Free cash flow burn deepened to -$81.2M in 2026Q2 (FCF margin -181.6%), with operating cash flow covering only 0.73x net losses, and no capital returns as all cash is directed to operations.
GRAIL Inc. (GRAL) cash flow statement — 8-year operating, investing & financing cash flows
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 |
|---|
| Cash from Operations | -294.75M | -299.01M | -577.16M | -595.8M | -561.31M | -688.13M | -232M | -245.79M | -209.26M |
| Operating CF Margin % | - | -203.17% | -459.54% | -639.92% | -1010.46% | -4709.35% | - | - | - |
| Operating CF Growth % | 74.85% | 48.19% | 3.13% | -6.14% | 18.43% | -196.61% | 5.61% | -17.46% | - |
| Net Income | -391.59M | -408.35M | -2.03B | -1.47B | -5.4B | -1.25B | -312.16M | -244.85M | -275.72M |
| Depreciation & Amortization | -972K | 156.34M | 158.06M | 158.7M | 154.76M | 58.45M | 7.56M | 10.31M | 14.08M |
| Stock-Based Compensation | 5.97M | 58.28M | 86.08M | 97.23M | 75.73M | 681.91M | 45.99M | 28.39M | 11.04M |
| Deferred Taxes | -12.15M | -126.15M | -134.25M | -38.15M | -39.06M | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 104.67M | 8.46M | 1.36B | 644.38M | 4.66B | -201M | 9.38M | -353K | 1.66M |
| Working Capital Changes | -677K | 12.41M | -24.28M | 7.72M | -14.46M | 21.59M | 17.22M | -39.28M | 39.67M |
| Change in Receivables | -5.68M | 1.69M | -3.37M | -1.38M | -8.68M | -6.88M | 0 | 0 | 0 |
| Change in Inventory | -844K | 2.62M | 3.07M | -1.94M | -14.08M | -5.67M | 0 | 0 | 0 |
| Change in Payables | 3.79M | -2.73M | -14.63M | 2.89M | 2.34M | 1.3M | 0 | -6.55M | -338K |
| Cash from Investing | -310.04M | -85.05M | -551.01M | -12.89M | -22.86M | 344.81M | -12.79M | 133.04M | -93.39M |
| Capital Expenditures | -504K | -909K | -5.21M | -12.89M | -22.86M | -69.93M | -11.9M | -3.33M | -15.99M |
| CapEx % of Revenue | 0.3% | 0.62% | 4.15% | 13.84% | 41.15% | 478.55% | - | - | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | -85.05M | 0 | 0 | 0 | 0 | 414.74M | -885K | 136.37M | -77.4M |
| Cash from Financing | 536.93M | 423.32M | 1.24B | 463.77M | 604.82M | 394.74M | 275.11M | 160.33M | 300.62M |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | -812K | -1.56M | -1.51M |
| Equity Issued (Net) | 113.61M | 423.32M | 0 | 0 | 0 | 5.81M | 0 | 0 | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | -170K | 0 | 0 | 0 |
| Other Financing | 423.32M | 0 | 1.24B | 463.77M | 604.82M | 388.93M | 275.92M | 161.88M | 302.13M |
| Net Change in Cash | -68.16M | 39.12M | 116.07M | -144.62M | 20.13M | -143.19M | 30.35M | 47.69M | -1.55M |
| Free Cash Flow | -295.25M | -299.01M | -582.36M | -608.69M | -584.17M | -758.06M | -243.91M | -249.13M | -225.25M |
| FCF Margin % | -178.66% | -203.17% | -463.68% | -653.76% | -1051.61% | -5187.9% | - | - | - |
| FCF Growth % | 20.58% | 48.66% | 4.32% | -4.2% | 22.94% | -210.8% | 2.09% | -10.6% | - |
| FCF per Share | -6.85 | -8.14 | -18.26 | -19.60 | -18.81 | -24.41 | -1.97 | -2.02 | -1.97 |
| FCF Conversion (FCF/Net Income) | 0.75x | 0.73x | 0.28x | 0.41x | 0.10x | 0.55x | 0.74x | 1.00x | 0.76x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying GRAL stock.
GRAIL Inc. (GRAL) generated $-299.0M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
GRAIL Inc. (GRAL) reported negative free cash flow of $299.0M in 2025, indicating capital requirements exceeded cash from operations.
GRAIL Inc. (GRAL) spent $0.9M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
Key Metrics
Top Statement Risk
Reimbursement and cash burn
Metrics are mathematically derived from official filings.
Cash Conversion Lags Reported Losses
Operating cash flow averaged 0.73x net loss over the last four quarters, per SEC filings, indicating non-cash charges like D&A and SBC partially offset cash burn, but the gap remains wide.
The OCF/NI ratio has hovered between 0.64 and 0.93 in recent quarters, meaning cash outflows are consistently less than accounting losses. This suggests that while the company is burning cash, the reported net loss overstates the immediate cash drain due to significant non-cash items. However, the persistent negative OCF indicates that the business is still far from self-funding, and the quality of earnings is low as losses are driven by operational spending rather than one-time charges.
Free Cash Flow Burn Deepens with Scale
FCF margin worsened to -181.6% in 2026Q2 from -144.4% in 2025Q4, per financial statements, as revenue growth has not yet translated into cash generation, with quarterly FCF averaging -$80M.
Despite accelerating revenue growth, FCF has remained deeply negative, with the most recent quarter showing a burn of $81.2M. The FCF margin has deteriorated from -2.1% in 2026Q1 to -181.6% in 2026Q2, indicating that the cost structure is not leveraging with scale. This suggests that the company is still in a heavy investment phase, and investors should monitor whether the increasing revenue can eventually outpace the fixed cost base.
Minimal CapEx Signals Asset-Light Model
CapEx averaged just 1.0% of revenue in 2026Q2, per reported data, indicating a laboratory-based model with low capital intensity, but this may understate the need for future investment in sequencing capacity.
Capital expenditures have been consistently below $1M per quarter, which is remarkably low for a diagnostics company. This suggests that the company's growth is not currently constrained by physical capacity, but rather by clinical validation and market adoption. However, the negative gross margins imply that the cost of goods sold is high, likely due to consumables and labor, which may require future CapEx to achieve economies of scale. The low CapEx/Revenue ratio may also indicate that the company is outsourcing manufacturing or using leased facilities, which could shift costs to operating expenses.
Working Capital Swings Reflect Payment Timing
Working capital changes have been volatile, ranging from -$16.3M to +$10.9M over the past year, per cash flow data, suggesting that cash collections from tests are unpredictable and may lag test volumes.
The working capital adjustments are relatively small compared to the overall cash burn, but they show significant quarter-to-quarter variability. This could be due to the timing of payments from self-pay patients or institutional contracts, which may not follow a consistent pattern. The positive working capital in some quarters (e.g., +$8.2M in 2026Q2) suggests that the company is collecting on receivables, but the negative swings indicate that payables or inventory management may be causing cash outflows. Investors should monitor whether the company can stabilize its working capital cycle as revenue scales.
No Capital Returns, All Cash to Operations
No dividends or buybacks were paid in any quarter, per cash flow statements, with all available cash directed toward funding operations and clinical trials, reflecting a pure reinvestment strategy.
The company has not returned any capital to shareholders, which is typical for a pre-profit biotech. The absence of dividends and buybacks indicates that management is prioritizing investment in the business, particularly in R&D and commercial expansion. However, this also means that shareholders are entirely reliant on future value creation from the Galleri test and other pipeline assets. The lack of capital returns, combined with the persistent cash burn, underscores the need for external financing or a significant inflection in profitability.
Cumulative Losses Outpace Cash Burn
Over the last ten quarters, cumulative net losses totaled -$2.5B while operating cash flow was -$1.0B, per reported data, indicating that non-cash charges, including the spin-off, account for a large portion of the accounting losses.
The cumulative gap between net income and operating cash flow is substantial, driven largely by the one-time spin-off charges in 2024Q2 and ongoing non-cash expenses like D&A and SBC. This divergence suggests that the company's cash burn is less severe than the income statement implies, but the underlying trend is still negative. Investors should focus on the operating cash flow trend, which has remained consistently negative, indicating that the business is not yet generating cash from its operations. The spin-off distortion is a one-time event, but the ongoing gap highlights the need for careful cash flow analysis.
What the Cash Flow Statement Obscures
Stock-based compensation of $19.6M in 2026Q2, per cash flow data, is a non-cash expense that reduces reported losses but dilutes shareholders, while the spin-off's one-time charges distort historical comparisons.
The cash flow statement reveals that SBC is a significant recurring expense, totaling over $100M annually, which is not reflected in operating cash flow but does impact the income statement. This suggests that the true economic cost to shareholders is higher than the cash burn alone indicates. Additionally, the 2024Q2 spin-off from Illumina included massive one-time charges that skew the cumulative net income versus operating cash flow gap, making historical trends less comparable. Investors should adjust for these items to assess the underlying cash generation capability of the core business.