Operating cash flow turned positive at $1.1M in 2026Q3, but free cash flow remained negative at -$8.5M, with capex rising to 8.2% of revenue and stock-based compensation of $18.2M masking true cash burn.
Twist Bioscience Corporation (TWST) cash flow statement — 10-year operating, investing & financing cash flows
| Metric | TTM | Sep'25 | Sep'24 | Sep'23 | Sep'22 | Sep'21 | Sep'20 | Sep'19 | Sep'18 | Sep'17 | Sep'16 |
|---|
| Cash from Operations | -53.07M | -47.63M | -64.09M | -142.47M | -124.39M | -112.24M | -142.25M | -87.94M | -66.16M | -51.3M | -38.59M |
| Operating CF Margin % | - | -12.65% | -20.48% | -58.13% | -61.1% | -84.82% | -157.89% | -161.69% | -260.21% | -476.47% | -1700.84% |
| Operating CF Growth % | 151.51% | 25.69% | 55.01% | -14.54% | -10.82% | 21.1% | -61.77% | -32.91% | -28.97% | -32.93% | - |
| Net Income | -136.72M | -77.67M | -208.73M | -204.62M | -217.86M | -152.1M | -139.93M | -107.67M | -71.24M | -59.31M | -44.09M |
| Depreciation & Amortization | 25.39M | 24.85M | 31.43M | 29.31M | 16.51M | 9.75M | 6.68M | 6.11M | 5.73M | 5.02M | 4.23M |
| Stock-Based Compensation | 66.47M | 64.46M | 50.92M | 30.28M | 79.66M | 37M | 17.1M | 11.17M | 2.96M | 1.89M | 857K |
| Deferred Taxes | 0 | 0 | 0 | -410K | 0 | 0 | -214K | -1.06M | 42K | 768K | -68K |
| Other Non-Cash Items | 7.27M | -46.66M | 46.86M | 3.98M | 2.66M | 2.49M | -707K | 515K | 562K | 458K | 238K |
| Working Capital Changes | -15.49M | -12.61M | 15.41M | -1.01M | -5.36M | -9.38M | -25.18M | 3M | -4.22M | -129K | 240K |
| Change in Receivables | -15.71M | -22.38M | 8.44M | -4.32M | -9.62M | -2.2M | -14.27M | -6.68M | -3.07M | -1.62M | -702K |
| Change in Inventory | -9.22M | -4.23M | 7.99M | 7.24M | -7.54M | -19.49M | -4.96M | -1.3M | -4.2M | -599K | -1.23M |
| Change in Payables | 4.3M | 9.33M | -11.8M | -2.51M | 7.38M | 8.54M | -5.51M | 3.28M | 3.76M | 560K | 466K |
| Cash from Investing | -45.24M | -24.76M | -3.07M | 50.61M | -232.93M | 156.16M | -114.65M | -104.81M | 26.87M | -9.87M | -33.34M |
| Capital Expenditures | -40.05M | -28M | -5.08M | -27.78M | -101.86M | -27.06M | -9.87M | -14.76M | -3.69M | -6.59M | -6.23M |
| CapEx % of Revenue | 9.28% | 7.44% | 1.62% | 11.33% | 50.04% | 20.45% | 10.95% | 27.13% | 14.5% | 61.24% | 274.53% |
| Acquisitions | 0 | 2.5M | 0 | 5.86M | -8.16M | -483K | 104.78M | 21K | 17K | 266K | 254K |
| Investments | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -5.1M | 0 | 0 | -5.86M | -5.75M | 0 | -104.78M | -90.05M | -434K | 120K | 174K |
| Cash from Financing | 13.8M | 28.54M | 6.89M | 911K | 270.53M | 329.18M | 303.73M | 158.58M | 88.82M | 63.8M | 69.65M |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | -1.56M | -3.33M | -3.33M | -2.5M | 0 | -2M | 7.23M |
| Equity Issued (Net) | 8.22M | 13.54M | -3.98M | -4.41M | 262.07M | 313.01M | 293.14M | 156.21M | 90.85M | 65.6M | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -18K | -16K | -3.98M | -4.41M | -7.75M | -10.85M | -2.42M | 0 | 0 | 0 | 0 |
| Other Financing | 5.58M | 15M | 10.87M | 5.32M | 10.02M | 19.5M | 13.92M | 4.87M | -2.03M | 205K | 62.42M |
| Net Change in Cash | -84.34M | -43.27M | -60.15M | -90.98M | -87.1M | 373.11M | 46.85M | -34.14M | 49.53M | 2.63M | -2.29M |
| Free Cash Flow | -93.12M | -75.63M | -69.17M | -170.25M | -226.24M | -139.31M | -152.12M | -102.69M | -69.85M | -57.9M | -44.82M |
| FCF Margin % | -21.57% | -20.08% | -22.1% | -69.46% | -111.14% | -105.27% | -168.84% | -188.83% | -274.72% | -537.71% | -1975.36% |
| FCF Growth % | -35.52% | -9.34% | 59.37% | 24.75% | -62.41% | 8.43% | -48.13% | -47.02% | -20.65% | -29.17% | - |
| FCF per Share | -1.49 | -1.26 | -1.19 | -2.99 | -4.20 | -2.89 | -3.88 | -3.74 | -2.63 | -3.08 | -2.39 |
| FCF Conversion (FCF/Net Income) | 0.68x | 0.61x | 0.31x | 0.70x | 0.57x | 0.74x | 1.02x | 0.82x | 0.93x | 0.86x | 0.88x |
| Interest Paid | 0 | 0 | 0 | 0 | 9K | 167K | 438K | 779K | 751K | 702K | 391K |
| Taxes Paid | 161K | 683K | 344K | 420K | 246K | 101K | 172K | 291K | 179K | 6K | 14K |
Quick answers to the most common questions about buying TWST stock.
Twist Bioscience Corporation (TWST) generated $-47.6M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Twist Bioscience Corporation (TWST) reported negative free cash flow of $75.6M in 2025, indicating capital requirements exceeded cash from operations.
Twist Bioscience Corporation (TWST) spent $28.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
In 2025, Twist Bioscience Corporation (TWST) spent $0.0M on share repurchases. This shows the company's commitment to returning capital to its equity investors.
Key Metrics
Top Statement Risk
Persistent operating losses and dilution
Metrics are mathematically derived from official filings.
Cash Conversion Remains Elusive
Despite a $35.1M net loss in 2026Q3, operating cash flow turned positive at $1.1M, a rare occurrence, as per recent SEC filings, suggesting non-cash charges are masking underlying cash burn.
The OCF/NI ratio of -0.03 in 2026Q3 indicates that operating cash flow is not yet a reliable indicator of earnings quality, as the company continues to report substantial net losses. The positive OCF appears driven by a $3.3M working capital benefit and $18.2M in stock-based compensation, which are non-cash in nature. Investors should monitor whether this positive OCF is sustainable or a one-off, given the historical pattern of negative OCF in most quarters.
FCF Burn Persists Despite Revenue Growth
Free cash flow remained negative at -$8.5M in 2026Q3, though it improved from -$34.8M in 2026Q1, as reported in financial statements, reflecting a narrowing burn rate but still far from breakeven.
The FCF margin improved to -7.2% in 2026Q3 from -33.5% in 2026Q1, suggesting that revenue growth is beginning to outpace cash outflows, but the company is still consuming cash at a significant rate. The positive OCF in 2026Q3 is a notable inflection, yet the cumulative FCF over the last ten quarters remains deeply negative, indicating that the company has not yet reached a self-sustaining cash flow position. This trajectory suggests that external funding may be needed if the burn rate does not continue to decline.
Capital Intensity Rises with Expansion
Capital expenditures jumped to $9.8M in 2026Q3, representing 8.2% of revenue, up from 0.8% in 2024Q2, according to reported figures, signaling a strategic shift toward scaling manufacturing capacity.
The sharp increase in capex, from under $1M per quarter in 2024 to nearly $10M in 2026Q3, suggests that Twist is investing heavily in its 'Factory of the Future' to support future growth. This elevated capital intensity may pressure near-term FCF, but it appears aligned with management's strategy to achieve scale and improve gross margins over time. Investors should monitor whether this capex translates into higher utilization and margin expansion, as the current depreciation expense of ~$6-7M per quarter is already a significant fixed cost.
Working Capital Swings Add Volatility
Working capital changes swung from -$13.4M in 2026Q1 to +$3.3M in 2026Q3, as per financial statements, indicating that cash flow is increasingly sensitive to inventory and receivables management.
The positive working capital contribution in 2026Q3 helped drive the positive OCF, but the prior quarter's negative swing of -$13.4M highlights the lumpiness in cash flow from operations. This volatility may reflect customer ordering patterns, particularly in the NGS segment, where pilot programs can lead to inventory stocking effects. Investors should watch for sustained improvements in working capital efficiency, as the company scales, to reduce cash flow unpredictability.
Minimal Capital Returns, Focus on Growth
Twist paid no dividends and repurchased only $6,000 in stock in 2026Q3, as reported in SEC filings, indicating that all available cash is being reinvested into the business.
The absence of shareholder returns is consistent with a pre-profitability growth company that is prioritizing investment in manufacturing capacity and R&D. The negligible buyback activity suggests that management is not attempting to support the stock price through capital returns, which may be prudent given the cash burn. Investors should monitor the cash runway, as the company's net margin of -20.63% and negative FCF imply a potential need for future equity raises if losses persist.
Non-Cash Charges Mask True Burn
Stock-based compensation of $18.2M in 2026Q3, as per financial statements, exceeds the net loss, suggesting that the actual cash burn is higher than reported operating losses indicate.
The significant SBC expense, which has averaged around $15M per quarter, is a non-cash charge that inflates reported losses but also dilutes shareholders. When adjusting for SBC, the company's cash operating losses are narrower, but the positive OCF in 2026Q3 appears to be partly due to working capital timing rather than operational profitability. Investors should adjust for SBC to assess the true cash generation capability, as the company's path to GAAP profitability may be longer than headline numbers suggest.