Xenon Pharmaceuticals Inc. (XENE) Earnings History
Net Loss14 years of earnings data (2012–2025) · Currently unprofitable on a TTM basis
Loading earnings history...
Xenon Pharmaceuticals Inc. (XENE) Earnings Overview
As of September 23, 2026, Xenon Pharmaceuticals Inc. (XENE) reported trailing twelve-month net income of -$409M, reflecting -44.9% year-over-year growth. The company earned $-4.11 per diluted share over the past four quarters, with a net profit margin of -4612.1%.
Looking at the long-term picture, XENE's historical earnings data spans multiple years. The company achieved its highest annual net income of $13M in fiscal 2014.
Xenon Pharmaceuticals Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →
Compared to peers including PRAX (-$339M net income), ACAD ($380M net income, 36.5% margin), PTCT (-$38M net income, 39.4% margin), XENE has comparable earnings metrics. Compare XENE vs PRAX →
XENE Earnings vs Peers
Earnings metrics vs comparable public companies
XENE Historical Earnings Data (2012–2025)
14 years| Fiscal Year | Net Income | YoY % | Operating Income | EPS (Diluted) | Net Margin | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | -$346M | -47.6% | -$373M | $-4.36 | -4612.1% | -4974.3% |
| 2024 | -$234M | -28.5% | -$279M | $-3.01 | - | - |
| 2023 | -$182M | -45.5% | -$214M | $-2.73 | - | - |
| 2022 | -$125M | -58.9% | -$129M | $-2.06 | -1328.9% | -1368.9% |
| 2021 | -$79M | -173.5% | -$79M | $-1.77 | -427.8% | -428.4% |
| 2020 | -$29M | +30.7% | -$31M | $-0.83 | -89.7% | -97.3% |
| 2019 | -$42M | -20.6% | -$43M | $-1.54 | -609.1% | -627.0% |
| 2018 | -$34M | -12.4% | -$38M | $-1.78 | - | - |
| 2017 | -$31M | -33.5% | -$33M | $-1.71 | -9872.7% | -10474.3% |
| 2016 | -$23M | -46.0% | -$25M | $-1.48 | -1275.5% | -1376.4% |
| 2015 | -$16M | -221.0% | -$9M | $-1.10 | -101.1% | -60.1% |
| 2014 | $13M | +8.2% | $11M | $0.94 | 45.9% | 39.1% |
| 2013 | $12M | +379.7% | $10M | $0.39 | 44.0% | 35.5% |
| 2012 | -$4M | - | -$3M | $-3.23 | -30.1% | -22.0% |
Download Data
Export XENE earnings history in CSV or JSON format
Free sign-in required to download data
XENE Chart Terminal
Live VCP patterns, Cup & Handle overlays, support/resistance, and AI trade plans.
Live Breakouts Feed
High-probability breakout stocks crossing their pivot across 5 pattern engines.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
14+ years return with dividends reinvested.
Peer Comparison
Compare growth, multiples, and margins vs sector.
XENE — Frequently Asked Questions
Quick answers to the most common questions about buying XENE stock.
What is XENE earnings per share (EPS)?
XENE trailing twelve-month (TTM) diluted EPS is $-4.11, reflecting -44.9% year-over-year growth. The 5-year EPS CAGR is N/A. Complete EPS history from 2012 to 2025 is available in the table on this page.
What is Xenon Pharmaceuticals Inc.'s net income?
Xenon Pharmaceuticals Inc. (XENE) trailing twelve-month net income is $-409M as of 2025. Earnings declined -44.9% year-over-year.
Is XENE profitable?
XENE is not currently profitable on a TTM basis, reporting a net loss of $-409M. Net margin is -4612.1%. Investors should monitor for a return to profitability.
What is XENE's earnings growth rate?
XENE compound annual EPS growth rates (CAGR): 1-Year: N/A, 3-Year: N/A, 5-Year: N/A, 10-Year: N/A. These figures measure the annualised rate of diluted EPS growth over each period, based on data from 2012 to 2025.
What are XENE's profit margins?
Xenon Pharmaceuticals Inc. net profit margin is -4612.1%, operating margin is -4974.3%, and gross margin is +66.1%. Below-average margins reflect competitive or cost pressures. Return on Equity is -51.8%.
Is XENE growing earnings?
XENE earnings are declining — EPS fell -44.9% year-over-year. TTM net income dropped to $-409M. This contrasts with the 5-year CAGR of N/A.
What was XENE's best earnings year?
Xenon Pharmaceuticals Inc.'s highest annual net income on record is $13M, achieved in fiscal year 2014. Earnings history on this page spans 2012 to 2025 and includes all annual and quarterly figures.
What were XENE's earnings last quarter?
XENE's most recent reported quarter was Q2 2026. Net income was $-111M with diluted EPS of $-1.11. For a full breakdown of all quarters, see the quarterly earnings table on this page.