Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ACAD held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 42.9M | $954.9M | 0.0% | 25.054% | 5.48% |
| 2 | BlackRock, Inc. | 21.6M | $479.7M | +3.8% | 12.587% | 0.01% |
| 3 | VANGUARD PORTFOLIO MANAGEMENT LLC | 8.7M | $193.0M | — | 5.065% | 0.01% |
| 4 | STATE STREET CORP | 8.3M | $185.5M | +5.3% | 4.867% | 0.01% |
| 5 | RTW INVESTMENTS, LP | 7.1M | $159.0M | 0.0% | 4.173% | 1.58% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 5.7M | $126.0M | — | 3.307% | 0.00% |
| 7 | GEODE CAPITAL MANAGEMENT, LLC | 3.5M | $77.1M | +7.0% | 2.024% | 0.00% |
| 8 | FIRST TRUST ADVISORS LP | 3.3M | $74.4M | +47.3% | 1.953% | 0.05% |
| 9 | DIMENSIONAL FUND ADVISORS LP | 3.2M | $70.2M | +8.0% | 1.843% | 0.01% |
| 10 | Palo Alto Investors LP | 2.9M | $63.9M | +15.7% | 1.678% | 9.78% |
| 11 | Point72 Asset Management, L.P. | 2.6M | $58.0M | -22.9% | 1.522% | 0.08% |
| 12 | BRAIDWELL LP | 2.5M | $55.0M | +21.6% | 1.443% | 1.84% |
| 13 | Pictet Asset Management Holding SA | 2.0M | $44.7M | +31.0% | 1.183% | 0.05% |
| 14 | RENAISSANCE TECHNOLOGIES LLC | 1.7M | $38.4M | +12.5% | 1.007% | 0.06% |
| 15 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1.6M | $34.9M | +4.5% | 0.917% | 0.02% |
| 16 | GOLDMAN SACHS GROUP INC | 1.6M | $34.7M | -0.8% | 0.910% | 0.00% |
| 17 | BANK OF AMERICA CORP /DE/ | 1.6M | $34.6M | +27.2% | 0.907% | 0.00% |
| 18 | Frazier Life Sciences Management, L.P. | 1.4M | $32.0M | +10.9% | 0.840% | 0.82% |
| 19 | Artisan Partners Limited Partnership | 1.3M | $29.6M | — | 0.778% | 0.05% |
| 20 | FRED ALGER MANAGEMENT, LLC | 1.3M | $28.4M | -18.1% | 0.746% | 0.12% |
| 21 | NORTHERN TRUST CORP | 1.3M | $28.3M | +3.0% | 0.743% | 0.00% |
| 22 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.2M | $26.1M | +0.1% | 0.685% | 0.00% |
| 23 | MORGAN STANLEY | 1.1M | $24.3M | -4.3% | 0.638% | 0.00% |
| 24 | Nuveen, LLC | 1.0M | $23.1M | -1.9% | 0.606% | 0.01% |
| 25 | Rockefeller Capital Management L.P. | 1.0M | $22.9M | -7.7% | 0.600% | 0.04% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in ACAD — a direct measure of their conviction.
Filings activity in ACAD during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 333 | +1.2% | 99.88% | 21.65 pp | $3.61B | 18% |
| Q4 2025 | 329 | +1.2% | 121.53% | +23.32 pp | $4.39B | +24% |
| Q3 2025 | 325 | +6.9% | 98.21% | 2.04 pp | $3.55B | 2.0% |
| Q2 2025 | 304 | 2.6% | 100.25% | +22.61 pp | $3.62B | +29% |
| Q1 2025 | 312 | +6.8% | 77.64% | 2.90 pp | $2.80B | 3.6% |
| Q4 2024 | 292 | +16% | 80.54% | +15.59 pp | $2.91B | +24% |
| Q3 2024 | 252 | 3.4% | 64.95% | 5.61 pp | $2.35B | 8.0% |
| Q2 2024 | 261 | — | 70.56% | — | $2.55B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ACAD stock.
Based on Q1 2026 13F filings, institutional ownership of ACADIA Pharmaceuticals Inc. stands at 99.9%, held across 333 reporting institutions.
BAKER BROS. ADVISORS LP is the largest reported institutional holder of ACAD, with approximately 42,896,690 shares worth $0.95B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of ACAD, including Point72 Asset Management, L.P., RENAISSANCE TECHNOLOGIES LLC.
Our composite Smart Money Score for ACAD is 46 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
47 institutions opened new positions in ACAD during Q1 2026, while 43 fully exited. 56 added to existing positions and 227 trimmed.
ACAD institutional ownership fell by 21.65 percentage points quarter-over-quarter, with a net change of +4 holders.
The top 10 institutions account for 66.1% of all reported 13F value in ACAD, and the top 25 account for 80.4%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
ACADIA Pharmaceuticals Inc. (ACAD) Institutional Ownership