Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ORKA held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 7.4M | $364.5M | +2.3% | 19.843% | 0.02% |
| 2 | VR Adviser, LLC | 4.1M | $203.5M | 0.0% | 11.077% | 7.60% |
| 3 | Fairmount Funds Management LLC | 3.7M | $181.7M | 0.0% | 9.894% | 13.13% |
| 4 | BlackRock, Inc. | 3.5M | $173.0M | -0.4% | 9.418% | 0.00% |
| 5 | VIKING GLOBAL INVESTORS LP | 2.7M | $130.8M | 0.0% | 7.121% | 0.37% |
| 6 | Paradigm Biocapital Advisors LP | 2.3M | $113.8M | +35.7% | 6.196% | 2.33% |
| 7 | RTW INVESTMENTS, LP | 2.1M | $101.0M | 0.0% | 5.496% | 1.00% |
| 8 | Deep Track Capital, LP | 2.0M | $99.8M | -5.9% | 5.432% | 2.06% |
| 9 | Remedium Capital Partners, LLC | 1.9M | $92.7M | +21.7% | 5.044% | 28.98% |
| 10 | VANGUARD CAPITAL MANAGEMENT LLC | 1.9M | $91.2M | — | 4.965% | 0.00% |
| 11 | STATE STREET CORP | 1.6M | $79.1M | +16.6% | 4.308% | 0.00% |
| 12 | PERCEPTIVE ADVISORS LLC | 1.4M | $68.4M | -5.5% | 3.726% | 1.35% |
| 13 | Avidity Partners Management LP | 760K | $52.0M | +15.1% | 2.030% | 11.77% |
| 14 | Polar Capital Holdings Plc | 1.0M | $51.4M | +7.1% | 2.797% | 0.18% |
| 15 | CITADEL ADVISORS LLC | 1.0M | $50.0M | +40.3% | 2.720% | 0.02% |
| 16 | FRANKLIN RESOURCES INC | 1.0M | $49.2M | +7.0% | 2.681% | 0.01% |
| 17 | GEODE CAPITAL MANAGEMENT, LLC | 955K | $46.8M | +1.3% | 2.550% | 0.00% |
| 18 | MERCER GLOBAL ADVISORS INC /ADV | 802K | $39.4M | +7.7% | 2.143% | 0.06% |
| 19 | Woodline Partners LP | 575K | $28.2M | +0.1% | 1.535% | 0.11% |
| 20 | Cormorant Asset Management, LP | 533K | $26.2M | 0.0% | 1.424% | 1.31% |
| 21 | Bellevue Group AG | 507K | $24.9M | — | 1.354% | 0.59% |
| 22 | Affinity Asset Advisors, LLC | 500K | $24.5M | -37.7% | 1.334% | 1.43% |
| 23 | Synergy Financial Management, LLC | 476K | $23.4M | +3.8% | 1.272% | 2.48% |
| 24 | SR ONE CAPITAL MANAGEMENT, LP | 430K | $21.1M | 0.0% | 1.149% | 2.31% |
| 25 | Candriam Luxembourg S.C.A. | 411K | $20.2M | +2.6% | 1.098% | 0.10% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in ORKA — a direct measure of their conviction.
Filings activity in ORKA during Q1 2026, grouped by how each filer changed its position.
7 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 180 | +28% | 97.26% | +38.58 pp | $2.55B | +66% |
| Q4 2025 | 141 | +40% | 58.68% | +25.67 pp | $1.54B | +78% |
| Q3 2025 | 101 | +23% | 33.01% | +18.48 pp | $864M | +127% |
| Q2 2025 | 82 | +14% | 14.53% | +2.29 pp | $380M | +19% |
| Q1 2025 | 72 | +7.5% | 12.24% | 9.90 pp | $320M | 45% |
| Q4 2024 | 67 | +60% | 22.14% | 0.68 pp | $579M | 3.0% |
| Q3 2024 | 42 | — | 22.82% | — | $597M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ORKA stock.
Based on Q1 2026 13F filings, institutional ownership of Oruka Therapeutics, Inc. stands at 97.3%, held across 180 reporting institutions.
FMR LLC is the largest reported institutional holder of ORKA, with approximately 7,431,403 shares worth $0.36B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of ORKA, including VIKING GLOBAL INVESTORS LP, CITADEL ADVISORS LLC.
Our composite Smart Money Score for ORKA is 76 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
63 institutions opened new positions in ORKA during Q1 2026, while 24 fully exited. 111 added to existing positions and 6 trimmed.
ORKA institutional ownership rose by 38.58 percentage points quarter-over-quarter, with a net change of +39 holders.
The top 10 institutions account for 61.0% of all reported 13F value in ORKA, and the top 25 account for 84.7%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Oruka Therapeutics, Inc. (ORKA) Institutional Ownership