Exelixis, Inc. (EXEL) P/E Ratio History
Historical price-to-earnings valuation from 2011 to 2026
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EXEL Valuation Context
How does the current P/E compare to historical and market benchmarks?
P/E Ratio Analysis
As of May 7, 2026, Exelixis, Inc. (EXEL) trades at a price-to-earnings ratio of 17.5x, with a stock price of $48.70 and trailing twelve-month earnings per share of $3.12.
The current P/E is 41% below its 5-year average of 29.8x. Over the past five years, EXEL's P/E has ranged from a low of 14.5x to a high of 78.0x, placing the current valuation at the 30th percentile of its historical range.
Compared to the Healthcare sector median P/E of 22.1x, EXEL trades at a 21% discount to its sector peers. The sector includes 242 companies with P/E ratios ranging from 0.0x to 178.0x.
The PEG ratio of 0.34 (P/E divided by 58% EPS growth) suggests the stock may be undervalued relative to its earnings growth. Peter Lynch popularized the rule that a PEG below 1.0 indicates an attractive entry point.
Relative to the broader market, EXEL trades at a notable discount to the S&P 500 median P/E of 25.2x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our EXEL DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
EXEL P/E vs Peers
P/E ratio compared to closely matched public peers
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $20B | 15.6 | - | +4173%Best | |
| $6B | 24.7 | - | -34% | |
| $8B | 25.9 | 1.13 | -25% | |
| $4B | 9.4Lowest | - | +68% | |
| $280B | 15.6 | 0.73Best | +8% | |
| $115B | 16.4 | - | +178% | |
| $7B | 146.2 | - | +287% |
Peers sorted by market capitalization. P/E below peers may indicate undervaluation or lower growth expectations. Consider PEG ratio for growth-adjusted comparison.
EXEL Historical P/E Data (2011–2026)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Date | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2026 Q1 | Fri Apr 03 2026 00:00:00 GM | $43.88 | $3.02 | 14.5x | -59% |
| FY2025 Q4 | Fri Jan 02 2026 00:00:00 GM | $43.58 | $2.78 | 15.7x | -56% |
| FY2025 Q3 | Fri Oct 03 2025 00:00:00 GM | $40.09 | $2.37 | 16.9x | -53% |
| FY2025 Q2 | Fri Jul 04 2025 00:00:00 GM | $46.15 | $2.07 | 22.3x | -38% |
| FY2025 Q1 | Fri Apr 04 2025 00:00:00 GM | $34.57 | $2.19 | 15.8x | -56% |
| FY2024 Q4 | $33.30 | $1.76 | 18.9x | -47% | |
| FY2024 Q3 | Fri Sep 27 2024 00:00:00 GM | $25.96 | $1.56 | 16.6x | -54% |
| FY2024 Q2 | Fri Jun 28 2024 00:00:00 GM | $22.47 | $1.16 | 19.3x | -46% |
| FY2024 Q1 | Fri Mar 29 2024 00:00:00 GM | $23.73 | $0.64 | 36.9x | +3% |
| FY2023 Q4 | Sun Dec 31 2023 00:00:00 GM | $23.99 | $0.64 | 37.3x | +4% |
| FY2023 Q3 | Fri Sep 29 2023 00:00:00 GM | $21.85 | $0.28 | 78.0x | +118% |
| FY2023 Q2 | Fri Jun 30 2023 00:00:00 GM | $19.11 | $0.51 | 37.7x | +5% |
Average P/E for displayed period: 35.8x
Full EXEL Stock Analysis
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Start ComparisonEXEL — Frequently Asked Questions
Quick answers to the most common questions about buying EXEL stock.
Is EXEL stock overvalued or undervalued?
EXEL trades at 17.5x P/E, below its 5-year average of 29.8x. At the 30th percentile of historical range, the stock is priced at a discount to its own history.
How does EXEL's valuation compare to peers?
Exelixis, Inc. P/E of 17.5x compares to sector median of 22.1x. The discount suggests lower growth expectations or higher risk.
What is EXEL's PEG ratio?
EXEL PEG ratio is 0.34. Below 1.0 indicates valuation is supported by earnings growth rate. Historical P/E data spans 2011-2026.