Syndax Pharmaceuticals, Inc. (SNDX) Earnings History
Net Loss15 years of earnings data (2011–2025) · Currently unprofitable on a TTM basis
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Syndax Pharmaceuticals, Inc. (SNDX) Earnings Overview
As of June 23, 2026, Syndax Pharmaceuticals, Inc. (SNDX) reported trailing twelve-month net income of -$243M, reflecting +11.8% year-over-year growth. The company earned $-3.29 per diluted share over the past four quarters, with a net profit margin of -165.6%.
Looking at the long-term picture, SNDX's historical earnings data spans multiple years. The company achieved its highest annual net income of $25M in fiscal 2021.
Syndax Pharmaceuticals, Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →
Compared to peers including KYMR (-$315M net income, -794.4% margin), IMVT (-$506M net income), RVMD (-$1.37B net income), SNDX has outperformed on profitability metrics. Compare SNDX vs KYMR →
SNDX Earnings vs Peers
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SNDX Historical Earnings Data (2011–2025)
15 years| Fiscal Year | Net Income | YoY % | Operating Income | EPS (Diluted) | Net Margin | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | -$285M | +10.5% | -$273M | $-3.29 | -165.6% | -158.4% |
| 2024 | -$319M | -52.3% | -$340M | $-3.73 | -1346.1% | -1434.4% |
| 2023 | -$209M | -40.2% | -$230M | $-2.98 | - | - |
| 2022 | -$149M | -699.1% | -$152M | $-2.46 | - | - |
| 2021 | $25M | +134.1% | $26M | $0.48 | 17.8% | 18.8% |
| 2020 | -$73M | -30.6% | -$71M | $-1.77 | -4816.7% | -4708.2% |
| 2019 | -$56M | +24.3% | -$58M | $-1.84 | -3688.5% | -3792.9% |
| 2018 | -$74M | -21.6% | -$76M | $-2.92 | -4875.5% | -5001.7% |
| 2017 | -$61M | -36.7% | -$62M | $-2.90 | -2884.3% | -2939.0% |
| 2016 | -$44M | -84.4% | -$44M | $-3.04 | -3645.2% | -3587.4% |
| 2015 | -$24M | -21.6% | -$21M | $-4.31 | -3846.7% | -3271.6% |
| 2014 | -$20M | -39.9% | -$21M | $-2.07 | - | - |
| 2013 | -$14M | -42.2% | -$9M | $-1.77 | - | - |
| 2012 | -$10M | +23.9% | -$9M | $-0.14 | - | - |
| 2011 | -$13M | - | -$10M | $0.00 | - | - |
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SNDX — Frequently Asked Questions
Quick answers to the most common questions about buying SNDX stock.
What is SNDX earnings per share (EPS)?
SNDX trailing twelve-month (TTM) diluted EPS is $-3.29, reflecting +11.8% year-over-year growth. The 5-year EPS CAGR is N/A. Complete EPS history from 2011 to 2025 is available in the table on this page.
What is Syndax Pharmaceuticals, Inc.'s net income?
Syndax Pharmaceuticals, Inc. (SNDX) trailing twelve-month net income is $-243M as of 2025. Earnings grew +11.8% year-over-year.
Is SNDX profitable?
SNDX is not currently profitable on a TTM basis, reporting a net loss of $-243M. Net margin is -165.6%. Investors should monitor for a return to profitability.
What is SNDX's earnings growth rate?
SNDX compound annual EPS growth rates (CAGR): 1-Year: N/A, 3-Year: N/A, 5-Year: N/A, 10-Year: N/A. These figures measure the annualised rate of diluted EPS growth over each period, based on data from 2011 to 2025.
What are SNDX's profit margins?
Syndax Pharmaceuticals, Inc. net profit margin is -165.6%, operating margin is -158.4%, and gross margin is +96.0%. Below-average margins reflect competitive or cost pressures. Return on Equity is -161.8%.
Is SNDX growing earnings?
SNDX is growing earnings steadily. YoY EPS growth of +11.8% is consistent with the 5-year CAGR of N/A. TTM net income is $-243M.
What was SNDX's best earnings year?
Syndax Pharmaceuticals, Inc.'s highest annual net income on record is $25M, achieved in fiscal year 2021. Earnings history on this page spans 2011 to 2025 and includes all annual and quarterly figures.
What were SNDX's earnings last quarter?
SNDX's most recent reported quarter was Q1 2026. Net income was $-43M with diluted EPS of $0.00. For a full breakdown of all quarters, see the quarterly earnings table on this page.