| 4 | Long Focus Capital Management, LLC | 3.3M | $14.0M | 0.0% | 4.771% | 0.36% |
| 5 | RENAISSANCE TECHNOLOGIES LLC | 1.5M | $6.5M | +56.6% | 2.210% | 0.01% |
| 6 | GSK plc | 1.5M | $6.5M | 0.0% | 2.204% | 1.08% |
| 7 | MARSHALL WACE, LLP | 798K | $3.4M | +111.5% | 1.150% | 0.00% |
| 8 | Qube Research & Technologies Ltd | 776K | $3.3M | +151.3% | 1.118% | 0.00% |
| 9 | MORGAN STANLEY | 667K | $2.8M | +7.9% | 0.962% | 0.00% |
| 10 | CITADEL ADVISORS LLC | 628K | $2.7M | +52.8% | 0.905% | 0.00% |
| 11 | SCHRODER INVESTMENT MANAGEMENT GROUP | 616K | $2.6M | 0.0% | 0.887% | 0.00% |
| 12 | MILLENNIUM MANAGEMENT LLC | 554K | $2.3M | +95.1% | 0.798% | 0.00% |
| 13 | Peapod Lane Capital LLC | 538K | $2.3M | +344.2% | 0.775% | 1.54% |
| 14 | DIADEMA PARTNERS LP | 463K | $2.0M | -2.9% | 0.667% | 0.25% |
| 15 | JANE STREET GROUP, LLC | 455K | $1.9M | +50.1% | 0.655% | 0.00% |
| 16 | TWO SIGMA INVESTMENTS, LP | 435K | $1.8M | +163.7% | 0.626% | 0.00% |
| 17 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 352K | $1.5M | +18.7% | 0.508% | 0.00% |
| 18 | Birchview Capital, LP | 314K | $1.3M | -32.4% | 0.452% | 0.62% |
| 19 | BlackRock, Inc. | 280K | $1.2M | +0.5% | 0.404% | 0.00% |
| 20 | MOORE CAPITAL MANAGEMENT, LP | 275K | $1.2M | 0.0% | 0.396% | 0.02% |
| 21 | Rangeley Capital, LLC | 254K | $1.1M | +9.1% | 0.365% | 0.98% |
| 22 | Palo Alto Investors LP | 202K | $856K | 0.0% | 0.291% | 0.04% |
| 23 | Sculptor Capital LP | 198K | $839K | — | 0.285% | 0.01% |
| 24 | Eversept Partners, LP | 191K | $809K | 0.0% | 0.275% | 0.04% |
| 25 | PINNACLE ASSOCIATES LTD | 190K | $806K | +2.5% | 0.274% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in BCYC — a direct measure of their conviction.
| 60.48% |
| 0.33 pp |
| $325M |
| 40% |
| Q4 2024 | 98 | 5.8% | 60.81% | +2.76 pp | $541M | 34% |
| Q3 2024 | 104 | — | 58.05% | — | $822M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
18 institutions opened new positions in BCYC during Q2 2026, while 12 fully exited. 27 added to existing positions and 57 trimmed.
BCYC institutional ownership fell by 0.26 percentage points quarter-over-quarter, with a net change of +6 holders.
The top 10 institutions account for 77.8% of all reported 13F value in BCYC, and the top 25 account for 93.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Bicycle Therapeutics plc (BCYC) Institutional Ownership