Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in MIRM held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Frazier Life Sciences Management, L.P. | 7.7M | $709.4M | +13.0% | 15.299% | 18.25% |
| 2 | JANUS HENDERSON GROUP PLC | 6.8M | $627.3M | +11.9% | 13.525% | 0.31% |
| 3 | BlackRock, Inc. | 3.8M | $355.3M | +5.5% | 7.663% | 0.01% |
| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 2.4M | $223.1M | β | 4.810% | 0.01% |
| 5 | FMR LLC | 2.0M | $181.6M | +204.0% | 3.915% | 0.01% |
| 6 | STATE STREET CORP | 1.9M | $179.6M | -9.3% | 3.873% | 0.01% |
| 7 | BVF INC/IL | 1.6M | $146.4M | +6.0% | 3.157% | 4.66% |
| 8 | VANGUARD PORTFOLIO MANAGEMENT LLC | 1.4M | $132.3M | β | 2.853% | 0.01% |
| 9 | EVENTIDE ASSET MANAGEMENT, LLC | 1.4M | $130.1M | -32.7% | 2.807% | 2.15% |
| 10 | WELLINGTON MANAGEMENT GROUP LLP | 1.3M | $123.3M | +7.8% | 2.659% | 0.02% |
| 11 | Novo Holdings A/S | 1.3M | $122.4M | +4.8% | 2.639% | 9.92% |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 1.3M | $116.4M | +18.5% | 2.510% | 0.01% |
| 13 | TANG CAPITAL MANAGEMENT LLC | 1.2M | $114.2M | 0.0% | 2.462% | 5.80% |
| 14 | CITADEL ADVISORS LLC | 1.1M | $98.3M | +24.7% | 2.119% | 0.05% |
| 15 | TCG Crossover Management, LLC | 1.1M | $98.1M | +1611.6% | 2.116% | 2.81% |
| 16 | BNP PARIBAS ARBITRAGE, SA | 911K | $84.2M | +39.0% | 1.816% | 0.04% |
| 17 | Rock Springs Capital Management LP | 811K | $74.9M | +6.4% | 1.616% | 4.42% |
| 18 | TWO SIGMA INVESTMENTS, LP | 775K | $71.6M | +99.4% | 1.544% | 0.06% |
| 19 | Capital World Investors | 724K | $66.9M | β | 1.443% | 0.01% |
| 20 | BANK OF AMERICA CORP /DE/ | 722K | $66.7M | +1.2% | 1.439% | 0.00% |
| 21 | FRANKLIN RESOURCES INC | 715K | $66.0M | +9.8% | 1.424% | 0.02% |
| 22 | Clearbridge Investments, LLC | 672K | $62.1M | -22.4% | 1.338% | 0.05% |
| 23 | GOLDMAN SACHS GROUP INC | 662K | $61.2M | -8.6% | 1.319% | 0.01% |
| 24 | Paradigm Biocapital Advisors LP | 625K | $57.7M | β | 1.245% | 1.18% |
| 25 | Bank of New York Mellon Corp | 585K | $54.0M | +3.4% | 1.164% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in MIRM β a direct measure of their conviction.
Filings activity in MIRM during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 304 | +8.6% | 120.62% | +28.40 pp | $6.02B | +31% |
| Q4 2025 | 280 | +4.9% | 92.22% | +11.26 pp | $4.60B | +14% |
| Q3 2025 | 267 | +24% | 80.96% | +27.34 pp | $4.04B | +51% |
| Q2 2025 | 215 | +1.9% | 53.62% | +9.21 pp | $2.67B | +21% |
| Q1 2025 | 211 | +4.5% | 44.41% | +4.66 pp | $2.21B | +12% |
| Q4 2024 | 202 | +15% | 39.75% | +1.84 pp | $1.98B | +4.9% |
| Q3 2024 | 176 | +12% | 37.91% | +3.75 pp | $1.89B | +11% |
| Q2 2024 | 157 | β | 34.16% | β | $1.70B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying MIRM stock.
Based on Q1 2026 13F filings, institutional ownership of Mirum Pharmaceuticals, Inc. stands at 120.6%, held across 304 reporting institutions.
Frazier Life Sciences Management, L.P. is the largest reported institutional holder of MIRM, with approximately 7,679,684 shares worth $0.71B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of MIRM, including CITADEL ADVISORS LLC, TWO SIGMA INVESTMENTS, LP.
Our composite Smart Money Score for MIRM is 68 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
68 institutions opened new positions in MIRM during Q1 2026, while 44 fully exited. 189 added to existing positions and 45 trimmed.
MIRM institutional ownership rose by 28.40 percentage points quarter-over-quarter, with a net change of +24 holders.
The top 10 institutions account for 46.7% of all reported 13F value in MIRM, and the top 25 account for 66.9%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.