Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in CRNX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 15.8M | $572.4M | +10.3% | 14.947% | 0.03% |
| 2 | BlackRock, Inc. | 8.5M | $308.0M | +6.1% | 8.041% | 0.01% |
| 3 | FARALLON CAPITAL MANAGEMENT LLC | 8.3M | $302.8M | +20.3% | 7.908% | 1.97% |
| 4 | WELLINGTON MANAGEMENT GROUP LLP | 8.2M | $296.3M | +1.5% | 7.736% | 0.06% |
| 5 | DRIEHAUS CAPITAL MANAGEMENT LLC | 6.4M | $232.3M | +0.1% | 6.066% | 1.71% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 4.7M | $169.8M | β | 4.433% | 0.00% |
| 7 | VANGUARD PORTFOLIO MANAGEMENT LLC | 4.6M | $168.5M | β | 4.399% | 0.01% |
| 8 | JANUS HENDERSON GROUP PLC | 4.5M | $164.2M | +1.8% | 4.287% | 0.08% |
| 9 | EcoR1 Capital, LLC | 4.3M | $155.7M | 0.0% | 4.067% | 6.61% |
| 10 | Bellevue Group AG | 3.3M | $119.1M | +81088.1% | 3.111% | 2.84% |
| 11 | GEODE CAPITAL MANAGEMENT, LLC | 2.5M | $90.1M | +10.6% | 2.353% | 0.01% |
| 12 | STATE STREET CORP | 2.4M | $87.3M | +11.2% | 2.279% | 0.00% |
| 13 | BAKER BROS. ADVISORS LP | 2.4M | $85.4M | +42.6% | 2.230% | 0.49% |
| 14 | Siren, L.L.C. | 1.9M | $69.1M | +26.3% | 1.805% | 1.92% |
| 15 | Pictet Asset Management Holding SA | 1.9M | $68.2M | +20.8% | 1.787% | 0.07% |
| 16 | BNP Paribas Asset Management Holding S.A. | 1.7M | $62.3M | +29.3% | 1.628% | 0.07% |
| 17 | Novo Holdings A/S | 1.6M | $56.3M | -4.6% | 1.470% | 4.56% |
| 18 | RTW INVESTMENTS, LP | 1.5M | $52.7M | +7.4% | 1.376% | 0.52% |
| 19 | ADAR1 Capital Management, LLC | 1.1M | $41.4M | +268.3% | 1.081% | 2.59% |
| 20 | First Light Asset Management, LLC | 1.1M | $39.6M | -8.8% | 1.034% | 3.55% |
| 21 | AMERICAN CENTURY COMPANIES INC | 1.1M | $38.2M | -1.5% | 0.999% | 0.02% |
| 22 | SUVRETTA CAPITAL MANAGEMENT, LLC | 1.0M | $37.9M | β | 0.990% | 1.03% |
| 23 | ORBIMED ADVISORS LLC | 999K | $36.3M | 0.0% | 0.948% | 0.76% |
| 24 | MORGAN STANLEY | 920K | $33.4M | +19.6% | 0.872% | 0.00% |
| 25 | Hood River Capital Management LLC | 907K | $33.0M | +1.1% | 0.861% | 0.33% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in CRNX β a direct measure of their conviction.
Filings activity in CRNX during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new CRNX position in Q1 2026
Institutions that fully closed their CRNX position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 239 | +0.0% | 112.33% | 20.66 pp | $4.08B | 16% |
| Q4 2025 | 239 | +9.1% | 132.99% | +16.70 pp | $4.83B | +14% |
| Q3 2025 | 219 | 0.9% | 116.29% | +40.30 pp | $4.23B | +53% |
| Q2 2025 | 221 | +0.0% | 75.99% | 10.27 pp | $2.76B | 12% |
| Q1 2025 | 221 | 9.1% | 86.26% | 40.17 pp | $3.14B | 32% |
| Q4 2024 | 243 | +6.6% | 126.43% | +20.75 pp | $4.60B | +20% |
| Q3 2024 | 228 | 0.4% | 105.68% | +15.17 pp | $3.84B | +17% |
| Q2 2024 | 229 | β | 90.51% | β | $3.29B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying CRNX stock.
Based on Q1 2026 13F filings, institutional ownership of Crinetics Pharmaceuticals, Inc. stands at 112.3%, held across 239 reporting institutions.
FMR LLC is the largest reported institutional holder of CRNX, with approximately 15,759,799 shares worth $0.57B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of CRNX.
Our composite Smart Money Score for CRNX is 27 out of 100 (Bearish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
47 institutions opened new positions in CRNX during Q1 2026, while 47 fully exited. 38 added to existing positions and 152 trimmed.
CRNX institutional ownership fell by 20.66 percentage points quarter-over-quarter, with a net change of +0 holders.
The top 10 institutions account for 61.0% of all reported 13F value in CRNX, and the top 25 account for 81.3%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.