GRAIL, Inc. (GRAL) Financial Ratios
8 years of historical data (2018–2025) · Healthcare · Medical - Diagnostics & Research
EV/EBITDA
N/A
—
5yr avg: N/A
P/FCF
N/A
—
5yr avg: N/A
P/B Ratio
↑
0.89
↑+24% vs avg
5yr avg: 0.72
30Y Low0.2·High1.2
ROE
↑
-16.1%
↓+63% vs avg
5yr avg: -43.8%
30Y Low-77%·High-16%
Debt/EBITDA
N/A
—
5yr avg: N/A
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
GRAL Valuation Multiples
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
GRAIL, Inc. currently has a negative P/E ratio, indicating the company is operating at a loss on a trailing-twelve-month basis.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $2.6B | $3.1B | $569M | — | — | — | — | — | — |
| Enterprise Value | $2.4B | $3.0B | $423M | — | — | — | — | — | — |
| P/E Ratio → | -5.65 | — | — | — | — | — | — | — | — |
| P/S Ratio | 17.49 | 21.37 | 4.53 | — | — | — | — | — | — |
| P/B Ratio | 0.89 | 1.22 | 0.23 | — | — | — | — | — | — |
| P/FCF | — | — | — | — | — | — | — | — | — |
| P/OCF | — | — | — | — | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
GRAL EV Ratios
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 20.34 | 3.37 | — | — | — | — | — | — |
| EV / EBITDA | — | — | — | — | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | — | — | — | — |
GRAL Profitability
Margins and return-on-capital ratios measuring operating efficiency
GRAIL, Inc. earns an operating margin of -363.0%. Operating margins have expanded from -1627.6% to -363.0% over the past 3 years, signaling improving operational efficiency. A negative ROE of -16.1% indicates the company is currently destroying shareholder equity.
Margins
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | -42.5% | -42.5% | -62.1% | -102.7% | -209.6% | -684.4% | — | — | — |
| Operating Margin | -363.0% | -363.0% | -1743.0% | -1627.6% | -9798.2% | -8659.6% | — | — | — |
| Net Profit Margin | -277.5% | -277.5% | -1613.9% | -1574.2% | -9719.3% | -8539.4% | — | — | — |
Return on Capital
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|---|
| ROE | -16.1% | -16.1% | -65.9% | -35.4% | -76.7% | -25.0% | -56.1% | -42.6% | -45.9% |
| ROA | -13.8% | -13.8% | -53.8% | -28.9% | -70.4% | -23.9% | -46.5% | -37.0% | -40.1% |
| ROIC | -16.8% | -16.8% | -54.8% | -27.9% | -59.1% | -19.4% | -52.5% | -40.1% | -42.5% |
| ROCE | -18.6% | -18.6% | -60.0% | -30.7% | -72.1% | -24.7% | -52.2% | -42.5% | -46.9% |
GRAL Leverage & Debt
Solvency and debt-coverage ratios — lower is generally safer
The company holds a net cash position — cash of $250M exceeds total debt of $98M, providing substantial financial flexibility for buybacks, acquisitions, or weathering downturns.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.04 | 0.04 | 0.03 | 0.02 | 0.02 | 0.01 | 0.11 | 0.08 | 0.00 |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | -0.06 | -0.06 | -0.00 | -0.03 | -0.01 | -0.19 | -0.18 | -0.15 |
| Net Debt / EBITDA | — | — | — | — | — | — | — | — | — |
| Debt / FCF | — | — | — | — | — | — | — | — | — |
| Interest Coverage | — | — | — | — | — | — | — | — | — |
Net cash position: cash ($250M) exceeds total debt ($98M)
GRAL Liquidity & Efficiency
Short-term solvency ratios and asset-utilisation metrics
GRAIL, Inc.'s current ratio of 11.97x is well above the 1.0 safety threshold, indicating strong short-term liquidity with ample room to cover current liabilities. The current ratio has improved from 0.95x to 11.97x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 11.97 | 11.97 | 10.66 | 0.95 | 2.19 | 2.48 | 7.10 | 12.41 | 8.75 |
| Quick Ratio | 11.77 | 11.77 | 10.42 | 0.82 | 2.04 | 2.48 | 7.10 | 12.41 | 8.75 |
| Cash Ratio | 11.35 | 11.35 | 9.92 | 0.59 | 1.79 | 2.26 | 6.95 | 12.12 | 8.65 |
| Asset Turnover | — | 0.05 | 0.04 | 0.02 | 0.01 | 0.00 | — | — | — |
| Inventory Turnover | 13.10 | 13.10 | 10.93 | 8.70 | 8.71 | — | — | — | — |
| Days Sales Outstanding | — | 45.37 | 71.61 | 87.63 | 122.31 | 171.91 | — | — | — |
GRAL Shareholder Yields
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
GRAIL, Inc. does not currently pay a dividend and has no material buyback yield, reinvesting earnings back into the business.
Dividends
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — |
Total Shareholder Return Metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | — | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | — | — | — | — | — | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | — | — | — | — | — | — |
| Shares Outstanding | — | $37M | $32M | $31M | $31M | $31M | $124M | $123M | $114M |
Peer Comparison
Compare GRAL with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
 GRALYou | $3B | -5.6 | — | — | -42.5% | -363.0% | -16.1% | -16.8% | — |
 EXAS | $20B | -95.4 | — | 56.1 | 69.7% | -6.4% | -8.7% | -3.6% | — |
 ILMN | $22B | 26.2 | 20.1 | 23.3 | 66.7% | 19.9% | 33.4% | 16.8% | 2.3 |
 GH | $12B | -27.8 | — | — | 64.5% | -44.5% | — | -35.0% | — |
 NTRA | $30B | -140.6 | — | 427.2 | 60.3% | -13.1% | -19.4% | -33.3% | — |
 FDMT | $600M | -4.3 | — | — | 91.1% | -187.2% | -27.6% | -28.1% | — |
 ACMR | $4B | 40.4 | 25.5 | — | 44.4% | 12.1% | 6.2% | 7.0% | 2.4 |
 CDNA | $1B | -52.4 | — | 29.9 | 67.0% | -5.5% | -6.3% | -5.7% | — |
 PACB | $516M | -1.6 | — | — | 24.2% | -308.0% | -51.3% | -27.6% | — |
 SEER | $105M | -1.4 | — | — | 49.0% | -717.7% | -23.9% | -21.3% | — |
 TMO | $176B | 26.7 | 19.0 | 27.9 | 37.7% | 18.2% | 13.1% | 7.5% | 3.8 |
| Healthcare Median | — | 22.1 | 14.1 | 18.7 | 63.9% | -5.3% | -33.7% | -10.8% | 3.3 |
Peer selection based on competitive and market overlap. Compare multiple stocks →
Download Financial Ratios Data
Includes 30+ ratios · 8 years · Updated daily
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Start ComparisonGRAL — Frequently Asked Questions
Quick answers to the most common questions about buying GRAL stock.
What is GRAIL, Inc.'s P/E ratio?
GRAIL, Inc.'s current P/E ratio is -5.6x. This places it at the 50th percentile of its historical range.
What is GRAIL, Inc.'s ROE?
GRAIL, Inc.'s return on equity (ROE) is -16.1%. The historical average is -45.5%.
Is GRAL stock overvalued?
Based on historical data, GRAIL, Inc. is trading at a P/E of -5.6x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
What are GRAIL, Inc.'s profit margins?
GRAIL, Inc. has -42.5% gross margin and -363.0% operating margin.