46% buyers of institutions opening or closing positions this quarter
5 more exits than new buyers, ownership fell 20.63 percentage points vs the prior quarter, and 2 well-known fund managers in the top 25.
46% buyers of institutions opening or closing positions this quarter
55.3% institutional ownership
Flagship Pioneering Inc. portfolio allocation
Institutional ownership vs Biotechnology peers
No Form 4 insider transactions on file
Latest positioning in SANA across 13F flow, ownership shift, marquee holders, and holder-count growth.
Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in SANA held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 37.4M | $107.8M | 0.0% | 13.450% | 0.01% |
| 2 | Flagship Pioneering Inc. | 25.0M | $72.0M | 0.0% | 8.984% | 6.20% |
| 3 | BlackRock, Inc. | 14.2M | $41.0M | +0.1% | 5.117% | 0.00% |
| 4 | STATE STREET CORP | 10.5M | $30.3M | +30.8% | 3.787% | 0.00% |
| 5 | CANADA PENSION PLAN INVESTMENT BOARD | 10.2M | $29.4M | -0.2% | 3.673% | 0.02% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 7.4M | $21.4M | β | 2.672% | 0.00% |
| 7 | BAILLIE GIFFORD & CO | 6.6M | $19.0M | 0.0% | 2.375% | 0.02% |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | 4.2M | $12.0M | +1.6% | 1.503% | 0.00% |
| 9 | Marex Group plc | 4.1M | $11.6M | +8.7% | 1.459% | 0.03% |
| 10 | Integral Health Asset Management, LLC | 3.2M | $9.2M | +6.7% | 1.150% | 0.44% |
| 11 | GOLDMAN SACHS GROUP INC | 3.2M | $9.2M | +113.7% | 1.143% | 0.00% |
| 12 | BANK OF AMERICA CORP /DE/ | 2.9M | $8.5M | +148.4% | 1.059% | 0.00% |
| 13 | Alphabet Inc. | 2.8M | $8.1M | 0.0% | 1.011% | 0.20% |
| 14 | VANGUARD PORTFOLIO MANAGEMENT LLC | 1.7M | $4.9M | β | 0.614% | 0.00% |
| 15 | MILLENNIUM MANAGEMENT LLC | 1.6M | $4.6M | +155.3% | 0.572% | 0.00% |
| 16 | NORTHERN TRUST CORP | 1.5M | $4.3M | +5.1% | 0.531% | 0.00% |
| 17 | MORGAN STANLEY | 1.5M | $4.2M | +13.6% | 0.525% | 0.00% |
| 18 | RENAISSANCE TECHNOLOGIES LLC | 1.5M | $4.2M | -14.2% | 0.521% | 0.01% |
| 19 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.4M | $3.9M | -2.4% | 0.491% | 0.00% |
| 20 | UBS Group AG | 1.4M | $3.9M | +14.6% | 0.487% | 0.00% |
| 21 | Woodline Partners LP | 1.3M | $3.8M | +0.0% | 0.474% | 0.01% |
| 22 | TWO SIGMA INVESTMENTS, LP | 1.2M | $3.5M | -24.1% | 0.431% | 0.00% |
| 23 | AQR CAPITAL MANAGEMENT LLC | 1.1M | $3.2M | -0.9% | 0.404% | 0.00% |
| 24 | VANGUARD FIDUCIARY TRUST CO | 1.1M | $3.1M | β | 0.382% | 0.00% |
| 25 | BALYASNY ASSET MANAGEMENT LLC | 1.0M | $3.0M | -38.4% | 0.371% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in SANA β a direct measure of their conviction.
Filings activity in SANA during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 196 | 2.5% | 55.31% | 20.63 pp | $469M | 27% |
| Q4 2025 | 201 | +12% | 75.94% | +7.54 pp | $645M | +11% |
| Q3 2025 | 179 | +15% | 68.40% | +22.57 pp | $581M | +49% |
| Q2 2025 | 156 | 2.5% | 45.83% | +17.64 pp | $389M | +63% |
| Q1 2025 | 160 | 1.2% | 28.19% | 1.18 pp | $239M | 4.0% |
| Q4 2024 | 162 | +6.6% | 29.37% | 138.20 pp | $249M | 82% |
| Q3 2024 | 152 | +4.8% | 167.57% | +75.64 pp | $1.42B | +82% |
| Q2 2024 | 145 | β | 91.93% | β | $780M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
No recent Form 4 insider transactions on file for SANA.
Quick answers to the most common questions about buying SANA stock.
Based on Q1 2026 13F filings, institutional ownership of Sana Biotechnology, Inc. stands at 55.3%, held across 196 reporting institutions.
FMR LLC is the largest reported institutional holder of SANA, with approximately 37,430,284 shares worth $0.11B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of SANA, including RENAISSANCE TECHNOLOGIES LLC, TWO SIGMA INVESTMENTS, LP.
Our composite Smart Money Score for SANA is 42 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
30 institutions opened new positions in SANA during Q1 2026, while 35 fully exited. 28 added to existing positions and 136 trimmed.
SANA institutional ownership fell by 20.63 percentage points quarter-over-quarter, with a net change of β holders.
The top 10 institutions account for 75.4% of all reported 13F value in SANA, and the top 25 account for 90.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.