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4 / 10Stock Comparison
XAIR vs NKTR vs AGEN vs NVAX
Revenue, margins, valuation, and 5-year total return — side by side.
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Biotechnology
XAIR vs NKTR vs AGEN vs NVAX — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Devices | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $4M | $1.69B | $132M | $1.50B |
| Revenue (TTM) | $7M | $55M | $114M | $596M |
| Net Income (TTM) | $-31M | $-164M | $115K | $-88M |
| Gross Margin | 1.8% | 99.6% | 35.7% | 84.6% |
| Operating Margin | -419.5% | -237.9% | -17.7% | -11.2% |
| Forward P/E | — | — | 1.8x | 3.6x |
| Total Debt | $12M | $149M | $10M | $249M |
| Cash & Equiv. | $5M | $15M | $3M | $241M |
XAIR vs NKTR vs AGEN vs NVAX — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Beyond Air, Inc. (XAIR) | 100 | 0.3 | -99.7% |
| Nektar Therapeutics (NKTR) | 100 | 25.6 | -74.4% |
| Agenus Inc. (AGEN) | 100 | 5.0 | -95.0% |
| Novavax, Inc. (NVAX) | 100 | 20.0 | -80.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: XAIR vs NKTR vs AGEN vs NVAX
Each card shows where this stock fits in a portfolio — not just who wins on paper.
XAIR is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 0.47, Low D/E 81.5%, current ratio 3.20x
- Beta 0.47, current ratio 3.20x
- 219.7% revenue growth vs NKTR's -43.9%
- Beta 0.47 vs AGEN's 2.72
NKTR is the clearest fit if your priority is long-term compounding.
- -59.1% 10Y total return vs NVAX's -90.4%
- +8.2% vs XAIR's -86.2%
AGEN carries the broadest edge in this set and is the clearest fit for income & stability.
- Dividend streak 1 yrs, beta 2.72
- Lower P/E (1.8x vs 3.6x)
- 0.1% margin vs XAIR's -447.7%
- 0.1% ROA vs XAIR's -84.3%
NVAX is the clearest fit if your priority is growth exposure.
- Rev growth 64.7%, EPS growth 306.5%, 3Y rev CAGR -11.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 219.7% revenue growth vs NKTR's -43.9% | |
| Value | Lower P/E (1.8x vs 3.6x) | |
| Quality / Margins | 0.1% margin vs XAIR's -447.7% | |
| Stability / Safety | Beta 0.47 vs AGEN's 2.72 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +8.2% vs XAIR's -86.2% | |
| Efficiency (ROA) | 0.1% ROA vs XAIR's -84.3% |
XAIR vs NKTR vs AGEN vs NVAX — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
XAIR vs NKTR vs AGEN vs NVAX — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
XAIR leads in 1 of 6 categories
AGEN leads 1 • NKTR leads 1 • NVAX leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — AGEN and NVAX each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVAX is the larger business by revenue, generating $596M annually — 86.1x XAIR's $7M. Profitability is closely matched — net margins range from 0.1% (AGEN) to -4.5% (XAIR). On growth, XAIR holds the edge at +104.7% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $7M | $55M | $114M | $596M |
| EBITDAEarnings before interest/tax | -$25M | -$130M | -$10M | -$47M |
| Net IncomeAfter-tax profit | -$31M | -$164M | $115,000 | -$88M |
| Free Cash FlowCash after capex | -$22M | -$209M | -$159M | -$96M |
| Gross MarginGross profit ÷ Revenue | +1.8% | +99.6% | +35.7% | +84.6% |
| Operating MarginEBIT ÷ Revenue | -4.2% | -2.4% | -17.7% | -11.2% |
| Net MarginNet income ÷ Revenue | -4.5% | -3.0% | +0.1% | -14.7% |
| FCF MarginFCF ÷ Revenue | -3.2% | -3.8% | -139.1% | -16.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +104.7% | -25.3% | +27.5% | -79.1% |
| EPS Growth (YoY)Latest quarter vs prior year | +71.3% | -4.5% | +85.3% | -102.0% |
Valuation Metrics
XAIR leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $4M | $1.7B | $132M | $1.5B |
| Enterprise ValueMkt cap + debt − cash | $11M | $1.8B | $140M | $1.5B |
| Trailing P/EPrice ÷ TTM EPS | -0.04x | -8.57x | -1102.94x | 3.63x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 1.79x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | 2.56x |
| Price / SalesMarket cap ÷ Revenue | 1.13x | 30.64x | 1.16x | 1.34x |
| Price / BookPrice ÷ Book value/share | 0.12x | 15.66x | — | — |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
AGEN leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
XAIR delivers a -3.7% return on equity — every $100 of shareholder capital generates $-4 in annual profit, vs $-4 for NKTR. XAIR carries lower financial leverage with a 0.82x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), AGEN scores 6/9 vs NKTR's 2/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -3.7% | -4.0% | — | — |
| ROA (TTM)Return on assets | -84.3% | -62.8% | +0.1% | -7.4% |
| ROICReturn on invested capital | -121.4% | -57.2% | — | — |
| ROCEReturn on capital employed | -126.4% | -55.7% | — | +100.4% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 2 | 6 | 5 |
| Debt / EquityFinancial leverage | 0.82x | 1.66x | — | — |
| Net DebtTotal debt minus cash | $7M | $134M | $7M | $8M |
| Cash & Equiv.Liquid assets | $5M | $15M | $3M | $241M |
| Total DebtShort + long-term debt | $12M | $149M | $10M | $249M |
| Interest CoverageEBIT ÷ Interest expense | -10.24x | -4.74x | 1.11x | -5.10x |
Total Returns (Dividends Reinvested)
NKTR leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NKTR five years ago would be worth $2,765 today (with dividends reinvested), compared to $48 for XAIR. Over the past 12 months, NKTR leads with a +818.2% total return vs XAIR's -86.2%. The 3-year compound annual growth rate (CAGR) favors NKTR at 93.3% vs XAIR's -83.5% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -37.0% | +92.0% | +16.1% | +29.5% |
| 1-Year ReturnPast 12 months | -86.2% | +818.2% | +27.1% | +55.1% |
| 3-Year ReturnCumulative with dividends | -99.6% | +621.8% | -88.2% | +23.9% |
| 5-Year ReturnCumulative with dividends | -99.5% | -72.3% | -93.9% | -94.8% |
| 10-Year ReturnCumulative with dividends | -99.6% | -59.1% | -94.3% | -90.4% |
| CAGR (3Y)Annualised 3-year return | -83.5% | +93.3% | -51.0% | +7.4% |
Risk & Volatility
Evenly matched — XAIR and NVAX each lead in 1 of 2 comparable metrics.
Risk & Volatility
XAIR is the less volatile stock with a 0.47 beta — it tends to amplify market swings less than AGEN's 2.72 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NVAX currently trades 77.1% from its 52-week high vs XAIR's 8.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.47x | 1.85x | 2.72x | 2.11x |
| 52-Week HighHighest price in past year | $5.84 | $109.00 | $7.34 | $11.97 |
| 52-Week LowLowest price in past year | $0.43 | $7.99 | $2.71 | $5.80 |
| % of 52W HighCurrent price vs 52-week peak | +8.5% | +76.5% | +51.1% | +77.1% |
| RSI (14)Momentum oscillator 0–100 | 45.0 | 53.4 | 48.8 | 64.4 |
| Avg Volume (50D)Average daily shares traded | 254K | 991K | 814K | 4.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: NKTR as "Buy", AGEN as "Buy", NVAX as "Buy". Consensus price targets imply 95.5% upside for AGEN (target: $7) vs 59.3% for NKTR (target: $133).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $132.83 | $7.33 | $18.00 |
| # AnalystsCovering analysts | — | 33 | 11 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | 1 | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.1% | +0.3% |
XAIR leads in 1 of 6 categories (Valuation Metrics). AGEN leads in 1 (Profitability & Efficiency). 2 tied.
XAIR vs NKTR vs AGEN vs NVAX: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is XAIR or NKTR or AGEN or NVAX a better buy right now?
For growth investors, Beyond Air, Inc.
(XAIR) is the stronger pick with 219. 7% revenue growth year-over-year, versus -43. 9% for Nektar Therapeutics (NKTR). Novavax, Inc. (NVAX) offers the better valuation at 3. 6x trailing P/E, making it the more compelling value choice. Analysts rate Nektar Therapeutics (NKTR) a "Buy" — based on 33 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — XAIR or NKTR or AGEN or NVAX?
Over the past 5 years, Nektar Therapeutics (NKTR) delivered a total return of -72.
3%, compared to -99. 5% for Beyond Air, Inc. (XAIR). Over 10 years, the gap is even starker: NKTR returned -59. 1% versus XAIR's -99. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — XAIR or NKTR or AGEN or NVAX?
By beta (market sensitivity over 5 years), Beyond Air, Inc.
(XAIR) is the lower-risk stock at 0. 47β versus Agenus Inc. 's 2. 72β — meaning AGEN is approximately 477% more volatile than XAIR relative to the S&P 500. On balance sheet safety, Beyond Air, Inc. (XAIR) carries a lower debt/equity ratio of 82% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.
04Which is growing faster — XAIR or NKTR or AGEN or NVAX?
By revenue growth (latest reported year), Beyond Air, Inc.
(XAIR) is pulling ahead at 219. 7% versus -43. 9% for Nektar Therapeutics (NKTR). On earnings-per-share growth, the picture is similar: Novavax, Inc. grew EPS 306. 5% year-over-year, compared to -12. 1% for Nektar Therapeutics. Over a 3-year CAGR, AGEN leads at 5. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — XAIR or NKTR or AGEN or NVAX?
Novavax, Inc.
(NVAX) is the more profitable company, earning 39. 2% net margin versus -1258. 4% for Beyond Air, Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVAX leads at 50. 1% versus -1202. 1% for XAIR. At the gross margin level — before operating expenses — NKTR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is XAIR or NKTR or AGEN or NVAX more undervalued right now?
Analyst consensus price targets imply the most upside for AGEN: 95.
5% to $7. 33.
07Which pays a better dividend — XAIR or NKTR or AGEN or NVAX?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is XAIR or NKTR or AGEN or NVAX better for a retirement portfolio?
For long-horizon retirement investors, Beyond Air, Inc.
(XAIR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 47)). Agenus Inc. (AGEN) carries a higher beta of 2. 72 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (XAIR: -99. 6%, AGEN: -94. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between XAIR and NKTR and AGEN and NVAX?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: XAIR is a small-cap high-growth stock; NKTR is a small-cap quality compounder stock; AGEN is a small-cap quality compounder stock; NVAX is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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