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Crinetics Pharmaceuticals, Inc. (CRNX) Earnings History

Annual and quarterly earnings data from 2016 to 2025

TTM Net Income
-$465M
Net Loss
TTM EPS
$-4.95
Diluted
YoY EPS Growth
-0.3%
Slow
Net Margin
-85.9%
Profitability
Operating Margin-95.3%
Gross Margin0.8%
ROE-0.4%
ROA-0.4%
Highest Annual Net Income-$6M (2016)
Highest Quarterly EPS$-0.18 (Q4 2017)
Consecutive Profitable Years0 years
Q4 2025
Net Income-$123M
EPS$-1.30
QoQ Growth+5.6%Solid

Loading earnings history...

EPS Growth Rates (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
N/A
N/M
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
202580.1%-9534.5%-8585.2%
2024100.0%-32613.5%-28720.7%
2023100.0%-5547.2%-5345.9%
2022100.0%-3544.1%-3460.4%
2021100.0%-9990.9%-9985.3%
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Crinetics Pharmaceuticals, Inc. (CRNX) Earnings Overview

As of March 2, 2026, Crinetics Pharmaceuticals, Inc. (CRNX) reported trailing twelve-month net income of -$465M, reflecting -0.3% year-over-year growth. The company earned $-4.95 per diluted share over the past four quarters, with a net profit margin of -85.9%.

Looking at the long-term picture, CRNX's historical earnings data spans multiple years. The company achieved its highest annual net income of -$6M in fiscal 2016.

Crinetics Pharmaceuticals, Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to industry peers including AGIO (-$401M net income, -7.6% margin), VRTX ($3.68B net income, 0.3% margin), ASND (-$228M net income, -0.3% margin), CRNX has room to improve margins relative to the peer group. Compare CRNX vs AGIO →

Peer Comparison

Earnings metrics vs industry competitors

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
CRNXCurrent
-$465M$-4.95-85.9%-0.4%-0.3%—
AGIO
-$401M$-6.90-7.6%-0.3%-1.6%
VRTX
$3.7B$14.270.3%0.2%+8.4%
ASND
-$228M$-3.71-0.3%-+0.4%
BBIO
-$729M$-3.70-1.5%--0.3%
BMRN
$349M$1.770.1%0.1%+11.9%
Best in group
Lowest in group

Historical Data

10 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$465M-55.9%-$517M$-4.95-8585.2%-9534.5%
2024-$298M-39.1%-$339M$-3.69-28720.7%-32613.5%
2023-$215M-30.9%-$223M$-3.69-5345.9%-5547.2%
2022-$164M-52.3%-$168M$-3.15-3460.4%-3544.1%
2021-$108M-45.8%-$108M$-2.80-9985.3%-9990.9%
2020-$74M-49.0%-$75M$-2.42-103960.6%-105567.6%
2019-$50M-82.7%-$54M$-2.05-4152.1%-4512.3%
2018-$27M-196.1%-$29M$-2.23-1116.8%-1182.5%
2017-$9M-52.1%-$9M$-0.66-447.8%-446.3%
2016-$6M--$6M$-0.43-1021.9%-1026.1%

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Compare CRNX vs AGIO

See how CRNX stacks up against sector leader Agios Pharmaceuticals, Inc..

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Frequently Asked Questions

Is CRNX growing earnings?

CRNX EPS of $-4.95 reflects slowing growth at -0.3%, below the 5-year CAGR of N/A. TTM net income is $-465M. Expansion rate has moderated.

What are CRNX's profit margins?

Crinetics Pharmaceuticals, Inc. net margin is -85.9%, with operating margin at -95.3%. Below-average margins reflect competitive or cost pressures.

How consistent are CRNX's earnings?

CRNX earnings data spans 2016-2025. The current earnings trend is -0.3% YoY. Historical data enables comparison across business cycles.

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Earnings Over Time

Net income and EPS trends