Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in MIRM held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Frazier Life Sciences Management, L.P. | 7.7M | $899.1M | 0.0% | 12.593% | 19.58% |
| 2 | Jupiter Topco LLC | 5.9M | $691.7M | — | 9.690% | 0.28% |
| 3 | BlackRock, Inc. | 4.4M | $513.9M | +14.1% | 7.199% | 0.01% |
| 4 | FMR LLC | 3.7M | $429.7M | +86.8% | 6.019% | 0.02% |
| 5 | VANGUARD PORTFOLIO MANAGEMENT LLC | 2.4M | $278.3M | +66.0% | 3.898% | 0.01% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 2.3M | $263.9M | -6.7% | 3.696% | 0.01% |
| 7 | STATE STREET CORP | 2.2M | $254.1M | +11.6% | 3.560% | 0.00% |
| 8 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1.4M | $164.5M | +318.5% | 2.304% | 0.49% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 1.4M | $163.2M | +10.6% | 2.286% | 0.01% |
| 10 | Invesco Ltd. | 1.4M | $159.7M | +378.2% | 2.237% | 0.01% |
| 11 | WELLINGTON MANAGEMENT GROUP LLP | 1.3M | $153.4M | -1.9% | 2.148% | 0.03% |
| 12 | EVENTIDE ASSET MANAGEMENT, LLC | 1.2M | $146.2M | -11.4% | 2.047% | 1.95% |
| 13 | TANG CAPITAL MANAGEMENT LLC | 1.2M | $144.7M | 0.0% | 2.027% | 6.57% |
| 14 | Capital World Investors | 1.2M | $135.0M | +59.2% | 1.892% | 0.02% |
| 15 | FRANKLIN RESOURCES INC | 1.2M | $135.0M | +61.3% | 1.890% | 0.03% |
| 16 | Novo Holdings A/S | 1.1M | $131.7M | -15.1% | 1.845% | 7.65% |
| 17 | TCG Crossover Management, LLC | 1.1M | $124.3M | 0.0% | 1.742% | 2.99% |
| 18 | BVF INC/IL | 1.1M | $123.6M | -33.4% | 1.732% | 3.16% |
| 19 | Polar Capital Holdings Plc | 846K | $99.0M | +198.3% | 1.387% | 0.23% |
| 20 | Rock Springs Capital Management LP | 798K | $93.4M | -1.6% | 1.309% | 4.56% |
| 21 | NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 752K | $88.0M | +85.5% | 1.233% | 0.13% |
| 22 | AMERIPRISE FINANCIAL INC | 727K | $85.1M | +231.4% | 1.192% | 0.02% |
| 23 | TWO SIGMA INVESTMENTS, LP | 690K | $80.8M | -10.9% | 1.132% | 0.06% |
| 24 | Bank of New York Mellon Corp | 670K | $78.4M | +14.6% | 1.099% | 0.01% |
| 25 | Clearbridge Investments, LLC | 640K | $74.9M | -4.8% | 1.049% | 0.06% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in MIRM — a direct measure of their conviction.
Filings activity in MIRM during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 331 | +5.8% | 117.32% | 1.86 pp | $7.97B | +31% |
| Q1 2026 | 313 | +11% | 119.18% | 5.61 pp | $6.06B | +32% |
| Q4 2025 | 281 | +4.5% | 124.79% | +5.96 pp | $4.60B | +14% |
| Q3 2025 | 269 | +25% | 118.83% | +1.34 pp | $4.04B | +51% |
| Q2 2025 | 215 | +1.9% | 117.49% | +4.99 pp | $2.67B | +21% |
| Q1 2025 | 211 | +4.5% | 112.50% | 0.39 pp | $2.21B | +12% |
| Q4 2024 | 202 | +15% | 112.89% | 1.45 pp | $1.98B | +4.9% |
| Q3 2024 | 176 | — | 114.34% | — | $1.89B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying MIRM stock.
Based on Q2 2026 13F filings, institutional ownership of Mirum Pharmaceuticals, Inc. stands at 117.3%, held across 331 reporting institutions.
Frazier Life Sciences Management, L.P. is the largest reported institutional holder of MIRM, with approximately 7,679,684 shares worth $0.90B as of Q2 2026.
Yes — 1 widely-followed marquee investor appear among the top 25 institutional holders of MIRM, including TWO SIGMA INVESTMENTS, LP.
Our composite Smart Money Score for MIRM is 41 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
57 institutions opened new positions in MIRM during Q2 2026, while 42 fully exited. 222 added to existing positions and 44 trimmed.
MIRM institutional ownership fell by 1.86 percentage points quarter-over-quarter, with a net change of +18 holders.
The top 10 institutions account for 47.9% of all reported 13F value in MIRM, and the top 25 account for 69.2%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Mirum Pharmaceuticals, Inc. (MIRM) Institutional Ownership