Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in URGN held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LP | 4.5M | $81.7M | 0.0% | 9.326% | 0.81% |
| 2 | BlackRock, Inc. | 2.8M | $51.2M | +9.4% | 5.840% | 0.00% |
| 3 | TORONTO DOMINION BANK | 2.6M | $47.0M | β | 5.371% | 0.07% |
| 4 | MORGAN STANLEY | 2.6M | $46.0M | -0.1% | 5.254% | 0.00% |
| 5 | Kynam Capital Management, LP | 2.2M | $40.4M | β | 4.613% | 2.52% |
| 6 | Jefferies Financial Group Inc. | 2.2M | $39.5M | 0.0% | 4.515% | 0.27% |
| 7 | Paradigm Biocapital Advisors LP | 1.7M | $30.6M | -61.9% | 3.497% | 0.63% |
| 8 | ACORN CAPITAL ADVISORS, LLC | 1.7M | $30.1M | +15.5% | 3.435% | 8.55% |
| 9 | AMERICAN CENTURY COMPANIES INC | 1.6M | $29.4M | +20.5% | 3.361% | 0.02% |
| 10 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.5M | $27.0M | -13.6% | 3.085% | 3.18% |
| 11 | Opaleye Management Inc. | 1.4M | $25.7M | +432.7% | 2.935% | 3.39% |
| 12 | FRONTIER CAPITAL MANAGEMENT CO LLC | 1.3M | $23.6M | +68.1% | 2.697% | 0.24% |
| 13 | MENORA MIVTACHIM HOLDINGS LTD. | 1.2M | $20.7M | 0.0% | 2.365% | 0.10% |
| 14 | D. E. Shaw & Co., Inc. | 1.0M | $18.4M | +6.3% | 2.100% | 0.02% |
| 15 | J. Goldman & Co LP | 989K | $17.8M | +65.6% | 2.030% | 0.56% |
| 16 | MPM Oncology Impact Management LP | 944K | $17.0M | +0.3% | 1.937% | 1.31% |
| 17 | ORBIMED ADVISORS LLC | 875K | $15.7M | 0.0% | 1.797% | 0.33% |
| 18 | STATE STREET CORP | 874K | $15.7M | +8.3% | 1.794% | 0.00% |
| 19 | Migdal Insurance & Financial Holdings Ltd. | 771K | $13.9M | 0.0% | 1.582% | 0.12% |
| 20 | Soleus Capital Management, L.P. | 727K | $13.1M | +384.7% | 1.492% | 0.53% |
| 21 | GOLDMAN SACHS GROUP INC | 599K | $10.8M | +30.2% | 1.229% | 0.00% |
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 524K | $9.4M | +10.2% | 1.075% | 0.00% |
| 23 | Woodline Partners LP | 501K | $9.0M | 0.0% | 1.028% | 0.03% |
| 24 | Boxer Capital Management, LLC | 500K | $9.0M | 0.0% | 1.026% | 1.18% |
| 25 | VANGUARD PORTFOLIO MANAGEMENT LLC | 410K | $7.4M | β | 0.841% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in URGN β a direct measure of their conviction.
Filings activity in URGN during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new URGN position in Q1 2026
Institutions that fully closed their URGN position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 167 | +1.2% | 55.41% | 10.89 pp | $802M | 16% |
| Q4 2025 | 165 | +5.1% | 66.30% | +8.04 pp | $960M | +14% |
| Q3 2025 | 157 | +6.1% | 58.26% | +21.94 pp | $844M | +60% |
| Q2 2025 | 148 | +5.7% | 36.32% | +6.02 pp | $526M | +20% |
| Q1 2025 | 140 | +1.4% | 30.30% | +5.09 pp | $439M | +20% |
| Q4 2024 | 138 | +7.8% | 25.21% | 4.21 pp | $365M | 14% |
| Q3 2024 | 128 | +11% | 29.42% | 13.43 pp | $426M | 31% |
| Q2 2024 | 115 | β | 42.85% | β | $620M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying URGN stock.
Based on Q1 2026 13F filings, institutional ownership of UroGen Pharma Ltd. stands at 55.4%, held across 167 reporting institutions.
RTW INVESTMENTS, LP is the largest reported institutional holder of URGN, with approximately 4,543,895 shares worth $0.08B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of URGN.
Our composite Smart Money Score for URGN is 27 out of 100 (Bearish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
32 institutions opened new positions in URGN during Q1 2026, while 30 fully exited. 21 added to existing positions and 112 trimmed.
URGN institutional ownership fell by 10.89 percentage points quarter-over-quarter, with a net change of +2 holders.
The top 10 institutions account for 52.7% of all reported 13F value in URGN, and the top 25 account for 81.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
UroGen Pharma Ltd. (URGN) Institutional Ownership