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iSpecimen Inc. (ISPC) Total Return Calculator with Dividends Reinvested

iSpecimen Inc.

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The total return for iSpecimen Inc. (ISPC) stock is -88.19% over the past 12 months. So far it's down 53.76% this year. The 5-year total return is -99.91%, meaning $10,000 invested in ISPC stock 5 years ago would be worth $9 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in ISPC 1 year ago, it would be worth $1,123 today — you'd have lost $8,877.

With Dividends Reinvested$1,123-88.77%

Price Only (No DRIP)$1,123-88.77%

Period2025-05-08 → 2026-05-08

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in ISPC

1Y$1,181-$8,819 (-88.2%)-88.2% CAGR

3Y$42-$9,958 (-99.6%)-83.9% CAGR

5Y$9-$9,991 (-99.9%)-75.3% CAGR

10Y$9-$9,991 (-99.9%)-50.3% CAGR

15Y$9-$9,991 (-99.9%)-37.2% CAGR

20Y$9-$9,991 (-99.9%)-29.5% CAGR

30Y$9-$9,991 (-99.9%)-20.8% CAGR

iSpecimen Inc. did not pay dividends during this period. Total return = price return.

Loading ISPC total return...

As of 2026-05-08

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-53.76%	—	-53.76%	—	$4,624
1Y	-88.19%	-88.19%	-88.19%	—	$1,181
3Y	-99.58%	-83.92%	-99.58%	—	$42
5Y	-99.91%	-75.27%	-99.91%	—	$9
10Y	-99.91%	-50.27%	-99.91%	—	$9
15Y	-99.91%	-37.23%	-99.91%	—	$9
20Y	-99.91%	-29.48%	-99.91%	—	$9
30Y	-99.91%	-20.77%	-99.91%	—	$9

Risk & Highlights

Best Year+9.23%2021

Worst Year-90.61%2025

Max Drawdown-99.51%2025-09-12 → 2026-01-24

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-12.59%	-12.59%	—	+0.41%	-13.0pp
2025	-90.61%	-90.61%	—	+16.64%	-107.3pp
2024	-74.67%	-74.67%	—	+24.00%	-98.7pp
2023	-64.50%	-64.50%	—	+24.81%	-89.3pp
2022	-82.94%	-82.94%	—	-19.95%	-63.0pp

ISPC underperformed the S&P 500 by 118.56pp over the past year (-88.19% vs +30.37%).

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ISPC Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
ISPCiSpecimen Inc.	$734,580	-8.2%	-53.8%	-88.2%	—	-99.6%	-99.9%	-99.9%
BRLTBrilliant Earth Group, Inc.	$223M	+8.5%	-21.2%	+6.4%	+16.0pp	-58.2%	-90.3%	-90.3%
MEDPMedpace Holdings, Inc.	$12.2B	-15.7%	-24.9%	+42.9%	—	+104.6%	+159.4%	+1442.7%
BLFSBioLife Solutions, Inc.	$1.1B	+20.9%	-3.2%	+8.3%	—	+20.7%	-27.0%	+1221.1%
ICLRICON Public Limited Company	$9.5B	+16.6%	-33.7%	-10.0%	—	-34.1%	-45.4%	+91.0%
CRLCharles River Laboratories International, Inc.	$9.0B	+7.3%	-10.1%	+32.8%	—	-4.2%	-46.9%	+119.2%
LMATLeMaitre Vascular, Inc.	$2.5B	-2.2%	+34.9%	+33.3%	+1.0pp	+65.2%	+118.2%	+608.6%
QDELQuidelOrtho Corporation	$733M	-28.1%	-62.6%	-58.3%	—	-87.8%	-91.1%	-34.9%
NTRANatera, Inc.	$31.2B	+5.0%	-3.9%	+37.3%	—	+314.0%	+115.9%	+2089.4%
TMOThermo Fisher Scientific Inc.	$176.4B	-3.1%	-19.8%	+16.8%	+0.4pp	-11.7%	+2.8%	+229.1%
DHRDanaher Corporation	$124.3B	-8.0%	-23.6%	-8.3%	+0.7pp	-15.5%	-21.1%	+219.3%

Compare:ISPC vs BRLT ISPC vs MEDP ISPC vs BLFS ISPC vs BRLT vs MEDP

About ISPC Dividend Returns

iSpecimen Inc. (ISPC) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of ISPC over the past year?

iSpecimen Inc. (ISPC) delivered a return of -88.19% over the past year. Since ISPC does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in ISPC be worth today?

A $10,000 investment in iSpecimen Inc. one year ago would be worth $1,181 today, representing a loss of $8,819.

Q3Does ISPC pay dividends?

iSpecimen Inc. (ISPC) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For ISPC, the total return equals the price-only return.

Q4Did ISPC beat the S&P 500?

No, iSpecimen Inc. (ISPC) underperformed the S&P 500 by 118.56 percentage points over the past year. ISPC delivered a total return of -88.19%, compared to the S&P 500's 30.37%. This means a passive S&P 500 index fund outperformed ISPC by 118.56pp during this period.

Q5What is ISPC's worst drawdown?

iSpecimen Inc. (ISPC) experienced a maximum drawdown of -99.51% over the past year, declining from its peak on 2025-09-12 to its trough on 2026-01-24. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is ISPC's long-term total return over 10, 20, or 30 years?

Here are iSpecimen Inc. (ISPC)'s long-term returns with dividends reinvested. Over 10 years, the total return is -99.9% (-50.3% CAGR) — $10,000 would have grown to $9. Over 20 years: -99.9% total return (-29.5% CAGR) — $10,000 → $9. Over 30 years: -99.9% total return (-20.8% CAGR) — $10,000 → $9. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was ISPC's best and worst year?

iSpecimen Inc.'s best calendar year was 2021 with a total return of 9.2%. Its worst year was 2025 with a total return of -90.6%. This range shows the volatility investors should expect — the difference between the best and worst year is 99.8 percentage points.