Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in STTK held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 8.1M | $56.4M | +74.9% | 8.987% | 0.08% |
| 2 | Redmile Group, LLC | 6.9M | $47.8M | +24.4% | 7.626% | 3.21% |
| 3 | ORBIMED ADVISORS LLC | 6.3M | $43.8M | 0.0% | 6.978% | 0.81% |
| 4 | Prosight Management, LP | 6.0M | $41.3M | +19.1% | 6.593% | 7.12% |
| 5 | BlackRock, Inc. | 3.9M | $27.3M | +670.5% | 4.355% | 0.00% |
| 6 | Frazier Life Sciences Management, L.P. | 3.8M | $26.0M | — | 4.149% | 0.57% |
| 7 | NEXTBio Capital Management LP | 3.7M | $25.9M | +18.3% | 4.124% | 11.90% |
| 8 | Deep Track Capital, LP | 3.7M | $25.7M | — | 4.102% | 0.37% |
| 9 | VANGUARD CAPITAL MANAGEMENT LLC | 3.2M | $22.3M | +40.9% | 3.550% | 0.00% |
| 10 | PINNACLE ASSOCIATES LTD | 1.9M | $13.0M | +36.8% | 2.071% | 0.14% |
| 11 | WELLINGTON MANAGEMENT GROUP LLP | 1.8M | $12.3M | — | 1.956% | 0.00% |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 1.6M | $11.0M | +145.4% | 1.754% | 0.00% |
| 13 | CLARK ESTATES INC/NY | 1.4M | $9.9M | -3.1% | 1.582% | 2.29% |
| 14 | Aberdeen Group plc | 1.4M | $9.8M | +21.3% | 1.556% | 0.01% |
| 15 | Point72 Asset Management, L.P. | 1.2M | $8.1M | +13.6% | 1.295% | 0.01% |
| 16 | 683 Capital Management, LLC | 1.2M | $8.0M | +44.6% | 1.280% | 0.39% |
| 17 | STATE STREET CORP | 1.0M | $7.1M | +289.1% | 1.136% | 0.00% |
| 18 | Boxer Capital Management, LLC | 1.0M | $6.9M | — | 1.107% | 0.52% |
| 19 | VANGUARD PORTFOLIO MANAGEMENT LLC | 947K | $6.6M | — | 1.048% | 0.00% |
| 20 | RENAISSANCE TECHNOLOGIES LLC | 744K | $5.2M | +23.0% | 0.823% | 0.01% |
| 21 | GOLDMAN SACHS GROUP INC | 593K | $4.1M | +209.9% | 0.656% | 0.00% |
| 22 | TD ASSET MANAGEMENT INC | 559K | $3.9M | +46.1% | 0.618% | 0.00% |
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 533K | $3.7M | -25.5% | 0.590% | 0.00% |
| 24 | NORTHERN TRUST CORP | 520K | $3.6M | +312.8% | 0.576% | 0.00% |
| 25 | VANGUARD FIDUCIARY TRUST CO | 463K | $3.2M | +42.8% | 0.513% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in STTK — a direct measure of their conviction.
Filings activity in STTK during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 103 | +23% | 93.57% | +10.89 pp | $473M | +67% |
| Q1 2026 | 84 | +29% | 82.68% | +10.15 pp | $283M | +101% |
| Q4 2025 | 65 | +16% | 72.53% | +8.35 pp | $141M | +64% |
| Q3 2025 | 56 | 9.7% | 64.18% | +32.44 pp | $86M | +283% |
| Q2 2025 | 62 | 18% | 31.74% | 2.77 pp | $22M | 23% |
| Q1 2025 | 76 | +0.0% | 34.51% | 0.54 pp | $29M | 27% |
| Q4 2024 | 76 | +0.0% | 35.05% | 4.25 pp | $40M | 67% |
| Q3 2024 | 76 | — | 39.30% | — | $121M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying STTK stock.
Based on Q2 2026 13F filings, institutional ownership of Shattuck Labs, Inc. stands at 93.6%, held across 103 reporting institutions.
ADAGE CAPITAL PARTNERS GP, L.L.C. is the largest reported institutional holder of STTK, with approximately 8,122,179 shares worth $0.06B as of Q2 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of STTK, including Point72 Asset Management, L.P., RENAISSANCE TECHNOLOGIES LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for STTK is 77 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
38 institutions opened new positions in STTK during Q2 2026, while 17 fully exited. 48 added to existing positions and 16 trimmed.
STTK institutional ownership rose by 10.89 percentage points quarter-over-quarter, with a net change of +19 holders.
The top 10 institutions account for 69.7% of all reported 13F value in STTK, and the top 25 account for 91.6%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.