Biotechnology
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4 / 10Stock Comparison
INO vs DVAX vs NVAX vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - Specialty & Generic
Biotechnology
Biotechnology
INO vs DVAX vs NVAX vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - Specialty & Generic | Biotechnology | Biotechnology |
| Market Cap | $642M | $1.82B | $1.50B | $5.53B |
| Revenue (TTM) | $0.00 | $331M | $596M | $0.00 |
| Net Income (TTM) | $-84.95B | $-43M | $-88M | $-464M |
| Gross Margin | — | 83.2% | 84.6% | — |
| Operating Margin | — | 3.2% | -11.2% | — |
| Forward P/E | — | 31.6x | 3.6x | — |
| Total Debt | $9.37B | $254M | $249M | $98K |
| Cash & Equiv. | $44.27B | $96M | $241M | $714M |
INO vs DVAX vs NVAX vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Inovio Pharmaceutic… (INO) | 100 | 0.8 | -99.2% |
| Dynavax Technologie… (DVAX) | 100 | 253.1 | +153.1% |
| Novavax, Inc. (NVAX) | 100 | 20.0 | -80.0% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: INO vs DVAX vs NVAX vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
INO is the clearest fit if your priority is income & stability.
- Dividend streak 0 yrs, beta 1.31
DVAX has the current edge in this matchup, primarily because of its strength in sleep-well-at-night and defensive.
- Lower volatility, beta 0.75, Low D/E 42.6%, current ratio 10.80x
- Beta 0.75, current ratio 10.80x
- Beta 0.75 vs NVAX's 2.11
- -4.6% ROA vs INO's -455.9%
NVAX is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 64.7%, EPS growth 306.5%, 3Y rev CAGR -11.1%
- 64.7% revenue growth vs INO's -100.0%
- Better valuation composite
IMVT is the clearest fit if your priority is long-term compounding.
- 173.6% 10Y total return vs DVAX's 2.9%
- 3.2% margin vs NVAX's -14.7%
- +96.1% vs INO's -22.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 64.7% revenue growth vs INO's -100.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 3.2% margin vs NVAX's -14.7% | |
| Stability / Safety | Beta 0.75 vs NVAX's 2.11 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +96.1% vs INO's -22.2% | |
| Efficiency (ROA) | -4.6% ROA vs INO's -455.9% |
INO vs DVAX vs NVAX vs IMVT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
INO vs DVAX vs NVAX vs IMVT — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
DVAX leads in 3 of 6 categories
NVAX leads 2 • IMVT leads 1 • INO leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
DVAX leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVAX and IMVT operate at a comparable scale, with $596M and $0 in trailing revenue. Profitability is closely matched — net margins range from -13.1% (DVAX) to -14.7% (NVAX). On growth, DVAX holds the edge at +17.7% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $331M | $596M | $0 |
| EBITDAEarnings before interest/tax | -$86.8B | $19M | -$47M | -$487M |
| Net IncomeAfter-tax profit | -$84.9B | -$43M | -$88M | -$464M |
| Free Cash FlowCash after capex | -$19.4B | $81M | -$96M | -$423M |
| Gross MarginGross profit ÷ Revenue | — | +83.2% | +84.6% | — |
| Operating MarginEBIT ÷ Revenue | — | +3.2% | -11.2% | — |
| Net MarginNet income ÷ Revenue | — | -13.1% | -14.7% | — |
| FCF MarginFCF ÷ Revenue | — | +24.4% | -16.1% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | -155.9% | +17.7% | -79.1% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +1036.4% | +90.9% | -102.0% | +19.7% |
Valuation Metrics
NVAX leads this category, winning 2 of 4 comparable metrics.
Valuation Metrics
At 3.6x trailing earnings, NVAX trades at a 95% valuation discount to DVAX's 77.5x P/E. On an enterprise value basis, NVAX's 2.6x EV/EBITDA is more attractive than DVAX's 503.2x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $642M | $1.8B | $1.5B | $5.5B |
| Enterprise ValueMkt cap + debt − cash | -$34.3B | $2.0B | $1.5B | $4.8B |
| Trailing P/EPrice ÷ TTM EPS | -0.76x | 77.50x | 3.63x | -9.97x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 31.59x | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | 503.23x | 2.56x | — |
| Price / SalesMarket cap ÷ Revenue | — | 6.56x | 1.34x | — |
| Price / BookPrice ÷ Book value/share | 0.03x | 3.46x | — | 5.83x |
| Price / FCFMarket cap ÷ FCF | — | 30.24x | — | — |
Profitability & Efficiency
DVAX leads this category, winning 3 of 8 comparable metrics.
Profitability & Efficiency
DVAX delivers a -8.1% return on equity — every $100 of shareholder capital generates $-8 in annual profit, vs $-14 for INO. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to DVAX's 0.43x. On the Piotroski fundamental quality scale (0–9), DVAX scores 6/9 vs INO's 0/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -14.1% | -8.1% | — | -47.1% |
| ROA (TTM)Return on assets | -4.6% | -4.6% | -7.4% | -44.1% |
| ROICReturn on invested capital | — | -0.4% | — | — |
| ROCEReturn on capital employed | -5.7% | -0.4% | +100.4% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 0 | 6 | 5 | 2 |
| Debt / EquityFinancial leverage | 0.39x | 0.43x | — | 0.00x |
| Net DebtTotal debt minus cash | -$34.9B | $159M | $8M | -$714M |
| Cash & Equiv.Liquid assets | $44.3B | $96M | $241M | $714M |
| Total DebtShort + long-term debt | $9.4B | $254M | $249M | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | — | -5.28x | -5.10x | — |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $167 for INO. Over the past 12 months, IMVT leads with a +96.1% total return vs INO's -22.2%. The 3-year compound annual growth rate (CAGR) favors DVAX at 12.4% vs INO's -48.4% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -18.9% | +0.8% | +29.5% | +5.1% |
| 1-Year ReturnPast 12 months | -22.2% | +59.5% | +55.1% | +96.1% |
| 3-Year ReturnCumulative with dividends | -86.2% | +42.1% | +23.9% | +40.9% |
| 5-Year ReturnCumulative with dividends | -98.3% | +58.0% | -94.8% | +62.4% |
| 10-Year ReturnCumulative with dividends | -98.6% | +2.9% | -90.4% | +173.6% |
| CAGR (3Y)Annualised 3-year return | -48.4% | +12.4% | +7.4% | +12.1% |
Risk & Volatility
DVAX leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
DVAX is the less volatile stock with a 0.75 beta — it tends to amplify market swings less than NVAX's 2.11 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. DVAX currently trades 98.5% from its 52-week high vs INO's 46.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.31x | 0.75x | 2.11x | 1.37x |
| 52-Week HighHighest price in past year | $2.98 | $15.73 | $11.97 | $30.09 |
| 52-Week LowLowest price in past year | $1.03 | $9.20 | $5.80 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +46.0% | +98.5% | +77.1% | +90.5% |
| RSI (14)Momentum oscillator 0–100 | 50.9 | 75.7 | 64.4 | 60.2 |
| Avg Volume (50D)Average daily shares traded | 1.9M | 5.7M | 4.4M | 1.4M |
Analyst Outlook
NVAX leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: INO as "Buy", DVAX as "Buy", NVAX as "Buy", IMVT as "Buy". Consensus price targets imply 338.0% upside for INO (target: $6) vs 67.2% for IMVT (target: $46).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $6.00 | $27.00 | $18.00 | $45.50 |
| # AnalystsCovering analysts | 17 | 11 | 23 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | 0 | — | 1 | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +5.5% | +0.3% | 0.0% |
DVAX leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NVAX leads in 2 (Valuation Metrics, Analyst Outlook).
INO vs DVAX vs NVAX vs IMVT: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is INO or DVAX or NVAX or IMVT a better buy right now?
For growth investors, Novavax, Inc.
(NVAX) is the stronger pick with 64. 7% revenue growth year-over-year, versus -100. 0% for Inovio Pharmaceuticals, Inc. (INO). Novavax, Inc. (NVAX) offers the better valuation at 3. 6x trailing P/E, making it the more compelling value choice. Analysts rate Inovio Pharmaceuticals, Inc. (INO) a "Buy" — based on 17 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — INO or DVAX or NVAX or IMVT?
On trailing P/E, Novavax, Inc.
(NVAX) is the cheapest at 3. 6x versus Dynavax Technologies Corporation at 77. 5x.
03Which is the better long-term investment — INO or DVAX or NVAX or IMVT?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +62. 4%, compared to -98. 3% for Inovio Pharmaceuticals, Inc. (INO). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus INO's -98. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — INO or DVAX or NVAX or IMVT?
By beta (market sensitivity over 5 years), Dynavax Technologies Corporation (DVAX) is the lower-risk stock at 0.
75β versus Novavax, Inc. 's 2. 11β — meaning NVAX is approximately 182% more volatile than DVAX relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 43% for Dynavax Technologies Corporation — giving it more financial flexibility in a downturn.
05Which is growing faster — INO or DVAX or NVAX or IMVT?
By revenue growth (latest reported year), Novavax, Inc.
(NVAX) is pulling ahead at 64. 7% versus -100. 0% for Inovio Pharmaceuticals, Inc. (INO). On earnings-per-share growth, the picture is similar: Dynavax Technologies Corporation grew EPS 503. 2% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, NVAX leads at -11. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — INO or DVAX or NVAX or IMVT?
Novavax, Inc.
(NVAX) is the more profitable company, earning 39. 2% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVAX leads at 50. 1% versus -1. 5% for DVAX. At the gross margin level — before operating expenses — NVAX leads at 93. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is INO or DVAX or NVAX or IMVT more undervalued right now?
Analyst consensus price targets imply the most upside for INO: 338.
0% to $6. 00.
08Which pays a better dividend — INO or DVAX or NVAX or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is INO or DVAX or NVAX or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Dynavax Technologies Corporation (DVAX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
75)). Novavax, Inc. (NVAX) carries a higher beta of 2. 11 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (DVAX: +2. 9%, NVAX: -90. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between INO and DVAX and NVAX and IMVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: INO is a small-cap quality compounder stock; DVAX is a small-cap high-growth stock; NVAX is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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