| Woodline Partners LP |
| 1.1M |
| $47.4M |
| +74.1% |
| 8.886% |
| 0.15% |
| 5 | Newtyn Management, LLC | 709K | $30.1M | β | 5.655% | 3.76% |
| 6 | BlackRock, Inc. | 692K | $29.4M | +7.0% | 5.518% | 0.00% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 505K | $21.5M | -8.1% | 4.028% | 0.00% |
| 8 | Opaleye Management Inc. | 338K | $14.4M | +12.8% | 2.698% | 1.30% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 245K | $10.4M | +6.8% | 1.956% | 0.00% |
| 10 | WATER ISLAND CAPITAL LLC | 242K | $10.3M | β | 1.930% | 0.96% |
| 11 | ALPINE ASSOCIATES MANAGEMENT INC. | 239K | $10.2M | β | 1.908% | 0.64% |
| 12 | MILLENNIUM MANAGEMENT LLC | 227K | $9.6M | +10.5% | 1.806% | 0.00% |
| 13 | STATE STREET CORP | 198K | $8.4M | +2.4% | 1.577% | 0.00% |
| 14 | DIMENSIONAL FUND ADVISORS LP | 177K | $7.5M | +32.8% | 1.412% | 0.00% |
| 15 | HSBC HOLDINGS PLC | 150K | $6.3M | β | 1.192% | 0.00% |
| 16 | TORNO CAPITAL, LLC | 140K | $5.9M | β | 1.114% | 0.17% |
| 17 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 134K | $5.7M | +458.7% | 1.069% | 0.00% |
| 18 | NORTHERN TRUST CORP | 96K | $4.1M | +2.9% | 0.767% | 0.00% |
| 19 | VANGUARD PORTFOLIO MANAGEMENT LLC | 90K | $3.8M | +5.3% | 0.720% | 0.00% |
| 20 | TUDOR INVESTMENT CORP ET AL | 84K | $3.6M | β | 0.673% | 0.00% |
| 21 | Bank of New York Mellon Corp | 75K | $3.2M | +0.5% | 0.601% | 0.00% |
| 22 | Verition Fund Management LLC | 71K | $3.0M | β | 0.563% | 0.01% |
| 23 | VANGUARD FIDUCIARY TRUST CO | 70K | $3.0M | +5.3% | 0.560% | 0.00% |
| 24 | Simcoe Capital LLC | 68K | $2.9M | 0.0% | 0.543% | 1.76% |
| 25 | JANE STREET GROUP, LLC | 57K | $2.4M | +128.0% | 0.458% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in XOMA β a direct measure of their conviction.
Institutions that fully closed their XOMA position in Q2 2026
| 62.32% |
| +0.33 pp |
| $154M |
| 24% |
| Q4 2024 | 65 | 1.5% | 61.99% | 0.05 pp | $201M | +1.1% |
| Q3 2024 | 66 | β | 62.04% | β | $199M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
31 institutions opened new positions in XOMA during Q2 2026, while 15 fully exited. 54 added to existing positions and 14 trimmed.
XOMA institutional ownership rose by 57.60 percentage points quarter-over-quarter, with a net change of +15 holders.
The top 10 institutions account for 85.6% of all reported 13F value in XOMA, and the top 25 account for 96.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.