Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in NBIX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 13.4M | $1.76B | +4.3% | 13.337% | 0.03% |
| 2 | DODGE & COX | 5.5M | $719.4M | -0.9% | 5.441% | 0.40% |
| 3 | AQR CAPITAL MANAGEMENT LLC | 4.9M | $650.7M | +51.0% | 4.921% | 0.30% |
| 4 | VANGUARD PORTFOLIO MANAGEMENT LLC | 4.7M | $622.6M | — | 4.709% | 0.03% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 4.5M | $594.4M | — | 4.496% | 0.01% |
| 6 | STATE STREET CORP | 4.4M | $573.7M | +2.6% | 4.339% | 0.02% |
| 7 | TWO SIGMA INVESTMENTS, LP | 3.1M | $403.2M | +210.8% | 3.050% | 0.33% |
| 8 | RENAISSANCE TECHNOLOGIES LLC | 2.4M | $318.7M | +8.0% | 2.410% | 0.50% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 2.1M | $280.8M | +3.8% | 2.129% | 0.02% |
| 10 | BNP Paribas Asset Management Holding S.A. | 1.5M | $196.8M | +7.0% | 1.488% | 0.23% |
| 11 | WELLINGTON MANAGEMENT GROUP LLP | 1.4M | $183.1M | -20.3% | 1.385% | 0.03% |
| 12 | Vestal Point Capital, LP | 1.3M | $164.7M | — | 1.246% | 4.60% |
| 13 | MILLENNIUM MANAGEMENT LLC | 1.2M | $164.3M | +181.7% | 1.243% | 0.11% |
| 14 | NORTHERN TRUST CORP | 1.2M | $163.7M | +1.8% | 1.238% | 0.02% |
| 15 | UBS Group AG | 1.2M | $160.9M | +24.1% | 1.217% | 0.02% |
| 16 | MORGAN STANLEY | 1.2M | $160.6M | +0.8% | 1.215% | 0.01% |
| 17 | RTW INVESTMENTS, LP | 1.1M | $139.9M | 0.0% | 1.058% | 1.39% |
| 18 | FIRST TRUST ADVISORS LP | 959K | $126.4M | +97.0% | 0.956% | 0.09% |
| 19 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 903K | $118.9M | +6.1% | 0.899% | 0.02% |
| 20 | IEQ CAPITAL, LLC | 766K | $100.9M | +2.8% | 0.763% | 0.47% |
| 21 | VICTORY CAPITAL MANAGEMENT INC | 732K | $96.4M | +487.4% | 0.729% | 0.06% |
| 22 | ARMISTICE CAPITAL, LLC | 724K | $95.4M | -11.7% | 0.721% | 2.81% |
| 23 | DIMENSIONAL FUND ADVISORS LP | 712K | $93.8M | -0.7% | 0.709% | 0.02% |
| 24 | Bank of New York Mellon Corp | 702K | $92.5M | -4.9% | 0.700% | 0.02% |
| 25 | BRAIDWELL LP | 652K | $85.9M | -13.2% | 0.650% | 2.87% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in NBIX — a direct measure of their conviction.
Filings activity in NBIX during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 681 | 3.9% | 75.38% | 7.55 pp | $12.09B | 9.1% |
| Q4 2025 | 709 | +13% | 82.93% | +3.19 pp | $13.30B | +4.0% |
| Q3 2025 | 626 | +8.9% | 79.74% | +7.40 pp | $12.79B | +10% |
| Q2 2025 | 575 | +1.8% | 72.34% | +11.36 pp | $11.60B | +19% |
| Q1 2025 | 565 | 2.4% | 60.98% | 12.61 pp | $9.78B | 17% |
| Q4 2024 | 579 | +6.0% | 73.59% | +11.77 pp | $11.80B | +19% |
| Q3 2024 | 546 | 4.7% | 61.82% | 38.14 pp | $9.91B | 38% |
| Q2 2024 | 573 | — | 99.96% | — | $16.03B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying NBIX stock.
Based on Q1 2026 13F filings, institutional ownership of Neurocrine Biosciences, Inc. stands at 75.4%, held across 681 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of NBIX, with approximately 13,385,607 shares worth $1.76B as of Q1 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of NBIX, including TWO SIGMA INVESTMENTS, LP, RENAISSANCE TECHNOLOGIES LLC, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for NBIX is 41 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
93 institutions opened new positions in NBIX during Q1 2026, while 121 fully exited. 188 added to existing positions and 397 trimmed.
NBIX institutional ownership fell by 7.55 percentage points quarter-over-quarter, with a net change of -28 holders.
The top 10 institutions account for 50.7% of all reported 13F value in NBIX, and the top 25 account for 66.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Neurocrine Biosciences, Inc. (NBIX) Institutional Ownership