Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in TWST held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Artisan Partners Limited Partnership | 6.4M | $302.6M | +9.2% | 10.226% | 0.49% |
| 2 | ARK Investment Management LLC | 6.3M | $301.4M | -16.1% | 10.186% | 2.34% |
| 3 | BlackRock, Inc. | 5.6M | $263.9M | -5.8% | 8.920% | 0.00% |
| 4 | EdgePoint Investment Group Inc. | 5.4M | $255.8M | +0.1% | 8.644% | 2.05% |
| 5 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 5.3M | $250.4M | -11.5% | 8.463% | 0.83% |
| 6 | STATE STREET CORP | 3.7M | $174.4M | +1.2% | 5.895% | 0.01% |
| 7 | VANGUARD PORTFOLIO MANAGEMENT LLC | 2.6M | $125.9M | — | 4.254% | 0.01% |
| 8 | VANGUARD CAPITAL MANAGEMENT LLC | 2.6M | $125.4M | — | 4.238% | 0.00% |
| 9 | Invesco Ltd. | 2.2M | $103.2M | +68.3% | 3.488% | 0.02% |
| 10 | FMR LLC | 1.9M | $89.8M | +2641.6% | 3.035% | 0.00% |
| 11 | GOLDMAN SACHS GROUP INC | 1.7M | $81.0M | +0.5% | 2.739% | 0.01% |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 1.5M | $72.2M | +4.1% | 2.441% | 0.00% |
| 13 | Nikko Asset Management Americas, Inc. | 1.5M | $71.1M | -21.4% | 2.403% | 1.01% |
| 14 | Sumitomo Mitsui Trust Holdings, Inc. | 1.5M | $71.1M | -21.4% | 2.403% | 0.05% |
| 15 | FARALLON CAPITAL MANAGEMENT LLC | 1.4M | $67.8M | +18562.1% | 2.293% | 0.44% |
| 16 | CITADEL ADVISORS LLC | 1.3M | $63.2M | — | 2.136% | 0.03% |
| 17 | Soleus Capital Management, L.P. | 1.2M | $58.3M | -34.1% | 1.970% | 2.36% |
| 18 | BAILLIE GIFFORD & CO | 1.2M | $57.7M | -4.8% | 1.951% | 0.06% |
| 19 | First Light Asset Management, LLC | 879K | $41.8M | -23.0% | 1.411% | 3.74% |
| 20 | Tao Capital Management LP | 829K | $39.4M | 0.0% | 1.331% | 33.14% |
| 21 | UBS ASSET MANAGEMENT AMERICAS INC | 824K | $39.2M | -29.8% | 1.323% | 0.01% |
| 22 | DIMENSIONAL FUND ADVISORS LP | 782K | $37.1M | -4.1% | 1.255% | 0.01% |
| 23 | WELLINGTON MANAGEMENT GROUP LLP | 739K | $35.1M | -9.2% | 1.186% | 0.01% |
| 24 | BALYASNY ASSET MANAGEMENT LLC | 726K | $34.5M | +25.4% | 1.166% | 0.12% |
| 25 | NEW YORK STATE COMMON RETIREMENT FUND | 674K | $32.0M | +14.0% | 1.082% | 0.04% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in TWST — a direct measure of their conviction.
Filings activity in TWST during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 277 | +16% | 74.76% | +25.71 pp | $3.55B | +52% |
| Q4 2025 | 238 | +2.6% | 49.05% | +6.14 pp | $2.33B | +14% |
| Q3 2025 | 232 | 2.9% | 42.91% | 10.26 pp | $2.04B | 19% |
| Q2 2025 | 239 | 6.6% | 53.17% | 1.33 pp | $2.52B | 2.4% |
| Q1 2025 | 256 | +4.5% | 54.50% | 6.30 pp | $2.59B | 10% |
| Q4 2024 | 245 | +2.1% | 60.80% | 13.21 pp | $2.88B | 18% |
| Q3 2024 | 240 | 8.4% | 74.01% | +7.71 pp | $3.51B | +12% |
| Q2 2024 | 262 | — | 66.30% | — | $3.14B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying TWST stock.
Based on Q1 2026 13F filings, institutional ownership of Twist Bioscience Corporation stands at 74.8%, held across 277 reporting institutions.
Artisan Partners Limited Partnership is the largest reported institutional holder of TWST, with approximately 6,367,777 shares worth $0.30B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of TWST, including ARK Investment Management LLC, CITADEL ADVISORS LLC.
Our composite Smart Money Score for TWST is 74 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
75 institutions opened new positions in TWST during Q1 2026, while 36 fully exited. 178 added to existing positions and 22 trimmed.
TWST institutional ownership rose by 25.71 percentage points quarter-over-quarter, with a net change of +39 holders.
The top 10 institutions account for 56.2% of all reported 13F value in TWST, and the top 25 account for 78.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Twist Bioscience Corporation (TWST) Institutional Ownership