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SNDX logoSyndax Pharmaceuticals, Inc. (SNDX) Earnings History

Annual and quarterly earnings data from 2011 to 2025

TTM Net Income
-$243M
Net Loss
TTM EPS
$-3.29
Diluted
YoY EPS Growth
+11.8%
Strong
Net Margin
-165.6%
Profitability
Operating Margin-158.4%
Gross Margin96.0%
ROE-161.8%
ROA-45.5%
Highest Annual Net Income$25M (2021)
Highest Quarterly EPS$1.81 (Q4 2021)
Consecutive Profitable Years0 years
Q1 2026
Net Income-$43M
EPS$0.00
QoQ Growth+37.3%Excellent

Loading earnings history...

SNDX EPS Growth (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
N/A
N/M
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

SNDX Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
202596.0%-158.4%-165.6%
202496.5%-1434.4%-1346.1%
2023---
2022---
2021100.0%18.8%17.8%
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Syndax Pharmaceuticals, Inc. (SNDX) Earnings Overview

As of May 8, 2026, Syndax Pharmaceuticals, Inc. (SNDX) reported trailing twelve-month net income of -$243M, reflecting +11.8% year-over-year growth. The company earned $-3.29 per diluted share over the past four quarters, with a net profit margin of -165.6%.

Looking at the long-term picture, SNDX's historical earnings data spans multiple years. The company achieved its highest annual net income of $25M in fiscal 2021.

Syndax Pharmaceuticals, Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including KYMR (-$315M net income, -794.4% margin), IMVT (-$464M net income), RVMD (-$1.37B net income), SNDX has outperformed on profitability metrics. Compare SNDX vs KYMR →

SNDX Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
SNDX logoSNDXCurrent
-$243M$-3.29-165.6%-161.8%+11.8%—
KYMR logoKYMR
-$315M$-3.23-794.4%-25.8%-23.8%
IMVT logoIMVT
-$464M$-2.56--62.5%-45.2%
RVMD logoRVMD
-$1.4B$-6.92--58.1%-66.2%
TGTX logoTGTX
$462M$2.8972.6%102.8%+1746.7%
PRAX logoPRAX
-$327M$-11.31--45.8%-32.0%
Best in group
Lowest in group

SNDX Historical Earnings Data (2011–2025)

15 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$285M+10.5%-$273M$-3.29-165.6%-158.4%
2024-$319M-52.3%-$340M$-3.73-1346.1%-1434.4%
2023-$209M-40.2%-$230M$-2.98--
2022-$149M-699.1%-$152M$-2.46--
2021$25M+134.1%$26M$0.4817.8%18.8%
2020-$73M-30.6%-$71M$-1.77-4816.7%-4708.2%
2019-$56M+24.3%-$58M$-1.84-3688.5%-3792.9%
2018-$74M-21.6%-$76M$-2.92-4875.5%-5001.7%
2017-$61M-36.7%-$62M$-2.90-2884.3%-2939.0%
2016-$44M-84.4%-$44M$-3.04-3645.2%-3587.4%

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Compare SNDX vs DBVT

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SNDX — Frequently Asked Questions

Quick answers to the most common questions about buying SNDX stock.

Is SNDX growing earnings?

SNDX EPS stands at $-3.29, with +11.8% growth matching the 5-year CAGR of N/A. TTM net income is $-243M. Earnings trajectory remains consistent.

What are SNDX's profit margins?

Syndax Pharmaceuticals, Inc. net margin is -165.6%, with operating margin at -158.4%. Below-average margins reflect competitive or cost pressures.

How consistent are SNDX's earnings?

SNDX earnings data spans 2011-2025. The current earnings trend is +11.8% YoY. Historical data enables comparison across business cycles.

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SNDX Earnings Over Time (2014–2025)

Net income and EPS trends