Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ACIU held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BVF INC/IL | 19.8M | $54.5M | 0.0% | 19.477% | 1.74% |
| 2 | WELLS FARGO & COMPANY/MN | 1.0M | $2.8M | -0.2% | 0.987% | 0.00% |
| 3 | MILLENNIUM MANAGEMENT LLC | 793K | $2.2M | -15.1% | 0.779% | 0.00% |
| 4 | RENAISSANCE TECHNOLOGIES LLC | 624K | $1.7M | -6.7% | 0.613% | 0.00% |
| 5 | BlackRock, Inc. | 524K | $1.4M | +4.4% | 0.515% | 0.00% |
| 6 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 406K | $1.1M | +8.0% | 0.399% | 0.00% |
| 7 | DIMENSIONAL FUND ADVISORS LP | 390K | $1.1M | +82.8% | 0.383% | 0.00% |
| 8 | CITADEL ADVISORS LLC | 298K | $820K | +124.2% | 0.293% | 0.00% |
| 9 | NORTHERN TRUST CORP | 279K | $766K | -1.2% | 0.274% | 0.00% |
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 158K | $434K | -15.2% | 0.155% | 0.00% |
| 11 | MARSHALL WACE, LLP | 131K | $362K | -29.6% | 0.129% | 0.00% |
| 12 | Dauntless Investment Group, LLC | 107K | $296K | -7.1% | 0.106% | 0.79% |
| 13 | UBS Group AG | 102K | $279K | -47.7% | 0.100% | 0.00% |
| 14 | MORGAN STANLEY | 89K | $245K | -5.4% | 0.088% | 0.00% |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 64K | $175K | 0.0% | 0.063% | 0.00% |
| 16 | JANE STREET GROUP, LLC | 58K | $159K | +35.4% | 0.057% | 0.00% |
| 17 | TWO SIGMA INVESTMENTS, LP | 39K | $108K | -55.5% | 0.038% | 0.00% |
| 18 | GOLDMAN SACHS GROUP INC | 22K | $59K | +16.6% | 0.021% | 0.00% |
| 19 | China Universal Asset Management Co., Ltd. | 18K | $49K | +9.1% | 0.017% | 0.00% |
| 20 | BANK OF AMERICA CORP /DE/ | 17K | $48K | -18.8% | 0.017% | 0.00% |
| 21 | XTX Topco Ltd | 14K | $39K | — | 0.014% | 0.00% |
| 22 | Jump Financial, LLC | 11K | $31K | — | 0.011% | 0.00% |
| 23 | Quinn Opportunity Partners LLC | 10K | $28K | 0.0% | 0.010% | 0.00% |
| 24 | Silverberg Bernstein Capital Management LLC | 10K | $28K | 0.0% | 0.010% | 0.02% |
| 25 | EFG International AG | 10K | $27K | -23.3% | 0.010% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in ACIU — a direct measure of their conviction.
Filings activity in ACIU during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 45 | +9.8% | 29.29% | 4.73 pp | $69M | 14% |
| Q4 2025 | 41 | +5.1% | 34.02% | +5.36 pp | $80M | +19% |
| Q3 2025 | 39 | 7.1% | 28.66% | +7.95 pp | $67M | +38% |
| Q2 2025 | 42 | +2.4% | 20.71% | +0.66 pp | $49M | +3.3% |
| Q1 2025 | 41 | 8.9% | 20.05% | 10.97 pp | $47M | 35% |
| Q4 2024 | 45 | +4.7% | 31.02% | 13.94 pp | $73M | 31% |
| Q3 2024 | 43 | 4.4% | 44.96% | 3.18 pp | $106M | 6.6% |
| Q2 2024 | 45 | — | 48.14% | — | $113M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ACIU stock.
Based on Q1 2026 13F filings, institutional ownership of AC Immune S.A. stands at 29.3%, held across 45 reporting institutions.
BVF INC/IL is the largest reported institutional holder of ACIU, with approximately 19,822,436 shares worth $0.05B as of Q1 2026.
Yes — 6 widely-followed marquee investors appear among the top 25 institutional holders of ACIU, including MILLENNIUM MANAGEMENT LLC, RENAISSANCE TECHNOLOGIES LLC, CITADEL ADVISORS LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP, JANE STREET GROUP, LLC.
Our composite Smart Money Score for ACIU is 61 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
9 institutions opened new positions in ACIU during Q1 2026, while 5 fully exited. 5 added to existing positions and 30 trimmed.
ACIU institutional ownership fell by 4.73 percentage points quarter-over-quarter, with a net change of +4 holders.
The top 10 institutions account for 97.0% of all reported 13F value in ACIU, and the top 25 account for 99.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
AC Immune S.A. (ACIU) Institutional Ownership