 13.4% | 83.84M▲ 55.0% | 80.75M▼ 3.7% | 72.98M▼ 9.6% | -179.35M▼ 345.8% | 196.43M▲ 209.5% | -13.46M▼ 106.9% | 151.44M▲ 1224.9% | 192.54M▲ 0% |
Free Cash Flow | -4.1M▲ 0% | -11.68M▼ 184.9% | -25.11M▼ 115.0% | -40.93M▼ 63.0% | -116.27M▼ 184.1% | -153.55M▼ 32.1% | -100.6M▲ 34.5% | 119.18M▲ 218.5% | 188.91M▲ 58.5% | 237.38M▲ 0% |
FCF Margin % | - | -1137.2% | - | - | - | - | -198.43% | 41.02% | 48.55% | 56.88% |
FCF Growth % | -209.2% | -184.85% | -115.02% | -62.97% | -184.11% | -32.06% | 34.48% | 218.47% | 58.51% | 83.56% |
FCF per Share | -0.76 | -1.04 | -1.58 | -2.18 | -5.24 | -6.02 | -3.63 | 4.01 | 6.31 | 7.78 |
FCF Conversion (FCF/Net Income) | 0.49x | 0.87x | 0.98x | 0.81x | 0.69x | 0.72x | -8.12x | 1.38x | 0.98x | 1.05x |
Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.67M | 0 | 13.48M |
Krystal Biotech, Inc. (KRYS) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
Return on Equity (ROE) | -31.83% | -13.39% | -12.08% | -13% | -15.71% | -25.09% | 1.68% | 10.34% | 18.91% | 19.25% |
Return on Invested Capital (ROIC) | -7780.43% | -189.36% | -117.38% | -91.62% | -34.63% | -34.59% | -20.63% | 9.5% | 18.04% | 18.12% |
Gross Margin | - | 86.27% | - | - | - | - | 93.9% | 93.09% | 92.61% | 92.79% |
Net Margin | - | -1060.27% | - | - | - | - | 21.56% | 30.69% | 52.64% | 53.92% |
Debt / Equity | - | - | 0.02x | 0.04x | 0.01x | 0.02x | 0.01x | 0.01x | 0.01x | 0.00x |
Interest Coverage | -1.48x | -10.60x | - | - | -45.63x | - | - | - | - | - |
FCF Conversion | 0.49x | 0.87x | 0.98x | 0.81x | 0.69x | 0.72x | -8.12x | 1.38x | 0.98x | 1.05x |
Revenue Growth | - | - | -100% | - | - | - | - | 473.02% | 33.94% | 25.15% |
Krystal Biotech, Inc. (KRYS) SEC filings — annual & quarterly reports (10-K, 10-Q)
May 4, 2026·SEC
Feb 17, 2026·SEC
Jan 12, 2026·SEC
Krystal Biotech, Inc. (KRYS) stock FAQ — growth, dividends, profitability & financials explained
Krystal Biotech, Inc. (KRYS) reported $417.3M in revenue for fiscal year 2025.
Krystal Biotech, Inc. (KRYS) grew revenue by 33.9% over the past year. This is strong growth.
Yes, Krystal Biotech, Inc. (KRYS) is profitable, generating $225.0M in net income for fiscal year 2025 (52.6% net margin).
Krystal Biotech, Inc. (KRYS) has a return on equity (ROE) of 18.9%. This is reasonable for most industries.
Krystal Biotech, Inc. (KRYS) generated $237.4M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.