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WVEWave Life Sciences Ltd.
$3.78$727M
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
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P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
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WVE logo

Wave Life Sciences Ltd.

WVE
NASDAQ · Biotechnology
$3.78
At close - Oct 2, 4:00 PM EDT - USD
Market Cap$727M
P/E-3.1x
52W High$21.73
Volume3.74M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Volatile Milestone Revenue Masks Unprofitable Core Operations

Wave Life Sciences presents a high-risk profile, with its financials dominated by extreme revenue volatility from non-recurring licensing events rather than a stable commercial base, as evidenced by quarterly swings from -$7.7M to $83.7M. While the company hol...

GrowthMixed
ProfitabilityWeak
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

WVE price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

4/12 Beats

EPS beat 4 of last 12 quarters

02

Valuation risk

-107% Peers

P/E is 107% below peer median

03

Market leadership

RS 7 · Lag

Laggard (Underperforming 93% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Oct 30

Market performance

Price History →

Trailing total returns as of 10/3/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
WVE-76.30%
S&P 500 (^GSPC)+12.66%
1-Year Return
WVE-46.15%
S&P 500 (^GSPC)+15.01%
3-Year Return
WVE-37.21%
S&P 500 (^GSPC)+76.81%
5-Year Return
WVE-20.59%
S&P 500 (^GSPC)+76.86%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E
-3.1x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-3.1x
N/A
N/A
EV/EBITDA
N/A
N/A
N/A
Price/FCF
N/A
N/A
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$3.98+5.3%
Base (Fair)$5.14-5.0%
Bull$4.62+22.2%
$3.98 Bear$5.14 Base$4.62 Bull
Current Market Price: $3.78
Trades at a 26.5% discount to Base DCF ($5.14)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue
$43M-60.5% YoY
Net income
-$204M-110.7% YoY
Free cash flow
-$187M-23.4% YoY
Operating margin
-504.1%-402.2 pts YoY
ROIC (TTM)-
Avg ROIC 5Y-
ROE (TTM)-55.6%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate4/12 (33%)
Revenue Beat Rate5/12 (42%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Jul 30, 2026
-$0.34-13.4%
vs -$0.30
$2M-69.5%
vs $7M
Q2 2026
Apr 28, 2026
-$0.13+61.8%
vs -$0.34
$38M+352.6%
vs $8M
Q1 2026
Feb 26, 2026
-$0.30-7.1%
vs -$0.28
$17M+7.4%
vs $16M
Q4 2025
Nov 10, 2025
-$0.32-6.7%
vs -$0.30
$8M-53.5%
vs $16M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
GlobeNewsWire·Sep 23, 2026
Wave Life Sciences Initiates Phase 2a Combination Trial of WVE-007 (GalNAc-siRNA) with Tirzepatide for Obesity

WVE-007 induces fat loss without muscle loss, with clinical data supporting 1-2x per year dosing; preclinical data demonstrate Wave's INHBE GalNAc-siRNA in combination with GLP-1 doubled weight loss compared with GLP-1 alone

GlobeNewsWire·Sep 22, 2026
Wave Life Sciences Announces Appointment of Dr. Monika Vnuk as Chief Business Officer

Dr. Vnuk brings substantial business and corporate development leadership experience from Sanofi, Blackstone, and Pfizer CAMBRIDGE, Mass., Sept. 22, 2026 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd.

Defense World·Sep 22, 2026
Comparing WAVE Life Sciences (NASDAQ:WVE) and Septerna (NASDAQ:SEPN)

Septerna (NASDAQ: SEPN - Get Free Report) and WAVE Life Sciences (NASDAQ: WVE - Get Free Report) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their valuation, dividends, risk, institutional ownership, analyst recommendations, earnings and profitability. Analyst Recommendations This is a summary of

Market Watch·Sep 21, 2026
These beaten-down stocks could bounce back in January, if history is any guide

Tax-loss selling is likely to lead these 20 stocks to become artificially depressed in the fourth quarter — and therefore good bets to bounce back in the new year

Filtered for Wave Life Sciences Ltd.More Headlines
04

Compare before deciding

Benchmark WVE against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Wave Life Sciences Ltd. (WVE)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
WVE logoWVEWave Life Sciences Ltd.Current
$3.78$727.28M-3.12-60.55%-478.33%-55.56%—
SRPT logoSRPTSarepta Therapeutics, Inc.
$17.50$1.85B-2.4515.58%-6.93%-9.96%—
IONS logoIONSIonis Pharmaceuticals, Inc.
$43.54$7.24B-18.2933.87%-64.64%-110.84%—
ARWR logoARWRArrowhead Pharmaceuticals, Inc.
$64.19$9.04B-5261.4823258.15%-47.79%-60.05%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$12.26$1.38B-3.2216.92%-672.16%-57.79%—
BEAM logoBEAMBeam Therapeutics Inc.
$24.50$2.52B-30.25120.01%-54.75%-7.7%—

Compare WVE vs Peers

Wave Life Sciences Ltd. (WVE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for WVE.

Scale Benchmark

vs TMO

Larger-name benchmark to compare WVE against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, IONS, ARWR, NTLA

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

WVE SEC Filings & Documents

Wave Life Sciences Ltd. (WVE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jul 30, 2026·SEC

Material company update

Jun 26, 2026·SEC

Material company update

May 18, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 4, 2025·SEC

FY 2024

Mar 6, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Jul 30, 2026·SEC

FY 2026

Apr 28, 2026·SEC

FY 2025

Nov 10, 2025·SEC

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WVE Frequently Asked Questions

Wave Life Sciences Ltd. (WVE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Wave Life Sciences Ltd.'s revenue?

Wave Life Sciences Ltd. (WVE) reported $65.4M in revenue for fiscal year 2025.

How fast is Wave Life Sciences Ltd. growing?

Wave Life Sciences Ltd. (WVE) saw revenue decline by 60.5% over the past year.

Is WVE profitable?

Wave Life Sciences Ltd. (WVE) reported a net loss of $202.5M for fiscal year 2025.

Dividend & Returns
What is WVE's return on equity?

Wave Life Sciences Ltd. (WVE) has a return on equity (ROE) of -55.6%. Negative ROE indicates the company is unprofitable.

What is Wave Life Sciences Ltd.'s free cash flow?

Wave Life Sciences Ltd. (WVE) had negative free cash flow of $186.2M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in WVE back in 2013?

Total return calculator · dividends reinvested · 13+ years of data

See returns →