Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ANVS held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | MARSHALL WACE, LLP | 1.2M | $2.6M | +63.6% | 6.036% | 0.00% |
| 2 | VANGUARD CAPITAL MANAGEMENT LLC | 872K | $1.9M | β | 4.434% | 0.00% |
| 3 | TWO SIGMA INVESTMENTS, LP | 628K | $1.4M | +13.7% | 3.190% | 0.00% |
| 4 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 541K | $1.2M | -8.4% | 2.750% | 0.00% |
| 5 | RENAISSANCE TECHNOLOGIES LLC | 348K | $775K | β | 1.767% | 0.00% |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 248K | $552K | +11.4% | 1.258% | 0.00% |
| 7 | NORTHERN TRUST CORP | 142K | $316K | +17.3% | 0.720% | 0.00% |
| 8 | BlackRock, Inc. | 140K | $311K | 0.0% | 0.709% | 0.00% |
| 9 | VANGUARD FIDUCIARY TRUST CO | 132K | $294K | β | 0.671% | 0.00% |
| 10 | Merit Financial Group, LLC | 81K | $181K | 0.0% | 0.413% | 0.00% |
| 11 | STATE STREET CORP | 78K | $173K | +5.0% | 0.395% | 0.00% |
| 12 | GROUP ONE TRADING, L.P. | 70K | $155K | +0.8% | 0.354% | 0.01% |
| 13 | Sherry Group, Inc. | 57K | $128K | +110.0% | 0.291% | 0.14% |
| 14 | Wescott Financial Advisory Group, LLC | 42K | $93K | 0.0% | 0.212% | 0.01% |
| 15 | FIRST NATIONAL TRUST CO | 40K | $89K | 0.0% | 0.203% | 0.00% |
| 16 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 38K | $84K | +54.4% | 0.192% | 0.00% |
| 17 | Dakota Wealth Management | 26K | $58K | -0.8% | 0.132% | 0.00% |
| 18 | XTX Topco Ltd | 25K | $55K | β | 0.125% | 0.00% |
| 19 | Sterling Investment Advisors, Ltd. | 23K | $52K | 0.0% | 0.119% | 0.01% |
| 20 | UBS Group AG | 22K | $48K | -29.7% | 0.110% | 0.00% |
| 21 | Wealthspire Advisors, LLC | 20K | $45K | 0.0% | 0.102% | 0.00% |
| 22 | GILL CAPITAL PARTNERS, LLC | 19K | $41K | 0.0% | 0.094% | 0.01% |
| 23 | Robertson Stephens Wealth Management, LLC | 19K | $41K | 0.0% | 0.094% | 0.00% |
| 24 | CWA Asset Management Group, LLC | 17K | $38K | 0.0% | 0.086% | 0.00% |
| 25 | Gallacher Capital Management LLC | 16K | $35K | β | 0.080% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in ANVS β a direct measure of their conviction.
Filings activity in ANVS during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 55 | +3.8% | 31.35% | 14.16 pp | $11M | 31% |
| Q4 2025 | 53 | +36% | 45.51% | +34.58 pp | $16M | +316% |
| Q3 2025 | 39 | 7.1% | 10.93% | 0.40 pp | $4M | 3.6% |
| Q2 2025 | 42 | 6.7% | 11.33% | +2.25 pp | $4M | +25% |
| Q1 2025 | 45 | +13% | 9.08% | 17.32 pp | $3M | 66% |
| Q4 2024 | 40 | +14% | 26.40% | 5.38 pp | $9M | 17% |
| Q3 2024 | 35 | +17% | 31.78% | +16.13 pp | $11M | +103% |
| Q2 2024 | 30 | β | 15.65% | β | $5M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ANVS stock.
Based on Q1 2026 13F filings, institutional ownership of Annovis Bio, Inc. stands at 31.4%, held across 55 reporting institutions.
MARSHALL WACE, LLP is the largest reported institutional holder of ANVS, with approximately 1,187,499 shares worth $0.00B as of Q1 2026.
Yes β 3 widely-followed marquee investors appear among the top 25 institutional holders of ANVS, including TWO SIGMA INVESTMENTS, LP, SUSQUEHANNA INTERNATIONAL GROUP, LLP, RENAISSANCE TECHNOLOGIES LLC.
Our composite Smart Money Score for ANVS is 52 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
14 institutions opened new positions in ANVS during Q1 2026, while 12 fully exited. 4 added to existing positions and 36 trimmed.
ANVS institutional ownership fell by 14.16 percentage points quarter-over-quarter, with a net change of +2 holders.
The top 10 institutions account for 87.7% of all reported 13F value in ANVS, and the top 25 account for 98.1%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Annovis Bio, Inc. (ANVS) Institutional Ownership