Last 32 quarters of trend data · Healthcare · Medical - Diagnostics & Research
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -17.89 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 24.95 | 15.80 | 10.72 | 10.59 | 9.97 | 8.44 | 3.72 | 6.27 | 3.19 | 0.68 | 0.97 | 1.32 | 0.81 | 1.34 | 1.71 | 1.37 | 2.29 | 2.16 | 6.05 | 7.73 | 9.62 |
| — | +87.2% | +187.9% | +68.9% | +212.3% | +1143.3% | +285.3% | +375.3% | +295.7% | -49.4% | -43.5% | -3.7% | -64.8% | -37.8% | -71.7% | -82.3% | -76.1% | -83.2% | -51.4% | -51.2% | -0.8% | |
| P/B Ratio | 5.56 | 6.01 | 2.61 | 2.81 | 3.37 | 3.04 | 1.48 | 2.08 | 1.97 | 0.55 | 0.63 | 0.80 | 0.39 | 0.51 | 0.67 | 0.42 | 0.56 | 0.59 | 1.29 | 2.06 | 2.63 |
| — | +97.4% | +76.0% | +35.5% | +71.3% | +457.3% | +136.7% | +158.8% | +405.5% | +7.3% | -6.1% | +91.0% | -30.7% | -14.5% | -48.2% | -79.6% | -78.6% | -81.9% | -56.9% | -68.6% | -30.3% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 22.7% | 21.2% | 1.8% | 11.0% | 13.2% | 27.6% | 35.0% | 27.1% | 34.0% | 35.6% | 28.1% | 26.5% | 19.1% | 28.7% | 25.1% | 13.8% | 16.7% | 23.5% | 28.1% | 38.7% | 36.2% |
| — | -23.3% | -94.8% | -59.6% | -61.2% | -22.3% | +24.3% | +2.4% | +78.3% | +24.0% | +12.2% | +91.3% | +14.3% | +22.3% | -10.7% | -64.2% | -54.0% | -37.7% | -21.0% | +28.5% | +34.6% | |
| Operating Margin | -126.4% | -150.2% | -207.9% | -145.7% | -160.7% | -126.7% | -85.9% | -107.8% | -55.9% | -74.8% | -96.7% | -121.8% | -168.8% | -151.8% | -158.1% | -191.9% | -183.5% | -152.9% | -185.9% | -97.8% | -79.5% |
| — | -18.5% | -142.0% | -35.1% | -187.2% | -69.4% | +11.2% | +11.5% | +66.9% | +50.7% | +38.9% | +36.5% | +8.0% | +0.7% | +14.9% | -96.2% | -130.9% | -121.6% | -210.8% | -47.6% | -63.1% | |
| Net Margin | -116.7% | -141.7% | -194.1% | -137.3% | -149.4% | -116.6% | -76.4% | -97.8% | -152.0% | -56.7% | -66.4% | -135.1% | -159.5% | -143.5% | -152.0% | -185.8% | -178.3% | -151.0% | -185.3% | -97.7% | -79.4% |
| — | -21.6% | -153.9% | -40.4% | +1.8% | -105.6% | -15.1% | +27.6% | +4.7% | +60.5% | +56.3% | +27.3% | +10.6% | +5.0% | +18.0% | -90.2% | -124.6% | -118.9% | -211.9% | -47.7% | -64.8% |
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -35.0% | -12.9% | -11.6% | -11.0% | -12.0% | -10.1% | -7.7% | -8.9% | -28.0% | -11.0% | -10.4% | -18.9% | -17.8% | -13.0% | -13.9% | -13.5% | -10.4% | -10.0% | -9.4% | -6.4% | -5.3% |
| — | -28.4% | -51.6% | -23.9% | +57.3% | +8.3% | +26.0% | +53.1% | -57.6% | +15.2% | +25.5% | -40.4% | -70.2% | -29.7% | -47.3% | -112.3% | -96.4% | -129.6% | -107.0% | +5.1% | +17.3% | |
| ROA | -26.9% | -9.9% | -9.1% | -8.3% | -8.6% | -7.5% | -5.8% | -6.4% | -18.4% | -6.7% | -6.2% | -11.8% | -12.2% | -9.2% | -10.1% | -10.2% | -7.8% | -7.5% | -7.3% | -5.0% | -4.5% |
| — | -31.8% | -57.1% | -28.2% | +53.0% | -12.1% | +6.1% | +45.3% | -50.2% | +26.8% | +39.2% | -15.7% | -56.1% | -23.2% | -39.8% | -102.3% | -75.3% | -94.2% | -87.4% | +6.9% | +7.6% | |
| ROIC | -39.7% | -12.6% | -12.2% | -11.1% | -10.2% | -9.1% | -7.9% | -9.3% | -8.7% | -10.8% | -11.6% | -14.6% | -18.2% | -13.4% | -13.4% | -12.5% | -9.2% | -8.5% | -8.2% | -5.3% | -4.5% |
| — | -39.2% | -54.1% | -19.7% | -16.7% | +16.0% | +32.1% | +36.2% | +52.0% | +19.5% | +13.4% | -16.8% | -97.4% | -57.5% | -63.7% | -134.1% | -105.0% | -92.5% | -57.2% | +41.8% | +50.1% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.15 | 0.16 | 0.15 | 0.15 | 0.24 | 0.22 | 0.21 | 0.22 | 0.27 | 0.42 | 0.39 | 0.37 | 0.31 | 0.28 | 0.26 | 0.22 | 0.20 | 0.22 | 0.21 | 0.19 | 0.18 |
| — | -27.3% | -28.9% | -29.8% | -9.8% | -46.5% | -44.9% | -40.9% | -13.4% | +50.0% | +52.1% | +65.3% | +55.2% | +26.0% | +22.0% | +18.6% | +9.5% | +357.3% | +586.5% | +233.6% | +234.4% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 6.76 | 5.28 | 6.61 | 6.76 | 4.82 | 6.09 | 6.91 | 6.52 | 4.68 | 3.31 | 3.84 | 3.11 | 4.56 | 5.63 | 5.35 | 6.03 | 6.58 | 6.27 | 7.38 | 10.16 | 12.41 |
| — | -13.3% | -4.2% | +3.7% | +3.2% | +83.9% | +79.9% | +109.9% | +2.5% | -41.1% | -28.3% | -48.5% | -30.6% | -10.1% | -27.5% | -40.7% | -47.0% | -39.7% | -23.6% | +87.1% | +99.2% | |
| Quick Ratio | 6.61 | 5.08 | 6.44 | 6.61 | 4.72 | 5.95 | 6.76 | 6.39 | 4.50 | 3.18 | 3.68 | 2.99 | 4.41 | 5.46 | 5.19 | 5.83 | 6.40 | 6.11 | 7.26 | 10.03 | 12.26 |
| — | -14.7% | -4.9% | +3.3% | +4.8% | +87.4% | +83.8% | +114.1% | +2.2% | -41.9% | -29.1% | -48.8% | -31.2% | -10.6% | -28.5% | -41.8% | -47.8% | -40.5% | -24.5% | +87.0% | +99.3% | |
| Interest Coverage | -395.34 | -855.16 | -637.64 | -365.20 | -337.27 | -416.79 | -561.25 | — | -5582.71 | -1421.00 | -1439.11 | -2952.22 | -1937.00 | -612.31 | -608.47 | -659.85 | -587.47 | -549.64 | -477.00 | -341.41 | -293.30 |
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Includes 30+ ratios · 32 years · Updated daily
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Quick answers to the most common questions about buying PSNL stock.
Personalis, Inc.'s current P/E is -17.9x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Personalis, Inc.'s current operating margin is -126.4%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Personalis, Inc.'s business trajectory between earnings reports.