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KRYS
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KRYSKrystal Biotech, Inc.
$300.88$8.9B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
Live BreakoutsStock ScreenerOwnership
KRYS logo

Krystal Biotech, Inc.

KRYS
NASDAQ · Cell & Gene Therapy
$300.88
At close - Nov 6, 4:00 PM EST - USD
Market Cap$8.87B
P/E41.2x
52W High$382.54
Volume234.16K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q3

Near-90% Gross Margins Meet Decelerating Single-Product Growth

Krystal Biotech's revenue rose from $70.3M in 2024Q2 to $127.3M in 2026Q3 with gross margins holding between 89.8% and 94.6%, and free cash flow margin reached 70.9% in the latest quarter, indicating the VYJUVEK commercial base has crossed a durable profitability threshold.

GrowthDecelerating
ProfitabilityStrong
ValuationExpensive
TechnicalsWeak
Explore valuation models
MARKET ACTION

KRYS price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

10/12 Beats

EPS beat 10 of last 12 quarters

02

Valuation risk

+42% Peers

P/E is 42% above peer median

03

Market leadership

RS 53 · Avg

Average momentum (RS Rating: 53)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Feb 2
01

Build the investment case

Start with the evidence for owning the stock and the risks that can break the thesis.

EXECUTIVE THESIS

The Investment Case

Full Analysis
Fundamental Trajectory

Revenue reached $127.3M in 2026Q3 with operating margin expanding from 12.2% in 2024Q2 to 55.9%, though year-over-year growth has slowed from 94.9% to 30.2%, warranting close monitoring.

Analyst Consensus+39.3% target
Buy(18 analysts)
18 Buy0 Hold0 Sell

The Bull Case

Upside Catalysts

Strong revenue growth forecast

Forecasting 45% revenue growth to $564M in 2026, indicating robust business expansion.

High margin scalability

94% gross margin TTM with 42% operating margin demonstrates a highly scalable gene therapy platform.

Undervalued stock potential

Bull case fair value estimated at $315 per share, suggesting ~5.8% undervaluation vs. recent close.

The Bear Case

Key Downside Risks

Market performance

Price History →

Trailing total returns as of 11/7/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
KRYS+21.86%
S&P 500 (^GSPC)+7.63%
1-Year Return
KRYS+50.46%
S&P 500 (^GSPC)+9.69%
3-Year Return
KRYS+189.95%
S&P 500 (^GSPC)+69.19%
5-Year Return
KRYS+512.91%
S&P 500 (^GSPC)+57.23%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/EMedian
41.2x
Forward P/EExpansion
39.2x
EV/EBITDA0th %ile
35.8x
FCF YieldCash Flow
3.5%

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
41.2x
52.2x
33rd· Fair
EV/EBITDA
35.8x
59.7x
0th· Low
Price/FCF
28.6x
39.1x
0th· Low
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$119.85-60.2%
Base (Fair)$206.87-31.2%
Bull$229.43-23.7%
$119.85 Bear$206.87 Base$229.43 Bull
Current Market Price: $300.88
Trades at a 45.4% premium to Base DCF ($206.87)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$389M+33.9% YoY
Net income FY25
$205M+129.7% YoY
Free cash flow FY25
$189M+58.5% YoY
Operating margin FY25
41.5%+18.8 pts YoY
ROIC (FY25)18%
Avg ROIC 5Y-12.5%
ROE (TTM)17%
Piotroski Score5 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate10/12 (83%)
Revenue Beat Rate6/12 (50%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 2, 2026
$2.05+14.5%
vs $1.79
$127M+1.2%
vs $126M
Q3 2026
Aug 3, 2026
$1.79+5.3%
vs $1.70
$119M-1.4%
vs $121M
Q2 2026
May 4, 2026
$1.83+26.2%
vs $1.45
$116M+3.8%
vs $112M
Q1 2026
Feb 17, 2026
$1.70+4.9%
vs $1.62
$107M+1.7%
vs $105M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Benzinga·5d ago
Krystal Biotech Analyst Says Stock Weakness 'Overblown'

Krystal Biotech Inc. (NASDAQ:KRYS) stock is trading lower on Monday after the company provided a third-quarter update.

Seeking Alpha·5d ago
Krystal Biotech, Inc. (KRYS) Q3 2026 Earnings Call Transcript

Krystal Biotech, Inc. (KRYS) Q3 2026 Earnings Call Transcript

Zacks Investment Research·5d ago
Krystal Biotech, Inc. (KRYS) Surpasses Q3 Earnings and Revenue Estimates

Krystal Biotech, Inc. (KRYS) came out with quarterly earnings of $2.05 per share, beating the Zacks Consensus Estimate of $1.84 per share. This compares to earnings of $2.66 per share a year ago.

Schaeffers Research·5d ago
Nasdaq Rallies as Tech Stocks Recover From Friday's Selloff

Stocks are higher midday as tech stocks bounce back as peace-talk hopes grew while fanning oil prices

Filtered for Krystal Biotech, Inc.More Headlines
04

Compare before deciding

Benchmark KRYS against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Krystal Biotech, Inc. (KRYS)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
KRYS logoKRYSKrystal Biotech, Inc.Current
$300.88$8.87B41.2133.94%47.91%17.02%—
RCKT logoRCKTRocket Pharmaceuticals, Inc.
$2.38$259.88M-15.80——-5.76%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$15.43$1.52B-3.0120.13%-71.78%——
ACAD logoACADACADIA Pharmaceuticals Inc.
$21.23$3.64B10.2811.87%30.13%28.03%—
PTCT logoPTCTPTC Therapeutics, Inc.
$65.44$5.43B-51.55114.51%-9.17%——
SRPT logoSRPTSarepta Therapeutics, Inc.
$17.82$1.88B127.9315.58%0.75%1.04%—

Compare KRYS vs Peers

Krystal Biotech, Inc. (KRYS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RCKT

Most directly comparable listed peer for KRYS.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare KRYS against a more recognizable public peer.

Peer Set

Compare Top 5

vs RCKT, RARE, ACAD, PTCT

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

KRYS SEC Filings & Documents

Krystal Biotech, Inc. (KRYS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Nov 2, 2026·SEC

Material company update

Oct 15, 2026·SEC

Material company update

Aug 3, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 17, 2026·SEC

FY 2025

Feb 19, 2025·SEC

FY 2024

Feb 26, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Nov 2, 2026·SEC

FY 2026

Aug 3, 2026·SEC

FY 2026

May 4, 2026·SEC

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KRYS Frequently Asked Questions

Krystal Biotech, Inc. (KRYS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Krystal Biotech, Inc.'s revenue?

Krystal Biotech, Inc. (KRYS) reported $470.0M in revenue over the trailing twelve months. Revenue was $389.1M in fiscal year 2025.

How fast is Krystal Biotech, Inc. growing?

Krystal Biotech, Inc. (KRYS) grew revenue by 26.0% over the trailing twelve months, compared with the twelve months before.

Is KRYS profitable?

Yes. Krystal Biotech, Inc. (KRYS) earned $225.2M in net income over the trailing twelve months (a 47.9% net margin).

Dividend & Returns
What is KRYS's return on equity?

Krystal Biotech, Inc. (KRYS) had a return on equity (ROE) of 17.0% over the trailing twelve months. That is above the market's typical 10-15%.

What is Krystal Biotech, Inc.'s free cash flow?

Krystal Biotech, Inc. (KRYS) generated $310.1M in free cash flow over the trailing twelve months.

What if you invested $1,000 in KRYS back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →