Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in CYTK held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 20.1M | $1.71B | +21.4% | 16.149% | 0.03% |
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 6.9M | $590.5M | -13.5% | 5.571% | 0.10% |
| 3 | VANGUARD PORTFOLIO MANAGEMENT LLC | 6.7M | $571.8M | +14.8% | 5.394% | 0.03% |
| 4 | STATE STREET CORP | 6.5M | $553.2M | +13.0% | 5.219% | 0.01% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 6.1M | $521.2M | +11.5% | 4.916% | 0.01% |
| 6 | FMR LLC | 5.0M | $428.7M | -53.1% | 4.044% | 0.02% |
| 7 | Avoro Capital Advisors LLC | 5.0M | $425.9M | +50.0% | 4.018% | 3.82% |
| 8 | BANK OF AMERICA CORP /DE/ | 4.6M | $394.9M | +48.3% | 3.726% | 0.03% |
| 9 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 3.7M | $317.7M | +67.8% | 2.997% | 0.02% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 3.7M | $316.3M | +15.5% | 2.984% | 0.02% |
| 11 | RTW INVESTMENTS, LP | 2.9M | $243.8M | +5.2% | 2.300% | 2.08% |
| 12 | ARMISTICE CAPITAL, LLC | 2.7M | $232.7M | +2.5% | 2.195% | 2.85% |
| 13 | Polar Capital Holdings Plc | 2.3M | $192.0M | +35.7% | 1.811% | 0.45% |
| 14 | CITADEL ADVISORS LLC | 2.0M | $167.5M | +26.5% | 1.581% | 0.01% |
| 15 | GOLDMAN SACHS GROUP INC | 1.8M | $152.9M | -26.9% | 1.442% | 0.01% |
| 16 | Capital Research Global Investors | 1.7M | $143.7M | +118.8% | 1.355% | 0.02% |
| 17 | NORTHERN TRUST CORP | 1.6M | $140.3M | +14.3% | 1.324% | 0.02% |
| 18 | JPMORGAN CHASE & CO | 1.6M | $139.2M | +75.8% | 1.277% | 0.01% |
| 19 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1.6M | $136.6M | +47.4% | 1.289% | 0.41% |
| 20 | Integral Health Asset Management, LLC | 1.6M | $136.3M | -38.5% | 1.286% | 5.38% |
| 21 | Point72 Asset Management, L.P. | 1.6M | $135.3M | +140.3% | 1.276% | 0.15% |
| 22 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.6M | $133.4M | +12.1% | 1.258% | 0.02% |
| 23 | MORGAN STANLEY | 1.5M | $128.7M | +0.4% | 1.214% | 0.01% |
| 24 | PRINCIPAL FINANCIAL GROUP INC | 1.3M | $111.7M | +20.0% | 1.054% | 0.05% |
| 25 | Capital International Investors | 1.3M | $111.2M | -2.5% | 1.049% | 0.02% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in CYTK — a direct measure of their conviction.
Filings activity in CYTK during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 486 | +8.7% | 134.79% | +8.96 pp | $12.36B | +38% |
| Q1 2026 | 447 | +4.0% | 125.83% | +14.29 pp | $8.98B | +8.0% |
| Q4 2025 | 430 | +13% | 111.54% | 11.61 pp | $8.32B | +22% |
| Q3 2025 | 379 | +23% | 123.15% | +6.22 pp | $6.82B | +74% |
| Q2 2025 | 308 | 11% | 116.93% | +2.45 pp | $3.91B | 22% |
| Q1 2025 | 345 | +1.8% | 114.48% | +2.66 pp | $5.05B | 9.5% |
| Q4 2024 | 339 | +2.1% | 111.82% | +0.61 pp | $5.58B | 15% |
| Q3 2024 | 332 | — | 111.21% | — | $6.55B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying CYTK stock.
Based on Q2 2026 13F filings, institutional ownership of Cytokinetics, Incorporated stands at 134.8%, held across 486 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of CYTK, with approximately 20,094,362 shares worth $1.71B as of Q2 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of CYTK, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC, Point72 Asset Management, L.P..
Our composite Smart Money Score for CYTK is 79 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
83 institutions opened new positions in CYTK during Q2 2026, while 48 fully exited. 338 added to existing positions and 51 trimmed.
CYTK institutional ownership rose by 8.96 percentage points quarter-over-quarter, with a net change of +39 holders.
The top 10 institutions account for 47.2% of all reported 13F value in CYTK, and the top 25 account for 65.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Cytokinetics, Incorporated (CYTK) Institutional Ownership