Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in CYTK held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 16.5M | $1.09B | +0.9% | 13.436% | 0.02% |
| 2 | FMR LLC | 10.7M | $706.8M | -16.3% | 8.707% | 0.04% |
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 8.0M | $527.9M | +0.9% | 6.503% | 0.10% |
| 4 | VANGUARD PORTFOLIO MANAGEMENT LLC | 5.8M | $385.2M | — | 4.745% | 0.02% |
| 5 | STATE STREET CORP | 5.7M | $378.7M | -1.4% | 4.665% | 0.01% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 5.5M | $361.8M | — | 4.456% | 0.01% |
| 7 | Avoro Capital Advisors LLC | 3.3M | $219.7M | — | 2.706% | 2.25% |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | 3.2M | $212.0M | +5.2% | 2.611% | 0.01% |
| 9 | BANK OF AMERICA CORP /DE/ | 3.1M | $206.0M | +6.3% | 2.538% | 0.02% |
| 10 | RTW INVESTMENTS, LP | 2.7M | $179.4M | 0.0% | 2.209% | 1.78% |
| 11 | ARMISTICE CAPITAL, LLC | 2.7M | $175.6M | +6.9% | 2.163% | 5.18% |
| 12 | GOLDMAN SACHS GROUP INC | 2.5M | $161.9M | -5.3% | 1.994% | 0.02% |
| 13 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2.2M | $146.5M | -22.9% | 1.805% | 0.02% |
| 14 | UBS Group AG | 2.1M | $138.6M | +85.8% | 1.707% | 0.02% |
| 15 | Caption Management, LLC | 1.9M | $122.4M | — | 1.507% | 1.17% |
| 16 | Polar Capital Holdings Plc | 1.7M | $109.5M | -32.4% | 1.349% | 0.39% |
| 17 | CITADEL ADVISORS LLC | 1.6M | $102.4M | -1.2% | 1.262% | 0.05% |
| 18 | MORGAN STANLEY | 1.5M | $99.2M | +18.9% | 1.222% | 0.01% |
| 19 | Paradigm Biocapital Advisors LP | 1.5M | $97.6M | — | 1.202% | 1.99% |
| 20 | NORTHERN TRUST CORP | 1.4M | $95.0M | +4.4% | 1.171% | 0.01% |
| 21 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.4M | $92.1M | +1.0% | 1.134% | 0.01% |
| 22 | Deep Track Capital, LP | 1.4M | $90.6M | -58.8% | 1.116% | 1.87% |
| 23 | Capital International Investors | 1.3M | $88.2M | +13.6% | 1.087% | 0.02% |
| 24 | Ikarian Capital, LLC | 1.2M | $81.9M | +168.0% | 1.009% | 8.71% |
| 25 | Frazier Life Sciences Management, L.P. | 1.2M | $76.4M | +24.1% | 0.942% | 1.97% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in CYTK — a direct measure of their conviction.
Filings activity in CYTK during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 425 | +1.4% | 98.81% | +4.80 pp | $8.54B | +5.1% |
| Q4 2025 | 419 | +15% | 94.01% | +18.92 pp | $8.12B | +25% |
| Q3 2025 | 365 | +19% | 75.09% | +29.83 pp | $6.49B | +66% |
| Q2 2025 | 308 | 11% | 45.26% | 13.13 pp | $3.91B | 22% |
| Q1 2025 | 345 | +1.8% | 58.39% | 6.15 pp | $5.05B | 9.5% |
| Q4 2024 | 339 | +2.1% | 64.54% | 11.22 pp | $5.58B | 15% |
| Q3 2024 | 332 | 1.5% | 75.76% | 1.34 pp | $6.55B | 1.7% |
| Q2 2024 | 337 | — | 77.10% | — | $6.66B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying CYTK stock.
Based on Q1 2026 13F filings, institutional ownership of Cytokinetics, Incorporated stands at 98.8%, held across 425 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of CYTK, with approximately 16,548,011 shares worth $1.09B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of CYTK, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC.
Our composite Smart Money Score for CYTK is 66 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
84 institutions opened new positions in CYTK during Q1 2026, while 78 fully exited. 240 added to existing positions and 98 trimmed.
CYTK institutional ownership rose by 4.80 percentage points quarter-over-quarter, with a net change of +6 holders.
The top 10 institutions account for 50.0% of all reported 13F value in CYTK, and the top 25 account for 69.6%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Cytokinetics, Incorporated (CYTK) Institutional Ownership