Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in TRVI held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 13.2M | $246.6M | 0.0% | 9.313% | 15.53% |
| 2 | FMR LLC | 12.6M | $234.3M | +56.3% | 8.848% | 0.01% |
| 3 | BlackRock, Inc. | 11.2M | $208.0M | +8.9% | 7.857% | 0.00% |
| 4 | Frazier Life Sciences Management, L.P. | 9.9M | $185.4M | 0.0% | 7.001% | 4.04% |
| 5 | WELLINGTON MANAGEMENT GROUP LLP | 5.7M | $106.0M | +9.6% | 4.004% | 0.02% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 5.5M | $103.1M | +11.1% | 3.895% | 0.00% |
| 7 | Vivo Capital, LLC | 5.1M | $95.0M | 0.0% | 3.588% | 8.68% |
| 8 | Woodline Partners LP | 4.1M | $76.1M | +307.8% | 2.875% | 0.24% |
| 9 | Vestal Point Capital, LP | 3.1M | $57.8M | +43.1% | 2.183% | 1.35% |
| 10 | MPM BioImpact LLC | 3.1M | $57.3M | -6.8% | 2.165% | 3.50% |
| 11 | FRONTIER CAPITAL MANAGEMENT CO LLC | 3.1M | $57.3M | +54.0% | 2.163% | 0.53% |
| 12 | STATE STREET CORP | 3.0M | $56.5M | +13.6% | 2.132% | 0.00% |
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 2.9M | $54.6M | +5.4% | 2.062% | 0.00% |
| 14 | MARSHALL WACE, LLP | 2.7M | $49.9M | -32.6% | 1.884% | 0.04% |
| 15 | EVENTIDE ASSET MANAGEMENT, LLC | 2.7M | $49.6M | +1.4% | 1.874% | 0.66% |
| 16 | Rubric Capital Management LP | 2.5M | $46.7M | -32.5% | 1.764% | 0.43% |
| 17 | Artia Global Partners LP | 2.2M | $41.2M | +9.8% | 1.557% | 7.61% |
| 18 | ACORN CAPITAL ADVISORS, LLC | 2.1M | $40.0M | 0.0% | 1.511% | 10.92% |
| 19 | First Light Asset Management, LLC | 2.1M | $39.1M | — | 1.477% | 2.38% |
| 20 | Pictet Asset Management Holding SA | 2.0M | $37.6M | +18.0% | 1.418% | 0.04% |
| 21 | Logos Global Management LP | 1.9M | $35.1M | -21.7% | 1.324% | 1.51% |
| 22 | Affinity Asset Advisors, LLC | 1.8M | $33.6M | -10.0% | 1.268% | 1.52% |
| 23 | EMERALD ADVISERS, LLC | 1.8M | $33.5M | -2.3% | 1.266% | 0.79% |
| 24 | Siren, L.L.C. | 1.8M | $33.3M | 0.0% | 1.259% | 0.67% |
| 25 | Pivotal bioVenture Partners Investment Advisor LLC | 1.7M | $32.5M | +12.2% | 1.227% | 10.56% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in TRVI — a direct measure of their conviction.
Filings activity in TRVI during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 220 | +9.5% | 105.95% | +2.81 pp | $2.79B | +71% |
| Q1 2026 | 201 | +9.8% | 103.14% | +3.78 pp | $1.63B | 0.5% |
| Q4 2025 | 183 | +12% | 99.36% | 0.35 pp | $1.64B | +37% |
| Q3 2025 | 164 | +7.2% | 99.71% | 3.36 pp | $1.20B | +93% |
| Q2 2025 | 153 | +11% | 103.07% | +3.83 pp | $619M | +14% |
| Q1 2025 | 138 | +28% | 99.24% | +6.67 pp | $543M | +68% |
| Q4 2024 | 108 | +17% | 92.57% | +52.51 pp | $324M | +72% |
| Q3 2024 | 92 | — | 40.06% | — | $189M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying TRVI stock.
Based on Q2 2026 13F filings, institutional ownership of Trevi Therapeutics, Inc. stands at 106.0%, held across 220 reporting institutions.
NEA Management Company, LLC is the largest reported institutional holder of TRVI, with approximately 13,222,228 shares worth $0.25B as of Q2 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of TRVI.
Our composite Smart Money Score for TRVI is 52 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
36 institutions opened new positions in TRVI during Q2 2026, while 19 fully exited. 158 added to existing positions and 19 trimmed.
TRVI institutional ownership rose by 2.81 percentage points quarter-over-quarter, with a net change of +19 holders.
The top 10 institutions account for 49.2% of all reported 13F value in TRVI, and the top 25 account for 72.2%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.