Soleno Therapeutics, Inc. (SLNO) Revenue History
Annual and quarterly revenue from 2012 to present
SLNO Revenue Over Time (2012–2025)
SLNO Revenue Growth History
2 of 4 years with positive growth- FY2012 revenue growth
- N/A
- FY2013 revenue growth
- N/A
- FY2014 revenue growth
- -100.0%
- FY2015 revenue growth
- N/A
- FY2016 revenue growth
- +274.3%
- FY2017 revenue growth
- -107145.4%
- FY2018 revenue growth
- +100.0%
- FY2019 revenue growth
- N/A
- FY2020 revenue growth
- N/A
- FY2021 revenue growth
- N/A
- FY2022 revenue growth
- N/A
- FY2023 revenue growth
- N/A
- FY2024 revenue growth
- N/A
- FY2025 revenue growth
- N/A
| Quarter | Revenue | YoY |
|---|---|---|
| Q1 2026 | $94.6M | — |
| Q4 2025 | $91.7M | — |
| Q3 2025 | $66.0M | — |
| Q2 2025 | $32.7M | — |
| Q1 2025 | $0 | — |
| Q4 2024 | $0 | — |
| Q3 2024 | $0 | — |
| Q2 2024 | $0 | — |
Multi-year avg. share of annual revenue by fiscal quarter
SLNO Revenue Analysis (2012–2025)
Current Revenue & Growth
As of June 22, 2026, Soleno Therapeutics, Inc. (SLNO) generated trailing twelve-month (TTM) revenue of $285.0 million. The most recent quarter (Q1 2026) recorded $94.6 million in revenue, up 3.1% sequentially.
Historical Growth Trajectory
SLNO's historical revenue data shows various trends over time. Soleno Therapeutics, Inc.'s highest annual revenue of $190.4 million was recorded in 2025, an all-time high.
Peer Comparison
Compared to Healthcare sector peers — including RARE (+13.3% YoY), ACAD (+9.9% YoY), and RYTM (+58.7% YoY). Compare SLNO vs RARE →
SLNO Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| SLNOCurrent | $285M | - | - | 7.9% | |
 RARE | $673M | +13.3% | +19.9% | -79.5% | |
 ACAD | $1.1B | +9.9% | +19.4% | 9.8% | |
 RYTM | $190M | +58.7% | - | -101.2% | |
 MDGL | $958M | +256.8% | - | -31.3% | |
 PTCT | $1.7B | -53.3% | +35.4% | 49.5% |
SLNO Historical Revenue Data (2012–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $190.4M | - | $187.7M | 98.6% | $14.9M | 7.9% |
| 2024 | $0 | - | $0 | - | $-187,671,000 | - |
| 2023 | $0 | - | $0 | - | $-41,384,000 | - |
| 2022 | $0 | - | $0 | - | $-24,397,000 | - |
| 2021 | $0 | - | $0 | - | $-31,528,000 | - |
| 2020 | $0 | - | $-2,194,000 | - | $-31,949,000 | - |
| 2019 | $0 | - | $-2,297,000 | - | $-23,197,000 | - |
| 2018 | $0 | +100.0% | $-1,919,000 | - | $-14,301,000 | - |
| 2017 | $-1,553,002,000 | -107145.4% | $-1,554,613,000 | 100.1% | $-12,171,315 | 0.8% |
| 2016 | $1.5M | +274.3% | $-58,518 | -4.0% | $-13,610,115 | -938.1% |
| 2015 | $388K | - | $35K | 9.0% | $-12,159,746 | -3137.6% |
| 2014 | $0 | -100.0% | $0 | - | $-5,159,729 | - |
| 2013 | $3.0M | - | $3.0M | 100.0% | $-846,783 | -28.2% |
| 2012 | $0 | - | $0 | - | $-3,597,106 | - |
Intrinsic Valuation
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Historical Returns
14+ years return with dividends reinvested.
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Peer Comparison
Compare growth, multiples, and margins vs sector.
SLNO — Frequently Asked Questions
Quick answers to the most common questions about buying SLNO stock.
Is SLNO's revenue growth accelerating or slowing?
SLNO TTM revenue: $285M. YoY growth: N/A. 5-year CAGR: N/A.
What is SLNO's revenue history from 2012 to 2026?
Soleno Therapeutics, Inc. (SLNO) revenue history spans 2012 to 2026. TTM revenue as of 2026 is $285M, growing at N/A YoY. The 5-year CAGR is N/A. Complete annual and quarterly revenue figures are available on this page, including gross profit, operating income, and margin trends.
What is SLNO's long-term revenue growth rate (CAGR)?
Soleno Therapeutics, Inc.'s 5-year revenue CAGR of N/A reflects the variable nature of its business expansion. As of 2026, the current YoY growth rate of N/A is in line with this long-term average. CAGR is the most reliable measure of sustained revenue momentum for SLNO.
Why does SLNO's quarterly revenue fluctuate?
SLNO quarterly revenue can fluctuate significantly between periods. A quarter-over-quarter (QoQ) change does not always indicate a trend; comparing the same quarter year-over-year (YoY) is a more reliable signal for underlying growth. Soleno Therapeutics, Inc.'s revenue data from 2012 to 2026 shows full historical quarterly detail on this page.
How is SLNO's revenue distributed by segment?
SLNO reports revenue broken down by product line and geographic region. The segment breakdown on this page shows which business units contribute the most to total revenue as of the latest fiscal year. Concentration in a single segment above 50% indicates category dependence, while a diversified mix signals more resilient revenue streams.
How does SLNO's revenue compare to industry peers?
Soleno Therapeutics, Inc. (SLNO) with TTM revenue of $285M and N/A YoY growth can be benchmarked against sector peers using the comparison table on this page. Revenue growth relative to peers indicates market share gains or losses. The peer section shows TTM revenue, YoY growth, and operating margin for direct comparisons.