Krystal Biotech, Inc. (KRYS) Revenue History
Annual and quarterly revenue from 2016 to present
KRYS Revenue Over Time (2016–2025)
KRYS Revenue Growth History
2 of 3 years with positive growth- FY2016 revenue growth
- N/A
- FY2017 revenue growth
- N/A
- FY2018 revenue growth
- N/A
- FY2019 revenue growth
- -100.0%
- FY2020 revenue growth
- N/A
- FY2021 revenue growth
- N/A
- FY2022 revenue growth
- N/A
- FY2023 revenue growth
- N/A
- FY2024 revenue growth
- +473.0%
- FY2025 revenue growth
- +33.9%
| Quarter | Revenue | YoY |
|---|---|---|
| Q1 2026 | $116.4M | +31.9% |
| Q4 2025 | $107.1M | +17.5% |
| Q3 2025 | $97.8M | +16.6% |
| Q2 2025 | $96.0M | +36.6% |
| Q1 2025 | $88.2M | +94.9% |
| Q4 2024 | $91.1M | +116.3% |
| Q3 2024 | $83.8M | +879.9% |
| Q2 2024 | $70.3M | — |
Multi-year avg. share of annual revenue by fiscal quarter
KRYS Revenue Analysis (2016–2025)
Current Revenue & Growth
As of June 22, 2026, Krystal Biotech, Inc. (KRYS) generated trailing twelve-month (TTM) revenue of $417.3 million, reflecting explosive growth of +31.9% year-over-year. The most recent quarter (Q1 2026) recorded $116.4 million in revenue, up 8.6% sequentially.
Historical Growth Trajectory
KRYS's historical revenue data shows various trends over time. Krystal Biotech, Inc.'s highest annual revenue of $389.1 million was recorded in 2025, an all-time high.
Peer Comparison
Compared to Healthcare sector peers — including RARE (+13.3% YoY), FOLD (+20.0% YoY), and ACAD (+9.9% YoY) — KRYS has outperformed the peer group in revenue growth. Compare KRYS vs RARE →
KRYS Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| KRYSCurrent | $417M | +31.9% | - | 41.5% | |
 RARE | $673M | +13.3% | +19.9% | -79.5% | |
 FOLD | $634M | +20.0% | +19.4% | 5.4% | |
 ACAD | $1.1B | +9.9% | +19.4% | 9.8% | |
 PTCT | $1.7B | -53.3% | +35.4% | 49.5% |
KRYS Historical Revenue Data (2016–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $389.1M | +33.9% | $360.4M | 92.6% | $161.3M | 41.5% |
| 2024 | $290.5M | +473.0% | $270.5M | 93.1% | $65.7M | 22.6% |
| 2023 | $50.7M | - | $47.6M | 93.9% | $-109,727,000 | -216.4% |
| 2022 | $0 | - | $0 | - | $-145,196,000 | - |
| 2021 | $0 | - | $0 | - | $-68,275,000 | - |
| 2020 | $0 | - | $-1,851,000 | - | $-32,999,000 | - |
| 2019 | $0 | -100.0% | $-974,000 | - | $-22,081,000 | - |
| 2018 | $1.0M | - | $886K | 86.3% | $-11,916,000 | -1160.3% |
| 2017 | $0 | - | $-23,000 | - | $-4,772,000 | - |
| 2016 | $0 | - | $-2,000 | - | $-1,143,000 | - |
Full Stock Analysis
Deep dive into KRYS consensus models and risk factors.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10+ years return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
KRYS — Frequently Asked Questions
Quick answers to the most common questions about buying KRYS stock.
Is KRYS's revenue growth accelerating or slowing?
KRYS revenue growth is accelerating. TTM revenue reached $417M, up +31.9% year-over-year — ahead of the 5-year CAGR of N/A. This indicates the business is expanding faster than its historical baseline.
What is KRYS's revenue history from 2016 to 2026?
Krystal Biotech, Inc. (KRYS) revenue history spans 2016 to 2026. TTM revenue as of 2026 is $417M, growing at +31.9% YoY. The 5-year CAGR is N/A. Complete annual and quarterly revenue figures are available on this page, including gross profit, operating income, and margin trends.
What is KRYS's long-term revenue growth rate (CAGR)?
Krystal Biotech, Inc.'s 5-year revenue CAGR of N/A reflects the sustained nature of its business expansion. As of 2026, the current YoY growth rate of +31.9% is above this long-term average. CAGR is the most reliable measure of sustained revenue momentum for KRYS.
Why does KRYS's quarterly revenue fluctuate?
KRYS quarterly revenue can fluctuate significantly between periods. A quarter-over-quarter (QoQ) change does not always indicate a trend; comparing the same quarter year-over-year (YoY) is a more reliable signal for underlying growth. Krystal Biotech, Inc.'s revenue data from 2016 to 2026 shows full historical quarterly detail on this page.
How is KRYS's revenue distributed by segment?
KRYS reports revenue broken down by product line and geographic region. The segment breakdown on this page shows which business units contribute the most to total revenue as of the latest fiscal year. Concentration in a single segment above 50% indicates category dependence, while a diversified mix signals more resilient revenue streams.
How does KRYS's revenue compare to industry peers?
Krystal Biotech, Inc. (KRYS) with TTM revenue of $417M and +31.9% YoY growth can be benchmarked against sector peers using the comparison table on this page. Revenue growth relative to peers indicates market share gains or losses. The peer section shows TTM revenue, YoY growth, and operating margin for direct comparisons.