Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in AGEN held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | VANGUARD CAPITAL MANAGEMENT LLC | 1.4M | $4.8M | — | 3.459% | 0.00% |
| 2 | VANGUARD PORTFOLIO MANAGEMENT LLC | 1.2M | $4.0M | — | 2.870% | 0.00% |
| 3 | Siren, L.L.C. | 1.1M | $3.6M | 0.0% | 2.556% | 0.10% |
| 4 | MARSHALL WACE, LLP | 688K | $2.3M | +368.8% | 1.653% | 0.00% |
| 5 | BlackRock, Inc. | 546K | $1.8M | -2.3% | 1.310% | 0.00% |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 348K | $1.2M | -6.5% | 0.837% | 0.00% |
| 7 | MORGAN STANLEY | 296K | $988K | +3.7% | 0.710% | 0.00% |
| 8 | RENAISSANCE TECHNOLOGIES LLC | 286K | $954K | -47.4% | 0.686% | 0.00% |
| 9 | Man Group plc | 279K | $932K | +144.3% | 0.670% | 0.00% |
| 10 | RAYMOND JAMES FINANCIAL INC | 240K | $800K | +69.1% | 0.575% | 0.00% |
| 11 | UBS Group AG | 234K | $783K | +97.3% | 0.563% | 0.00% |
| 12 | VANGUARD FIDUCIARY TRUST CO | 200K | $670K | — | 0.481% | 0.00% |
| 13 | Connor, Clark & Lunn Investment Management Ltd. | 199K | $663K | +192.1% | 0.477% | 0.00% |
| 14 | TWO SIGMA INVESTMENTS, LP | 171K | $571K | +45.9% | 0.411% | 0.00% |
| 15 | PANAGORA ASSET MANAGEMENT INC | 163K | $545K | 0.0% | 0.392% | 0.00% |
| 16 | Jump Financial, LLC | 157K | $525K | -7.8% | 0.378% | 0.01% |
| 17 | STATE STREET CORP | 156K | $522K | +13.7% | 0.375% | 0.00% |
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 135K | $450K | -52.5% | 0.324% | 0.00% |
| 19 | CITADEL ADVISORS LLC | 130K | $433K | -75.2% | 0.311% | 0.00% |
| 20 | Walleye Capital LLC | 121K | $403K | -2.3% | 0.289% | 0.00% |
| 21 | BANK OF AMERICA CORP /DE/ | 119K | $397K | +796.7% | 0.285% | 0.00% |
| 22 | 683 Capital Management, LLC | 114K | $382K | 0.0% | 0.275% | 0.03% |
| 23 | NORTHERN TRUST CORP | 90K | $300K | +0.1% | 0.215% | 0.00% |
| 24 | BARCLAYS PLC | 59K | $198K | +28.2% | 0.143% | 0.00% |
| 25 | CANADA PENSION PLAN INVESTMENT BOARD | 52K | $173K | -21.6% | 0.124% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in AGEN — a direct measure of their conviction.
Filings activity in AGEN during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 88 | 7.4% | 22.23% | 25.47 pp | $31M | 53% |
| Q4 2025 | 95 | +13% | 47.70% | +23.32 pp | $66M | +96% |
| Q3 2025 | 84 | 7.7% | 24.38% | 3.62 pp | $33M | 13% |
| Q2 2025 | 91 | +5.8% | 28.00% | +18.70 pp | $38M | +201% |
| Q1 2025 | 86 | +2.4% | 9.30% | 11.22 pp | $13M | 55% |
| Q4 2024 | 84 | 12% | 20.52% | 13.75 pp | $28M | 40% |
| Q3 2024 | 95 | +5.6% | 34.27% | 73.63 pp | $47M | 68% |
| Q2 2024 | 90 | — | 107.90% | — | $148M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying AGEN stock.
Based on Q1 2026 13F filings, institutional ownership of Agenus Inc. stands at 22.2%, held across 88 reporting institutions.
VANGUARD CAPITAL MANAGEMENT LLC is the largest reported institutional holder of AGEN, with approximately 1,440,232 shares worth $0.00B as of Q1 2026.
Yes — 4 widely-followed marquee investors appear among the top 25 institutional holders of AGEN, including RENAISSANCE TECHNOLOGIES LLC, TWO SIGMA INVESTMENTS, LP, SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC.
Our composite Smart Money Score for AGEN is 44 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
17 institutions opened new positions in AGEN during Q1 2026, while 24 fully exited. 47 added to existing positions and 22 trimmed.
AGEN institutional ownership fell by 25.47 percentage points quarter-over-quarter, with a net change of -7 holders.
The top 10 institutions account for 69.8% of all reported 13F value in AGEN, and the top 25 account for 92.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Agenus Inc. (AGEN) Institutional Ownership