Last 47 quarters of trend data · Healthcare · Drug Manufacturers - Specialty & Generic
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -3.18 | — | — | — | — | — | — | — | — | — | — | — | — | — | 27.97 | — | — | 0.13 | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 2001.84 | — | — | — | 9256.54 | — | 120.40 | — | — | — | — | 12.09 | 20.77 | 11.98 | — | 16.74 | — | 15.50 | — | 8938.16 | 16.33 |
| — | — | — | — | — | — | — | — | — | — | — | -27.8% | — | -22.7% | — | -99.8% | — | -83.3% | — | +22956.2% | -28.4% | |
| P/B Ratio | 2.69 | 5.40 | 1.71 | 2.84 | 1.93 | 2.40 | 2.32 | 1.72 | 2.33 | 1.83 | 1.56 | 0.96 | 0.53 | 1.16 | 0.50 | 0.77 | 1.13 | 1.07 | — | — | — |
| — | +125.2% | -26.2% | +65.1% | -17.1% | +30.9% | +49.0% | +78.3% | +338.7% | +57.4% | +208.8% | +24.6% | -52.8% | +9.2% | — | — | — | — | — | — | — | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 0.12 | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 100.0% | — | — | — | 100.0% | — | -4229.6% | — | — | — | — | -529.5% | -906.8% | -513.4% | — | -43.7% | — | -53.7% | — | -61600.0% | 63.5% |
| — | — | — | — | — | — | — | — | — | — | — | -1113.1% | — | -856.4% | — | +99.9% | — | +60.2% | — | -32418.5% | +279.7% | |
| Operating Margin | -48157.1% | — | — | — | -342200.0% | — | -10800.0% | — | — | — | — | -1524.2% | -2828.2% | -1568.8% | — | -2931.0% | — | -1521.4% | — | -408750.0% | -463.6% |
| — | — | — | — | — | — | — | — | — | — | — | +48.0% | — | -3.1% | — | +99.3% | — | +32.7% | — | -32532.8% | +29.8% | |
| Net Margin | -51035.7% | — | — | — | -443600.0% | — | -9603.7% | — | — | — | — | -1607.5% | -1159.8% | -1727.7% | — | -2969.8% | — | 12397.0% | — | -395850.0% | -449.8% |
| — | — | — | — | — | — | — | — | — | — | — | +45.9% | — | -113.9% | — | +99.2% | — | +657.5% | — | -32658.2% | +31.1% |
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -114.2% | -26.2% | -14.4% | -20.8% | -34.4% | -57.1% | -38.1% | -21.2% | -30.0% | -26.3% | -26.0% | -27.9% | -9.4% | -35.4% | -45.2% | -30.3% | -22.2% | 213.2% | — | — | — |
| — | +54.1% | +62.3% | +1.7% | -14.7% | -116.7% | -46.8% | +23.9% | -217.3% | +25.7% | +42.5% | +8.1% | +57.5% | -116.6% | — | — | — | — | — | — | — | |
| ROA | -59.6% | -15.1% | -8.5% | -12.5% | -18.8% | -22.1% | -15.6% | -9.5% | -14.6% | -14.3% | -16.1% | -20.7% | -6.6% | -19.9% | -22.1% | -15.6% | -12.9% | 110.3% | -11.6% | -10.5% | -11.0% |
| — | +31.6% | +45.3% | -30.9% | -28.4% | -55.2% | +3.0% | +54.0% | -120.8% | +28.1% | +27.2% | -32.4% | +48.8% | -118.0% | -90.9% | -48.2% | -17.2% | +1034.7% | +0.7% | +21.7% | +17.5% | |
| ROIC | -86.8% | -20.8% | -18.3% | -13.0% | -18.0% | -42.4% | -35.3% | -41.9% | -51.7% | -39.2% | -33.6% | -48.3% | -62.6% | -81.9% | -38.4% | -25.3% | -11.4% | -20.1% | — | — | -114.5% |
| — | +50.9% | +48.0% | +69.0% | +65.2% | -8.2% | -4.9% | +13.2% | +17.5% | +52.2% | +12.4% | -91.1% | -450.5% | -307.7% | — | — | +90.1% | -25.1% | — | — | — |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.38 | — | — | 0.38 | 0.34 | 0.98 | 1.17 | 0.82 | 0.68 | 0.51 | 0.39 | — | — | — | 0.24 | 0.46 | 0.45 | 0.43 | — | — | — |
| — | — | — | -53.2% | -49.9% | +91.3% | +201.6% | — | — | — | +63.4% | — | — | — | — | — | — | — | — | — | — | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 5.49 | 4.29 | 5.30 | 5.49 | 6.83 | 2.93 | 3.11 | 3.56 | 4.42 | 4.90 | 5.97 | 2.56 | 4.04 | 2.09 | 1.83 | 1.78 | 1.57 | 1.81 | 2.51 | 2.73 | 3.03 |
| — | +46.8% | +70.7% | +54.2% | +54.6% | -40.3% | -48.0% | +38.9% | +9.4% | +133.9% | +225.4% | +43.6% | +157.3% | +15.8% | -27.0% | -34.6% | -48.3% | -53.4% | -45.2% | +2.7% | +5.0% | |
| Quick Ratio | 5.49 | 4.29 | 5.30 | 5.49 | 6.83 | 2.93 | 3.11 | 3.56 | 4.42 | 4.90 | 5.97 | 2.56 | 4.03 | 2.09 | 1.83 | 1.70 | 1.51 | 1.76 | 2.45 | 2.67 | 2.94 |
| — | +46.8% | +70.7% | +54.2% | +54.6% | -40.3% | -48.0% | +38.9% | +9.5% | +133.9% | +225.4% | +50.8% | +166.8% | +19.1% | -25.2% | -36.3% | -48.6% | -53.7% | -45.5% | +4.1% | +6.3% | |
| Interest Coverage | — | — | — | — | — | — | — | — | — | -16.97 | -20.85 | — | — | -264.60 | -44.77 | -38.60 | -17.89 | — | — | -15.95 | -14.57 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 47 years · Updated daily
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Quick answers to the most common questions about buying TLPH stock.
Talphera, Inc.'s current P/E is -3.2x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Talphera, Inc.'s current operating margin is -48157.1%. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Talphera, Inc.'s business trajectory between earnings reports.