Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in FULC held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | SUVRETTA CAPITAL MANAGEMENT, LLC | 6.6M | $50.3M | 0.0% | 12.125% | 1.36% |
| 2 | RA CAPITAL MANAGEMENT, L.P. | 6.1M | $46.4M | 0.0% | 11.188% | 0.49% |
| 3 | BlackRock, Inc. | 5.4M | $41.3M | +26.4% | 9.962% | 0.00% |
| 4 | TCG Crossover Management, LLC | 5.3M | $40.3M | 0.0% | 9.702% | 1.15% |
| 5 | BRAIDWELL LP | 3.1M | $24.0M | +2.4% | 5.793% | 0.80% |
| 6 | Nantahala Capital Management, LLC | 3.1M | $23.4M | -29.0% | 5.637% | 1.20% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 2.7M | $20.7M | — | 4.977% | 0.00% |
| 8 | Siren, L.L.C. | 2.4M | $18.0M | +20.5% | 4.343% | 0.50% |
| 9 | First Turn Management, LLC | 2.3M | $17.3M | +19.2% | 4.169% | 1.93% |
| 10 | abrdn plc | 2.2M | $17.0M | +76.4% | 4.088% | 0.03% |
| 11 | Point72 Asset Management, L.P. | 2.1M | $15.9M | -13.5% | 3.834% | 0.02% |
| 12 | GSK plc | 1.8M | $13.7M | 0.0% | 3.300% | 2.29% |
| 13 | Jones Hill Capital LP | 1.8M | $13.6M | — | 3.275% | 2.91% |
| 14 | D. E. Shaw & Co., Inc. | 1.6M | $12.5M | -15.2% | 3.000% | 0.01% |
| 15 | STATE STREET CORP | 1.5M | $11.9M | +54.2% | 2.864% | 0.00% |
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 1.5M | $11.4M | +34.4% | 2.747% | 0.00% |
| 17 | CITADEL ADVISORS LLC | 1.4M | $10.4M | +3.6% | 2.496% | 0.00% |
| 18 | Alyeska Investment Group, L.P. | 1.3M | $10.2M | — | 2.455% | 0.03% |
| 19 | Assenagon Asset Management S.A. | 1.2M | $9.2M | — | 2.206% | 0.01% |
| 20 | DIMENSIONAL FUND ADVISORS LP | 1.1M | $8.7M | +7.5% | 2.089% | 0.00% |
| 21 | Vestal Point Capital, LP | 1.1M | $8.4M | +15.8% | 2.033% | 0.24% |
| 22 | Ikarian Capital, LLC | 1.0M | $8.0M | -23.7% | 1.939% | 0.86% |
| 23 | Qube Research & Technologies Ltd | 975K | $7.5M | +148.3% | 1.801% | 0.01% |
| 24 | Connor, Clark & Lunn Investment Management Ltd. | 737K | $5.7M | +26.5% | 1.361% | 0.01% |
| 25 | VANGUARD PORTFOLIO MANAGEMENT LLC | 599K | $4.6M | — | 1.108% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in FULC — a direct measure of their conviction.
Filings activity in FULC during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 162 | 4.1% | 199.99% | +0.00 pp | $526M | 30% |
| Q4 2025 | 169 | +34% | 199.99% | +0.00 pp | $753M | +55% |
| Q3 2025 | 126 | +4.1% | 199.99% | +2.10 pp | $485M | +31% |
| Q2 2025 | 121 | +3.4% | 197.89% | +120.71 pp | $369M | +156% |
| Q1 2025 | 117 | 1.7% | 77.18% | 51.07 pp | $144M | 40% |
| Q4 2024 | 119 | 4.8% | 128.25% | +26.79 pp | $239M | +26% |
| Q3 2024 | 125 | +4.2% | 101.46% | 98.53 pp | $189M | 51% |
| Q2 2024 | 120 | — | 199.99% | — | $384M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying FULC stock.
Based on Q1 2026 13F filings, institutional ownership of Fulcrum Therapeutics, Inc. stands at 200.0%, held across 162 reporting institutions.
SUVRETTA CAPITAL MANAGEMENT, LLC is the largest reported institutional holder of FULC, with approximately 6,561,111 shares worth $0.05B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of FULC, including Point72 Asset Management, L.P., CITADEL ADVISORS LLC.
Our composite Smart Money Score for FULC is 50 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
36 institutions opened new positions in FULC during Q1 2026, while 43 fully exited. 30 added to existing positions and 96 trimmed.
FULC institutional ownership rose by 0.00 percentage points quarter-over-quarter, with a net change of -7 holders.
The top 10 institutions account for 56.8% of all reported 13F value in FULC, and the top 25 account for 85.6%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Fulcrum Therapeutics, Inc. (FULC) Institutional Ownership