Soleno Therapeutics, Inc. (SLNO) Price Target Analysis
Updated Jun 18, 2026
Analyst Rating: Buy
Based on 13 analysts50.9% Below Target
SLNO trades 50.9% below Wall Street's consensus target of $80.00.
Current Price$53.01
Average Target$80.00
Target
Current
Low$53.00
Median$80.00
High$107.00
Analyst Target Range
Forward P/E13.9x
(Value)
PEG Ratio—
Implied Growth+110.6%
(High Growth)
Analyst Spread67.5%
(Wide Disagreement)
Price Forecast (1 Year)
Last 12 months price action with 12-month analyst target path
Consensus Scenario Assumptions
The base valuation assumes SLNO achieves its forward estimates and maintains a stable P/E multiple of 13.9x. This scenario reflects the blended consensus of 13 Wall Street analysts, balancing both positive catalysts and macroeconomic headwinds over the next 12 months.
SLNO Price Target Analysis
Updated June 22, 2026As of June 22, 2026, Soleno Therapeutics, Inc. (SLNO) has a Wall Street consensus price target of $80.00, based on estimates from 13 covering analysts. With the stock currently trading at $53.01, this represents a potential upside of +50.9%. The company has a market capitalization of $2.76B.
Analyst price targets range from a low of $53.00 to a high of $107.00, representing a 68% spread in expectations. The median target of $80.00 aligns closely with the consensus average. The wide target spread reflects significant disagreement on fair value.
The current analyst consensus rating is Buy, with 8 analysts rating the stock as a Buy or Strong Buy,5 rating it Hold, and 0 rating it Sell or Strong Sell. The positive sentiment balance indicates moderate optimism about the stock prospects.
From a valuation perspective, SLNO trades at a trailing P/E of 135.9x and forward P/E of 13.9x. Analysts expect EPS to grow +110.6% over the next year.
Our proprietary valuation model, which blends historical multiples with forward estimates, suggests a base-case price target of $100.42, with bear and bull scenarios of $63.27 and $132.32 respectively. Model confidence stands at 47/100, suggesting limited visibility into future performance.
Investment Context: Price targets represent analyst expectations for the next 12 months and should be considered alongside your own research. Targets are based on analysts' assumptions about earnings growth, margins, and market conditions which may change. For sector-specific context, view other Healthcare stocks.
Analyst Sentiment Comparison
Industry Peer AnalysisAvg Peer Upside
+28.7%
Industry Consensus
Avg Forward P/E
52.1x
(High Premium)
Peers with Coverage
10 / 10
Active Analyst Tracking
| Company | Market Cap | Price | Target | Upside Potential | Rating | Fwd P/E | Analysts |
|---|---|---|---|---|---|---|---|
 RAREUltragenyx Pharmaceutical Inc. | $2.7B | $27.44 | $48.36 | +76.2% | Buy | — | 33 |
 ACADACADIA Pharmaceuticals Inc. | $3.7B | $21.62 | $33.67 | +55.7% | Buy | 55.6x | 37 |
 RYTMRhythm Pharmaceuticals, Inc. | $6.6B | $96.79 | $139.57 | +44.2% | Buy | — | 20 |
 MDGLMadrigal Pharmaceuticals, Inc. | $11.7B | $505.75 | $710.22 | +40.4% | Buy | — | 23 |
 PTCTPTC Therapeutics, Inc. | $6.6B | $78.98 | $95.83 | +21.3% | Buy | 89.1x | 26 |
 ANABAnaptysBio, Inc. | $2.5B | $57.51 | $73.67 | +28.1% | Buy | — | 22 |
 FOLDAmicus Therapeutics, Inc. | $4.5B | $14.49 | $14.50 | +0.1% | Buy | 40.6x | 24 |
 KRYSKrystal Biotech, Inc. | $10.3B | $348.06 | $336.40 | -3.4% | Buy | 44.9x | 17 |
 IMVTImmunovant, Inc. | $7.3B | $35.34 | $45.00 | +27.3% | Buy | — | 23 |
 LGNDLigand Pharmaceuticals Incorporated | $5.5B | $274.88 | $265.33 | -3.5% | Buy | 30.3x | 17 |
SLNO — Frequently Asked Questions
Quick answers to the most common questions about buying SLNO stock.
What is the SLNO stock price target for 2026?
The consensus Wall Street price target for SLNO is $80, representing 50.9% upside from the current price of $53.01. With 13 analysts covering the stock, this strong upside suggests significant value not yet reflected in today's share price.
Is SLNO a buy, sell, or hold?
SLNO has a consensus rating of "Buy" based on 13 Wall Street analysts. The rating breakdown is predominantly bullish, with 8 Buy/Strong Buy ratings. The consensus 12-month price target of $80 implies 50.9% upside from current levels.
Is SLNO stock overvalued or undervalued?
With a forward P/E of 13.9094x, SLNO trades at a relatively low valuation. The consensus target of $80 implies 50.9% appreciation, suggesting meaningful undervaluation.
How high can SLNO stock go?
The most bullish Wall Street analyst has a price target of $107 for SLNO, while the most conservative target is $53. The consensus of $80 represents the median expectation. Our quantitative valuation model projects a bull case target of $132 based on optimistic growth and margin assumptions. These targets typically reflect 12-month expectations.
How many analysts cover SLNO stock?
SLNO is moderately covered, with 13 analysts providing price targets and ratings. Of these, 0 have Strong Buy ratings, 8 have Buy ratings, 5 recommend Hold, and 0 have Sell or Strong Sell ratings. Higher analyst coverage generally indicates greater institutional interest and more reliable consensus estimates.
What is the SLNO stock forecast?
The 12-month SLNO stock forecast based on 13 Wall Street analysts shows a consensus price target of $80, with estimates ranging from $53 (bear case) to $107 (bull case). The median consensus rating is "Buy". Our proprietary valuation model produces a base case fair value of $100, with bear/bull scenarios of $63/$132.
What is SLNO's fair value based on fundamentals?
Our quantitative valuation model calculates SLNO's fair value at $100 (base case), with a bear case of $63 and bull case of $132. The model uses discounted cash flow analysis, historical growth rates, and margin mean-reversion to project FY+2 earnings, then applies an appropriate P/E multiple. The model confidence score is 47/100.
What is SLNO's forward P/E ratio?
SLNO trades at a forward P/E ratio of 13.9x based on next-twelve-months earnings estimates compared to a trailing P/E of 135.9x. The lower forward P/E indicates analysts expect earnings growth. A forward P/E is useful for comparing valuations when earnings are expected to change significantly.
Should I buy SLNO stock?
Wall Street analysts are very optimistic on SLNO, with a "Buy" consensus rating and $80 price target (50.9% upside). 8 of 13 analysts rate it Buy or Strong Buy. This information is for educational purposes only. Always conduct your own research, consider your financial situation, and consult a financial advisor before making investment decisions.
Why do SLNO price targets vary so much?
SLNO analyst price targets range from $53 to $107, a 68% wide spread indicating significant analyst disagreement. Differences stem from varying assumptions about revenue growth, profit margins, competitive dynamics, and valuation multiples. The $80 consensus represents the middle ground. Our model's $63-$132 range provides an independent fundamental perspective.
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