Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in AVXL held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 7.6M | $23.4M | +1.1% | 8.211% | 0.00% |
| 2 | STATE STREET CORP | 4.5M | $13.9M | +2.9% | 4.869% | 0.00% |
| 3 | VANGUARD CAPITAL MANAGEMENT LLC | 3.9M | $11.9M | — | 4.170% | 0.00% |
| 4 | TWO SIGMA INVESTMENTS, LP | 3.2M | $10.0M | +96.4% | 3.505% | 0.01% |
| 5 | GEODE CAPITAL MANAGEMENT, LLC | 2.2M | $6.7M | +8.2% | 2.361% | 0.00% |
| 6 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.5M | $4.7M | +11.5% | 1.661% | 0.00% |
| 7 | CITADEL ADVISORS LLC | 1.2M | $3.6M | +12.4% | 1.265% | 0.00% |
| 8 | Summit Financial, LLC | 940K | $2.9M | +4.1% | 1.015% | 0.04% |
| 9 | BANK OF AMERICA CORP /DE/ | 863K | $2.6M | +64.7% | 0.931% | 0.00% |
| 10 | GOLDMAN SACHS GROUP INC | 804K | $2.5M | -7.8% | 0.868% | 0.00% |
| 11 | VANGUARD PORTFOLIO MANAGEMENT LLC | 783K | $2.4M | — | 0.845% | 0.00% |
| 12 | AQR CAPITAL MANAGEMENT LLC | 757K | $2.3M | +405.1% | 0.817% | 0.00% |
| 13 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 757K | $2.3M | +13.1% | 0.816% | 0.00% |
| 14 | NORTHERN TRUST CORP | 725K | $2.2M | -1.8% | 0.783% | 0.00% |
| 15 | JANE STREET GROUP, LLC | 725K | $2.2M | -15.7% | 0.782% | 0.02% |
| 16 | VANGUARD FIDUCIARY TRUST CO | 647K | $2.0M | — | 0.698% | 0.00% |
| 17 | UBS Group AG | 570K | $1.7M | +24.1% | 0.615% | 0.00% |
| 18 | BARCLAYS PLC | 538K | $1.7M | +9.2% | 0.581% | 0.00% |
| 19 | FEDERATED HERMES, INC. | 532K | $1.6M | +44.7% | 0.574% | 0.00% |
| 20 | Private Advisor Group, LLC | 500K | $1.5M | +19.0% | 0.539% | 0.01% |
| 21 | MARSHALL WACE, LLP | 419K | $1.3M | +130.3% | 0.453% | 0.00% |
| 22 | LPL Financial LLC | 419K | $1.3M | -20.8% | 0.452% | 0.00% |
| 23 | MORGAN STANLEY | 358K | $1.1M | -24.7% | 0.386% | 0.00% |
| 24 | RENAISSANCE TECHNOLOGIES LLC | 277K | $850K | +988.8% | 0.299% | 0.00% |
| 25 | XTX Topco Ltd | 258K | $792K | +160.5% | 0.279% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in AVXL — a direct measure of their conviction.
Filings activity in AVXL during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 187 | +2.7% | 53.18% | 35.56 pp | $123M | 40% |
| Q4 2025 | 182 | +1.1% | 88.74% | 45.90 pp | $206M | 34% |
| Q3 2025 | 180 | +2.3% | 134.64% | +3.05 pp | $312M | +2.3% |
| Q2 2025 | 176 | 2.8% | 131.59% | +14.88 pp | $305M | +13% |
| Q1 2025 | 181 | +7.1% | 116.71% | 19.55 pp | $270M | 14% |
| Q4 2024 | 169 | +17% | 136.26% | +67.66 pp | $316M | +99% |
| Q3 2024 | 144 | +2.9% | 68.60% | +17.75 pp | $159M | +35% |
| Q2 2024 | 140 | — | 50.85% | — | $118M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying AVXL stock.
Based on Q1 2026 13F filings, institutional ownership of Anavex Life Sciences Corp. stands at 53.2%, held across 187 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of AVXL, with approximately 7,609,618 shares worth $0.02B as of Q1 2026.
Yes — 5 widely-followed marquee investors appear among the top 25 institutional holders of AVXL, including TWO SIGMA INVESTMENTS, LP, SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC, JANE STREET GROUP, LLC, RENAISSANCE TECHNOLOGIES LLC.
Our composite Smart Money Score for AVXL is 58 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
39 institutions opened new positions in AVXL during Q1 2026, while 34 fully exited. 43 added to existing positions and 101 trimmed.
AVXL institutional ownership fell by 35.56 percentage points quarter-over-quarter, with a net change of +5 holders.
The top 10 institutions account for 66.6% of all reported 13F value in AVXL, and the top 25 account for 87.2%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Anavex Life Sciences Corp. (AVXL) Institutional Ownership