Free cash flow burn accelerated to -$98.5M in 2026Q2, a 137% increase from -$41.6M in 2024Q2, with operating cash flow of -$96.6M and minimal capex of $1.9M, indicating a research-driven model with no capital returns.
Nurix Therapeutics, Inc. (NRIX) cash flow statement — 8-year operating, investing & financing cash flows
| Metric | TTM | Nov'25 | Nov'24 | Nov'23 | Nov'22 | Nov'21 | Nov'20 | Nov'19 | Nov'18 |
|---|
| Cash from Operations | -293.7M | -249.47M | -172.58M | -81.36M | -159.81M | -84.36M | -80K | 601K | -31.68M |
| Operating CF Margin % | - | -297.05% | -316.38% | -105.69% | -413.72% | -283.58% | -0.45% | 1.93% | -84.58% |
| Operating CF Growth % | -145.82% | -44.55% | -112.11% | 49.09% | -89.42% | -105356.25% | -113.31% | 101.9% | - |
| Net Income | -341.35M | -264.46M | -193.57M | -143.95M | -180.36M | -117.19M | -43.24M | -21.7M | -9.43M |
| Depreciation & Amortization | 17.26M | 18.86M | 16.43M | 13.65M | 10.81M | 6.08M | 2.18M | 2.35M | 2.99M |
| Stock-Based Compensation | 39.65M | 37.97M | 33.93M | 33.67M | 28.13M | 15.8M | 4.3M | 510K | 431K |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -354K |
| Other Non-Cash Items | -24.17M | -10.23M | -10.97M | -4.87M | 636K | 1.83M | 273K | -109K | -6K |
| Working Capital Changes | 14.91M | -31.6M | -18.4M | 20.12M | -19.02M | 9.11M | 36.41M | 19.55M | -25.31M |
| Change in Receivables | 0 | 0 | 0 | 0 | 6M | -6M | -11.35M | 0 | 12.37M |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 6.77M | 0 | 0 | 0 |
| Change in Payables | 6.67M | -630K | 5.21M | 1.61M | 85K | 1.59M | 1.23M | 302K | -519K |
| Cash from Investing | 19.99M | 147.85M | -257.71M | 68.3M | 27.2M | -108.25M | -254.4M | 8.5M | 39.99M |
| Capital Expenditures | -10.82M | -14M | -9.27M | -8.4M | -12.24M | -5.66M | -4.55M | -1.65M | -1.59M |
| CapEx % of Revenue | 29.44% | 16.67% | 17% | 10.91% | 31.7% | 19.03% | 25.55% | 5.31% | 4.26% |
| Acquisitions | 0 | 0 | 0 | 0 | -39.44M | 102.59M | 249.85M | -10.15M | 6K |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 0 | 0 | 39.44M | -102.59M | -249.85M | 10.15M | 0 |
| Cash from Financing | 257.2M | 238.64M | 485.67M | 3.22M | 117.19M | 153.88M | 339.02M | 126K | 529K |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 257.2M | 238.64M | 478.5M | 3.22M | 19.4M | 150.16M | 338.06M | 126K | 529K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | -7K | -16K | -2K |
| Other Financing | 0 | 0 | 7.17M | 0 | 97.79M | 3.73M | 963K | 0 | 0 |
| Net Change in Cash | -16.51M | 137.03M | 55.37M | -9.85M | -15.42M | -38.73M | 84.54M | 9.22M | 8.85M |
| Free Cash Flow | -304.53M | -263.47M | -181.86M | -89.77M | -172.05M | -90.03M | -4.63M | -1.05M | -33.27M |
| FCF Margin % | -828.28% | -313.73% | -333.38% | -116.6% | -445.42% | -302.61% | -26% | -3.37% | -88.84% |
| FCF Growth % | -34.87% | -44.88% | -102.59% | 47.83% | -91.11% | -1843.15% | -341.24% | 96.84% | - |
| FCF per Share | -2.74 | -3.04 | -2.71 | -1.65 | -3.54 | -2.10 | -0.30 | -0.03 | -2.07 |
| FCF Conversion (FCF/Net Income) | 0.89x | 0.94x | 0.89x | 0.57x | 0.89x | 0.72x | 0.00x | -0.03x | 3.36x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 481K | 1K | 1K | 1K |
Quick answers to the most common questions about buying NRIX stock.
Nurix Therapeutics, Inc. (NRIX) generated $-249.5M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Nurix Therapeutics, Inc. (NRIX) reported negative free cash flow of $263.5M in 2025, indicating capital requirements exceeded cash from operations.
Nurix Therapeutics, Inc. (NRIX) spent $14.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
Key Metrics
Top Statement Risk
Dependence on partnership revenue
Metrics are mathematically derived from official filings.
Cash Conversion Distorted by Milestones
Operating cash flow exceeded net loss in 2026Q2 (OCF/NI 1.08), but this ratio swung from 0.66 to 1.45 over the past year, reflecting episodic partnership payments rather than consistent earnings quality.
The OCF/NI ratio has been highly volatile, ranging from 0.66 in 2025Q3 to 1.45 in 2025Q2, indicating that cash generation is not a reliable function of reported losses. In 2026Q2, operating cash outflow of $96.6M was deeper than the net loss of $89.5M, suggesting that non-cash charges like SBC and D&A are not fully offsetting working capital outflows. This implies that reported losses may understate the true cash burn, and investors should monitor the sustainability of cash conversion as partnership milestones become less predictable.
Free Cash Flow Burn Accelerates
Free cash flow deteriorated to -$98.5M in 2026Q2, a 137% increase from -$41.6M in 2024Q2, with FCF margin worsening to -10.9% from -3.4%, indicating accelerating cash consumption relative to revenue.
The FCF deficit has widened consistently over the past ten quarters, with the most recent quarter showing a burn of $98.5M against revenue of only $9.0M. This trend aligns with the prior income statement analysis showing declining revenue and sustained R&D spending above $80M per quarter. The FCF margin has deteriorated from -2.7% in 2024Q1 to -10.9% in 2026Q2, suggesting that the company's cash runway is shortening unless additional financing or partnership inflows materialize.
Minimal Capex Reflects Asset-Light Model
Capital expenditures averaged only $2.6M per quarter over the last ten quarters, representing less than 20% of revenue in most periods, indicating a research-driven model with limited fixed asset investment.
CapEx has remained modest, ranging from $1.0M to $5.1M per quarter, which is typical for a biotech focused on R&D rather than manufacturing. The CapEx/Revenue ratio spiked to 37.8% in 2025Q4 due to a revenue trough, but this is not indicative of a capital-intensive shift. The low capital intensity suggests that the primary cash drain is operating expenses, particularly R&D and SBC, rather than asset replacement or expansion.
Working Capital Swings Signal Milestone Timing
Working capital changes swung from +$16.5M in 2025Q3 to -$32.5M in 2025Q2, reflecting the timing of partnership payments and expense accruals, which adds volatility to quarterly cash flows.
The working capital line has been erratic, with positive contributions in some quarters (e.g., +$16.5M in 2025Q3) and large outflows in others (e.g., -$32.5M in 2025Q2). This pattern suggests that cash flows are heavily influenced by the timing of milestone receipts and R&D-related payables, rather than operational efficiency. Investors should expect continued quarter-to-quarter noise in operating cash flow as the company manages its working capital around episodic partnership events.
No Capital Returns, Cash Reserved for R&D
No dividends or buybacks were paid over the last ten quarters, with the only acquisition-related cash flow being $38.4M in 2024Q3, indicating that all available cash is directed toward research and development.
Capital deployment has been entirely focused on funding internal R&D, with zero distributions to shareholders. The $38.4M acquisition outflow in 2024Q3 suggests a strategic investment, but no subsequent deals have occurred. This is consistent with a pre-commercial biotech that must conserve cash to advance its pipeline, though the lack of returns may pressure the stock if cash burn continues without corresponding value creation.
Cumulative Losses Outpace Cash Burn
Over the last ten quarters, cumulative net losses totaled -$634.7M while operating cash outflow was -$616.7M, a modest divergence that suggests non-cash charges like SBC and D&A are partially offsetting working capital outflows.
The cumulative gap between net income and operating cash flow is relatively small, with operating cash outflow being $18M less than net losses. This indicates that non-cash expenses (SBC and D&A) are being offset by unfavorable working capital changes, which have consumed cash. The near-parity between the two metrics suggests that reported losses are a reasonable proxy for cash consumption, and the company is not generating cash from operations beyond what is reflected in earnings.
What the Cash Flow Statement Obscures
Stock-based compensation of $11.4M in 2026Q2 is a non-cash charge that reduces reported losses but does not consume cash, yet it still represents a real economic cost to shareholders through dilution.
While SBC is added back to operating cash flow, it does not represent a cash outflow, but it does dilute existing shareholders. Over the last ten quarters, cumulative SBC totaled approximately $92.8M, which is a significant economic cost not reflected in operating cash flow. Additionally, the company's reliance on partnership milestones may obscure the underlying cash burn, as these payments are episodic and not sustainable. Investors should consider the dilutive impact of SBC and the potential for future financing needs as the cash burn continues.