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TLSATiziana Life Sciences Ltd
$0.89$66M
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TLSA logo

Tiziana Life Sciences Ltd

TLSA
NASDAQ · Biotechnology
$0.89
At close - Sep 22, 4:00 PM EDT - USD
Market Cap$57M
P/E-2.8x
52W High$2.35
Volume623.15K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2025Q4

Clinical Development Costs Threaten Capital Base Sustainability

Tiziana Life Sciences remains a pre-revenue biotechnology entity entirely dependent on external financing to sustain its intranasal Foralumab clinical pipeline. The company faces significant solvency risks as its equity base has eroded to a nominal $52.0K, nec...

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

TLSA price & volume

Price trend, volume and key moving averages

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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

0/12 Beats

EPS beat 0 of last 12 quarters

02

Valuation risk

-117% Peers

P/E is 117% below peer median

03

Market leadership

RS 16 · Lag

Laggard (Underperforming 84% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Dec 18

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
TLSA-44.38%
S&P 500 (^GSPC)+13.20%
1-Year Return
TLSA-51.10%
S&P 500 (^GSPC)+15.98%
3-Year Return
TLSA+35.04%
S&P 500 (^GSPC)+81.86%
5-Year Return
TLSA-44.38%
S&P 500 (^GSPC)+73.82%

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$18M-55.4% YoY
Free cash flow
-$13M-942.3% YoY
Operating margin
-
ROIC (TTM)-
Avg ROIC 5Y-
ROE (TTM)-924.3%
Piotroski Score1 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate0/12 (0%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Sep 18, 2026
-$0.08+0.0%
vs -$0.08
—
vs —
Q2 2026
May 1, 2026
-$0.22-143.0%
vs -$0.09
—
vs —
Q4 2025
Oct 3, 2025
-$0.10-35.4%
vs -$0.07
—
vs —
Q3 2025
Jul 8, 2025
-$0.06
vs —
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Proactive Investors·3d ago
Tiziana Life Sciences completes patient visits in Phase 2a MS drug trial

Tiziana Life Sciences Ltd (NASDAQ:TLSA) said Monday the last patient has completed their final visit in the company's Phase 2a clinical trial evaluating intranasal foralumab in patients with non-active secondary progressive multiple sclerosis (na-SPMS). The randomized, double-blind, placebo-controlled INFORM-MS trial enrolled 48 patients across three cohorts at multiple leading U.S.

Proactive Investors·Sep 17, 2026
Tiziana Life Sciences partners with Saudi institutions on MS combination therapy trial

Tiziana Life Sciences Ltd (NASDAQ:TLSA) has signed a Memorandum of Understanding with the King Abdullah International Medical Research Center (KAIMRC) and the Foundation for Neurologic Diseases to study its intranasal foralumab in combination with anti-CD20 therapy for multiple sclerosis patients. The planned trial will target relapsing-remitting multiple sclerosis (RRMS) patients who respond poorly to anti-CD20 therapy alone, a shortfall that may stem from untreated neuroinflammation.

Proactive Investors·Sep 3, 2026
Tiziana Life Sciences gets Buy rating from BTIG on Treg-based approach to neurodegeneration

Tiziana Life Sciences Ltd (NASDAQ:TLSA) was awarded a Buy rating with a $7 price target by BTIG, which pointed to the biotech's approach to modulating central nervous system inflammation as a potential leading treatment for neurodegenerative disease. The clinical-stage company is developing foralumab, an anti-CD3 antibody delivered via nasal spray, to stimulate regulatory T-cell (Treg) production and reduce the inflammatory processes that drive neurodegeneration.

Proactive Investors - Finance·Sep 3, 2026
Dow climbs as stocks rebound on earnings, falling Treasury yields

3:40pm: Small cap wrap Tiziana Life Sciences Ltd (NASDAQ:TLSA) received a Buy rating and $7 price target from BTIG, which highlighted its nasal anti-CD3...

Filtered for Tiziana Life Sciences LtdMore Headlines
04

Compare before deciding

Benchmark TLSA against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Tiziana Life Sciences Ltd (TLSA)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
TLSA logoTLSATiziana Life Sciences LtdCurrent
$0.89$56.62M-2.78——-924.32%—
IMVT logoIMVTImmunovant, Inc.
$37.29$7.7B-13.46—-7585.86%-69.59%—
ARCT logoARCTArcturus Therapeutics Holdings Inc.
$14.38$408.72M-5.99-51.43%-391.9%-46.54%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$300.65$8.38B-22.30-100%—-34.15%—
KYMR logoKYMRKymera Therapeutics, Inc.
$122.06$10.04B-33.08-16.72%-285.41%-21.5%—
RCUS logoRCUSArcus Biosciences, Inc.
$26.87$3.38B-8.17-4.26%-386.32%-87.98%—

Compare TLSA vs Peers

Tiziana Life Sciences Ltd (TLSA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for TLSA.

Scale Benchmark

vs MEDP

Larger-name benchmark to compare TLSA against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, ARCT, PRAX, KYMR

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TLSA Frequently Asked Questions

Tiziana Life Sciences Ltd (TLSA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is TLSA profitable?

Tiziana Life Sciences Ltd (TLSA) reported a net loss of $34.9M for fiscal year 2025.

Dividend & Returns
What is TLSA's return on equity?

Tiziana Life Sciences Ltd (TLSA) has a return on equity (ROE) of -924.3%. Negative ROE indicates the company is unprofitable.

What is Tiziana Life Sciences Ltd's free cash flow?

Tiziana Life Sciences Ltd (TLSA) had negative free cash flow of $14.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in TLSA back in 1998?

Total return calculator · dividends reinvested · 28+ years of data

See returns →