Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in TLPH held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | AIGH Capital Management LLC | 4.7M | $3.5M | 0.0% | 10.991% | 0.71% |
| 2 | Rock Springs Capital Management LP | 3.6M | $2.7M | 0.0% | 8.463% | 0.16% |
| 3 | Nantahala Capital Management, LLC | 3.5M | $2.6M | 0.0% | 8.235% | 0.13% |
| 4 | Rosalind Advisors, Inc. | 3.4M | $2.5M | -6.3% | 7.908% | 1.03% |
| 5 | Bleichroeder LP | 1.3M | $977K | +48.4% | 3.084% | 0.17% |
| 6 | CANTOR FITZGERALD, L. P. | 887K | $663K | +53.7% | 2.093% | 0.02% |
| 7 | Empery Asset Management, LP | 590K | $441K | -55.7% | 1.392% | 0.53% |
| 8 | Caption Management, LLC | 562K | $420K | β | 1.325% | 0.00% |
| 9 | Almitas Capital LLC | 467K | $349K | β | 1.102% | 0.08% |
| 10 | VANGUARD CAPITAL MANAGEMENT LLC | 442K | $330K | β | 1.041% | 0.00% |
| 11 | Dauntless Investment Group, LLC | 435K | $325K | -24.9% | 1.026% | 0.87% |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 420K | $314K | +22.4% | 0.990% | 0.00% |
| 13 | Shay Capital LLC | 250K | $187K | β | 0.590% | 0.02% |
| 14 | RENAISSANCE TECHNOLOGIES LLC | 238K | $178K | -7.6% | 0.561% | 0.00% |
| 15 | VANGUARD FIDUCIARY TRUST CO | 192K | $144K | β | 0.454% | 0.00% |
| 16 | DIADEMA PARTNERS LP | 154K | $115K | +12.2% | 0.362% | 0.04% |
| 17 | Mariner, LLC | 100K | $75K | +72.4% | 0.236% | 0.00% |
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 97K | $73K | -65.4% | 0.229% | 0.00% |
| 19 | BlackRock, Inc. | 92K | $68K | 0.0% | 0.216% | 0.00% |
| 20 | NORTHERN TRUST CORP | 88K | $66K | +67.9% | 0.208% | 0.00% |
| 21 | Values First Advisors, Inc. | 82K | $61K | +0.4% | 0.192% | 0.03% |
| 22 | Persistent Asset Partners Ltd | 39K | $29K | +6.4% | 0.092% | 0.01% |
| 23 | Vanguard Global Advisers, LLC | 30K | $22K | β | 0.070% | 0.00% |
| 24 | XTX Topco Ltd | 26K | $19K | β | 0.061% | 0.00% |
| 25 | STATE STREET CORP | 22K | $17K | 0.0% | 0.052% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in TLPH β a direct measure of their conviction.
Filings activity in TLPH during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new TLPH position in Q1 2026
Institutions that fully closed their TLPH position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 44 | +19% | 43.75% | 21.44 pp | $16M | 33% |
| Q4 2025 | 37 | +8.8% | 65.19% | +22.39 pp | $24M | +52% |
| Q3 2025 | 34 | +6.3% | 42.80% | +36.23 pp | $16M | +551% |
| Q2 2025 | 32 | 5.9% | 6.57% | 0.84 pp | $2M | 11% |
| Q1 2025 | 34 | +3.0% | 7.41% | +1.75 pp | $3M | +31% |
| Q4 2024 | 33 | +14% | 5.66% | 3.53 pp | $2M | 38% |
| Q3 2024 | 29 | +0.0% | 9.19% | 0.49 pp | $3M | 5.1% |
| Q2 2024 | 29 | β | 9.68% | β | $4M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying TLPH stock.
Based on Q1 2026 13F filings, institutional ownership of Talphera, Inc. stands at 43.8%, held across 44 reporting institutions.
AIGH Capital Management LLC is the largest reported institutional holder of TLPH, with approximately 4,661,502 shares worth $0.00B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of TLPH, including RENAISSANCE TECHNOLOGIES LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for TLPH is 51 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
13 institutions opened new positions in TLPH during Q1 2026, while 6 fully exited. 5 added to existing positions and 26 trimmed.
TLPH institutional ownership fell by 21.44 percentage points quarter-over-quarter, with a net change of +7 holders.
The top 10 institutions account for 89.2% of all reported 13F value in TLPH, and the top 25 account for 99.6%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Talphera, Inc. (TLPH) Institutional Ownership