Talphera, Inc. (TLPH) P/E Ratio History
Historical price-to-earnings valuation from 2022 to 2023
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TLPH Valuation Context
How does the current P/E compare to historical and market benchmarks?
P/E Ratio Analysis
As of May 10, 2026, Talphera, Inc. (TLPH) trades at a price-to-earnings ratio of -2.7x, with a stock price of $0.90 and trailing twelve-month earnings per share of $-0.34.
The current P/E is 646% below its 5-year average of 0.5x. Over the past five years, TLPH's P/E has ranged from a low of 0.1x to a high of 0.8x, placing the current valuation at the 0th percentile of its historical range.
Compared to the Healthcare sector median P/E of 21.9x, TLPH trades at a 112% discount to its sector peers. The sector includes 241 companies with P/E ratios ranging from 0.0x to 176.0x.
Relative to the broader market, TLPH trades at a notable discount to the S&P 500 median P/E of 24.9x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our TLPH DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
TLPH P/E vs Peers
P/E ratio compared to closely matched public peers
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $8B | 25.0 | 1.09 | -25% | |
| $911M | 144.7 | - | +107% | |
| $2B | 6.9Lowest | 0.67Best | +817%Best | |
| $90B | 19.2 | - | +49% | |
| $43B | 28.5 | - | +87% |
Peers sorted by market capitalization. P/E below peers may indicate undervaluation or lower growth expectations. Consider PEG ratio for growth-adjusted comparison.
TLPH Historical P/E Data (2022–2023)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Date | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2023 Q1 | Fri Mar 31 2023 00:00:00 GM | $0.66 | $6.94 | 0.1x | -80% |
| FY2022 Q4 | Sat Dec 31 2022 00:00:00 GM | $2.26 | $6.50 | 0.3x | -29% |
| FY2022 Q3 | Fri Sep 30 2022 00:00:00 GM | $4.20 | $6.26 | 0.7x | +38% |
| FY2022 Q2 | $4.80 | $5.77 | 0.8x | +71% |
Average P/E for displayed period: 0.5x
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Start ComparisonTLPH — Frequently Asked Questions
Quick answers to the most common questions about buying TLPH stock.
Is TLPH stock overvalued or undervalued?
TLPH trades at -2.7x P/E, below its 5-year average of 0.5x. At the N/A percentile of historical range, the stock is priced at a discount to its own history.
How does TLPH's valuation compare to peers?
Talphera, Inc. P/E of -2.7x compares to sector median of 21.9x. The discount suggests lower growth expectations or higher risk.
What is TLPH's PEG ratio?
TLPH PEG ratio is N/A. Above 2.0 indicates premium valuation relative to growth rate. Historical P/E data spans 2022-2023.