Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in SLNO held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 5.8M | $193.8M | -28.4% | 11.106% | 0.01% |
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 4.4M | $148.2M | +33.2% | 8.493% | 0.03% |
| 3 | BlackRock, Inc. | 3.7M | $125.3M | -3.3% | 7.181% | 0.00% |
| 4 | STATE STREET CORP | 2.7M | $89.8M | +1.2% | 5.144% | 0.00% |
| 5 | Nantahala Capital Management, LLC | 2.5M | $83.5M | +37.3% | 4.785% | 4.29% |
| 6 | Avoro Capital Advisors LLC | 2.3M | $77.0M | -20.7% | 4.413% | 0.79% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 2.2M | $72.1M | β | 4.131% | 0.00% |
| 8 | Polar Capital Holdings Plc | 1.7M | $56.9M | +49.4% | 3.260% | 0.20% |
| 9 | Caption Management, LLC | 1.6M | $53.2M | β | 3.049% | 0.51% |
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.6M | $52.5M | +83.1% | 3.008% | 0.01% |
| 11 | Khrom Capital Management LLC | 1.5M | $50.6M | β | 2.900% | 4.63% |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 1.2M | $41.4M | +6.4% | 2.374% | 0.00% |
| 13 | Woodline Partners LP | 1.1M | $37.2M | +0.0% | 2.134% | 0.14% |
| 14 | Deep Track Capital, LP | 1.1M | $36.1M | +7.9% | 2.070% | 0.75% |
| 15 | BRAIDWELL LP | 959K | $32.1M | -19.2% | 1.841% | 1.07% |
| 16 | READYSTATE ASSET MANAGEMENT LP | 952K | $31.9M | +8.9% | 1.827% | 1.61% |
| 17 | FRANKLIN RESOURCES INC | 835K | $28.0M | +1.4% | 1.602% | 0.01% |
| 18 | Vestal Point Capital, LP | 730K | $24.4M | β | 1.401% | 0.68% |
| 19 | COMMODORE CAPITAL LP | 652K | $21.8M | -45.6% | 1.252% | 1.26% |
| 20 | MILLENNIUM MANAGEMENT LLC | 627K | $21.0M | β | 1.202% | 0.01% |
| 21 | Hood River Capital Management LLC | 623K | $20.9M | +0.9% | 1.196% | 0.21% |
| 22 | Pictet Asset Management Holding SA | 616K | $20.6M | -1.3% | 1.182% | 0.02% |
| 23 | SCHRODER INVESTMENT MANAGEMENT GROUP | 649K | $19.8M | +44.2% | 1.245% | 0.02% |
| 24 | Catalio Capital Management, LP | 578K | $19.3M | +60.4% | 1.109% | 4.04% |
| 25 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 575K | $19.3M | +43.8% | 1.103% | 3.11% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in SLNO β a direct measure of their conviction.
Filings activity in SLNO during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new SLNO position in Q1 2026
Institutions that fully closed their SLNO position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 222 | 8.6% | 69.37% | 35.56 pp | $1.92B | 34% |
| Q4 2025 | 243 | +5.2% | 104.93% | 46.47 pp | $2.90B | 31% |
| Q3 2025 | 231 | +1.8% | 151.40% | 12.52 pp | $4.18B | 7.6% |
| Q2 2025 | 227 | +9.7% | 163.92% | +27.27 pp | $4.53B | +20% |
| Q1 2025 | 207 | +29% | 136.65% | +53.90 pp | $3.78B | +65% |
| Q4 2024 | 161 | +16% | 82.75% | 1.70 pp | $2.29B | 2.0% |
| Q3 2024 | 139 | +21% | 84.45% | +20.49 pp | $2.33B | +32% |
| Q2 2024 | 115 | β | 63.96% | β | $1.77B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying SLNO stock.
Based on Q1 2026 13F filings, institutional ownership of Soleno Therapeutics, Inc. stands at 69.4%, held across 222 reporting institutions.
FMR LLC is the largest reported institutional holder of SLNO, with approximately 5,788,410 shares worth $0.19B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of SLNO, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for SLNO is 38 out of 100 (Bearish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
50 institutions opened new positions in SLNO during Q1 2026, while 71 fully exited. 34 added to existing positions and 136 trimmed.
SLNO institutional ownership fell by 35.56 percentage points quarter-over-quarter, with a net change of -21 holders.
The top 10 institutions account for 49.7% of all reported 13F value in SLNO, and the top 25 account for 71.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Soleno Therapeutics, Inc. (SLNO) Institutional Ownership