| 4 | TANG CAPITAL MANAGEMENT LLC | 5.0M | $70.8M | +24.9% | 3.706% | 3.21% |
| 5 | TWO SIGMA INVESTMENTS, LP | 4.5M | $63.3M | +73.0% | 3.313% | 0.05% |
| 6 | MARSHALL WACE, LLP | 4.3M | $61.3M | +7.2% | 3.208% | 0.05% |
| 7 | ARK Investment Management LLC | 3.5M | $48.8M | +4.6% | 2.558% | 0.32% |
| 8 | Caption Management, LLC | 2.9M | $41.2M | -19.4% | 2.158% | 0.19% |
| 9 | Point72 Asset Management, L.P. | 2.6M | $37.1M | +11005.4% | 1.943% | 0.04% |
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2.5M | $34.9M | -27.1% | 1.830% | 0.00% |
| 11 | Logos Global Management LP | 2.3M | $31.8M | — | 1.668% | 1.37% |
| 12 | Eagle Health Investments LP | 2.1M | $29.2M | 0.0% | 1.527% | 4.83% |
| 13 | BANK OF AMERICA CORP /DE/ | 2.0M | $28.6M | +6145.7% | 1.497% | 0.00% |
| 14 | DAFNA Capital Management LLC | 2.0M | $28.5M | -16.8% | 1.491% | 5.43% |
| 15 | NEXTBio Capital Management LP | 1.8M | $25.1M | -12.2% | 1.316% | 11.56% |
| 16 | CITADEL ADVISORS LLC | 1.7M | $24.5M | +188.1% | 1.282% | 0.00% |
| 17 | UBS Group AG | 1.5M | $21.0M | -20.1% | 1.099% | 0.00% |
| 18 | Aisling Capital Management LP | 1.4M | $20.3M | 0.0% | 1.062% | 4.30% |
| 19 | RENAISSANCE TECHNOLOGIES LLC | 1.4M | $20.3M | +65.5% | 1.061% | 0.03% |
| 20 | Candriam S.C.A. | 1.3M | $18.0M | — | 0.944% | 0.08% |
| 21 | Woodline Partners LP | 1.1M | $15.4M | +519.0% | 0.805% | 0.05% |
| 22 | Jefferies Financial Group Inc. | 994K | $14.1M | -32.2% | 0.737% | 0.09% |
| 23 | BlackRock, Inc. | 925K | $13.1M | +35.4% | 0.686% | 0.00% |
| 24 | Trexquant Investment LP | 860K | $12.2M | +178.1% | 0.637% | 0.07% |
| 25 | JANE STREET GROUP, LLC | 855K | $12.1M | +76.2% | 0.634% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in CMPS — a direct measure of their conviction.
| 55.33% |
| +11.95 pp |
| $144M |
| +31% |
| Q4 2024 | 127 | +0.8% | 43.38% | +2.39 pp | $110M | 36% |
| Q3 2024 | 126 | — | 40.99% | — | $174M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
59 institutions opened new positions in CMPS during Q2 2026, while 30 fully exited. 145 added to existing positions and 14 trimmed.
CMPS institutional ownership fell by 1.13 percentage points quarter-over-quarter, with a net change of +31 holders.
The top 10 institutions account for 56.8% of all reported 13F value in CMPS, and the top 25 account for 80.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
COMPASS Pathways plc (CMPS) Institutional Ownership