Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in MNPR held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | JANUS HENDERSON GROUP PLC | 1.3M | $72.1M | 0.0% | 19.666% | 0.04% |
| 2 | RA CAPITAL MANAGEMENT, L.P. | 667K | $36.6M | 0.0% | 9.960% | 0.39% |
| 3 | Saturn V Capital Management LP | 346K | $18.9M | +6.1% | 5.159% | 3.43% |
| 4 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 324K | $17.7M | +89.8% | 4.833% | 0.21% |
| 5 | BlackRock, Inc. | 317K | $17.3M | +24.2% | 4.726% | 0.00% |
| 6 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 309K | $16.9M | -51.6% | 4.615% | 0.03% |
| 7 | Siren, L.L.C. | 270K | $14.8M | +27.2% | 4.032% | 0.41% |
| 8 | ADAR1 Capital Management, LLC | 264K | $14.5M | +13.0% | 3.945% | 0.90% |
| 9 | Polar Capital Holdings Plc | 227K | $12.4M | +114.2% | 3.381% | 0.04% |
| 10 | VANGUARD CAPITAL MANAGEMENT LLC | 218K | $12.0M | β | 3.261% | 0.00% |
| 11 | WELLINGTON MANAGEMENT GROUP LLP | 174K | $9.6M | -22.9% | 2.603% | 0.00% |
| 12 | Sio Capital Management, LLC | 174K | $9.5M | β | 2.590% | 1.37% |
| 13 | BALYASNY ASSET MANAGEMENT LLC | 136K | $7.5M | +327.6% | 2.037% | 0.03% |
| 14 | TCG Crossover Management, LLC | 132K | $7.2M | -6.9% | 1.972% | 0.21% |
| 15 | Alyeska Investment Group, L.P. | 100K | $5.5M | +150.0% | 1.493% | 0.02% |
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 100K | $5.5M | +0.9% | 1.492% | 0.00% |
| 17 | Vivo Capital, LLC | 91K | $5.0M | 0.0% | 1.351% | 0.41% |
| 18 | STATE STREET CORP | 88K | $4.8M | +5.2% | 1.319% | 0.00% |
| 19 | Bank of New York Mellon Corp | 79K | $4.3M | +21.2% | 1.174% | 0.00% |
| 20 | Vestal Point Capital, LP | 65K | $3.6M | β | 0.976% | 0.10% |
| 21 | Walleye Capital LLC | 63K | $3.5M | β | 0.942% | 0.01% |
| 22 | BANK OF AMERICA CORP /DE/ | 60K | $3.3M | +838.2% | 0.891% | 0.00% |
| 23 | CITADEL ADVISORS LLC | 58K | $3.2M | +1051.9% | 0.872% | 0.00% |
| 24 | MILLENNIUM MANAGEMENT LLC | 53K | $2.9M | -30.9% | 0.790% | 0.00% |
| 25 | VANGUARD PORTFOLIO MANAGEMENT LLC | 46K | $2.5M | β | 0.686% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in MNPR β a direct measure of their conviction.
Filings activity in MNPR during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 80 | +9.6% | 84.61% | 4.86 pp | $339M | 5.4% |
| Q4 2025 | 73 | +33% | 89.47% | +0.99 pp | $358M | +1.1% |
| Q3 2025 | 55 | +25% | 88.48% | +60.27 pp | $354M | +214% |
| Q2 2025 | 44 | +22% | 28.21% | +0.97 pp | $113M | +3.5% |
| Q1 2025 | 36 | +89% | 27.24% | +12.97 pp | $109M | +91% |
| Q4 2024 | 19 | +171% | 14.27% | +14.24 pp | $57M | +53861% |
| Q3 2024 | 7 | 46% | 0.03% | 0.04 pp | $0M | 64% |
| Q2 2024 | 13 | β | 0.07% | β | $0M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying MNPR stock.
Based on Q1 2026 13F filings, institutional ownership of Monopar Therapeutics Inc. stands at 84.6%, held across 80 reporting institutions.
JANUS HENDERSON GROUP PLC is the largest reported institutional holder of MNPR, with approximately 1,317,410 shares worth $0.07B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of MNPR, including CITADEL ADVISORS LLC, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for MNPR is 48 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
20 institutions opened new positions in MNPR during Q1 2026, while 13 fully exited. 21 added to existing positions and 38 trimmed.
MNPR institutional ownership fell by 4.86 percentage points quarter-over-quarter, with a net change of +7 holders.
The top 10 institutions account for 68.8% of all reported 13F value in MNPR, and the top 25 account for 91.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Monopar Therapeutics Inc. (MNPR) Institutional Ownership