Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in SMMT held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 32.8M | $477.7M | -9.9% | 4.110% | 2.39% |
| 2 | FMR LLC | 10.0M | $146.3M | -7.5% | 1.259% | 0.01% |
| 3 | STATE STREET CORP | 9.5M | $139.0M | +35.7% | 1.196% | 0.00% |
| 4 | BlackRock, Inc. | 9.5M | $138.8M | -1.3% | 1.195% | 0.00% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 5.7M | $83.6M | +0.4% | 0.719% | 0.00% |
| 6 | UBS Group AG | 5.3M | $77.3M | +43.4% | 0.665% | 0.01% |
| 7 | VANGUARD PORTFOLIO MANAGEMENT LLC | 5.0M | $73.5M | -3.6% | 0.632% | 0.00% |
| 8 | GOLDMAN SACHS GROUP INC | 4.5M | $65.8M | +1352.5% | 0.566% | 0.01% |
| 9 | Point72 Asset Management, L.P. | 3.7M | $53.9M | +361.6% | 0.464% | 0.06% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 3.4M | $50.0M | +3.4% | 0.430% | 0.00% |
| 11 | CITADEL ADVISORS LLC | 2.9M | $41.9M | +171.0% | 0.360% | 0.00% |
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2.4M | $35.0M | -0.4% | 0.301% | 0.00% |
| 13 | MILLENNIUM MANAGEMENT LLC | 2.3M | $34.2M | +1760.3% | 0.295% | 0.01% |
| 14 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 2.0M | $29.0M | β | 0.249% | 0.04% |
| 15 | BALYASNY ASSET MANAGEMENT L.P. | 1.9M | $27.7M | +247.3% | 0.239% | 0.03% |
| 16 | Squarepoint Ops LLC | 1.8M | $26.7M | +198.4% | 0.230% | 0.03% |
| 17 | Aberdeen Group plc | 1.7M | $24.7M | +154.5% | 0.212% | 0.03% |
| 18 | MORGAN STANLEY | 1.5M | $21.1M | -12.2% | 0.182% | 0.00% |
| 19 | NORGES BANK | 1.4M | $20.1M | β | 0.173% | 0.00% |
| 20 | Logos Global Management LP | 1.4M | $19.7M | β | 0.169% | 0.85% |
| 21 | Octagon Capital Advisors LP | 1.3M | $18.2M | β | 0.157% | 1.64% |
| 22 | D. E. Shaw & Co., Inc. | 1.2M | $18.1M | -44.5% | 0.156% | 0.01% |
| 23 | Kynam Capital Management, LP | 1.2M | $17.5M | β | 0.150% | 0.97% |
| 24 | Pictet Asset Management Holding SA | 1.1M | $16.4M | -14.3% | 0.142% | 0.02% |
| 25 | DIADEMA PARTNERS LP | 1.1M | $16.3M | β | 0.140% | 2.06% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in SMMT β a direct measure of their conviction.
Filings activity in SMMT during Q2 2026, grouped by how each filer changed its position.
Institutions that opened a new SMMT position in Q2 2026
Institutions that fully closed their SMMT position in Q2 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 244 | +9.4% | 17.84% | +2.13 pp | $2.01B | 7.0% |
| Q1 2026 | 223 | +5.7% | 15.71% | 0.19 pp | $2.16B | +8.1% |
| Q4 2025 | 211 | 10% | 15.90% | +0.98 pp | $2.00B | 9.1% |
| Q3 2025 | 235 | +0.9% | 14.92% | +1.19 pp | $2.20B | +6.2% |
| Q2 2025 | 233 | +15% | 13.73% | +0.99 pp | $2.07B | +22% |
| Q1 2025 | 203 | +1.5% | 12.74% | +0.51 pp | $1.70B | +14% |
| Q4 2024 | 200 | +27% | 12.23% | +0.61 pp | $1.49B | 15% |
| Q3 2024 | 158 | β | 11.62% | β | $1.75B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Latest Form 4 transactions by company officers and directors. Insider buys are widely viewed as a key fundamental indicator because executives are risking personal capital.
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| Jun 12, 2026 | Zanganeh Mahkam | Buy | 3.8M | $13.12 | $50.0M |
| Jun 4, 2026 | Soni Manmeet Singh | Buy | 25K | $14.46 | $362K |
| Jun 4, 2026 | Zanganeh Mahkam | Buy | 100K | $14.60 | $1.5M |
Quick answers to the most common questions about buying SMMT stock.
Based on Q2 2026 13F filings, institutional ownership of Summit Therapeutics Inc. stands at 17.8%, held across 244 reporting institutions.
BAKER BROS. ADVISORS LP is the largest reported institutional holder of SMMT, with approximately 32,786,348 shares worth $0.48B as of Q2 2026.
Yes β 4 widely-followed marquee investors appear among the top 25 institutional holders of SMMT, including Point72 Asset Management, L.P., CITADEL ADVISORS LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for SMMT is 75 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
52 institutions opened new positions in SMMT during Q2 2026, while 32 fully exited. 58 added to existing positions and 125 trimmed.
SMMT institutional ownership rose by 2.13 percentage points quarter-over-quarter, with a net change of +21 holders.
The top 10 institutions account for 64.9% of all reported 13F value in SMMT, and the top 25 account for 83.1%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Summit Therapeutics Inc. (SMMT) Institutional Ownership