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XENE logoXenon Pharmaceuticals Inc. (XENE) Earnings History

Annual and quarterly earnings data from 2012 to 2025

TTM Net Income
-$383M
Net Loss
TTM EPS
$-4.39
Diluted
YoY EPS Growth
-44.9%
Declining
Net Margin
-4612.1%
Profitability
Operating Margin-4974.3%
Gross Margin66.1%
ROE-51.8%
ROA-38.9%
Highest Annual Net Income$13M (2014)
Highest Quarterly EPS$0.26 (Q3 2014)
Consecutive Profitable Years0 years
Q1 2026
Net Income-$102M
EPS$-1.17
QoQ Growth+2.8%Solid

Loading earnings history...

XENE EPS Growth (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
N/A
N/M
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

XENE Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
202566.1%-4974.3%-4612.1%
2024---
2023---
2022100.0%-1368.9%-1328.9%
2021100.0%-428.4%-427.8%
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Xenon Pharmaceuticals Inc. (XENE) Earnings Overview

As of May 8, 2026, Xenon Pharmaceuticals Inc. (XENE) reported trailing twelve-month net income of -$383M, reflecting -44.9% year-over-year growth. The company earned $-4.39 per diluted share over the past four quarters, with a net profit margin of -4612.1%.

Looking at the long-term picture, XENE's historical earnings data spans multiple years. The company achieved its highest annual net income of $13M in fiscal 2014.

Xenon Pharmaceuticals Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including PRAX (-$327M net income), ACAD ($376M net income, 36.5% margin), PTCT (-$187M net income, 39.4% margin), XENE has comparable earnings metrics. Compare XENE vs PRAX →

XENE Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
XENE logoXENECurrent
-$383M$-4.39-4612.1%-51.8%-44.9%—
PRAX logoPRAX
-$327M$-11.31--45.8%-32.0%
ACAD logoACAD
$376M$2.1836.5%39.9%+68.4%
PTCT logoPTCT
-$187M$-2.2639.4%-+264.5%
ARVN logoARVN
-$81M$-1.25-30.8%-16.2%+53.8%
OVID logoOVID
-$17M$-0.21-240.1%-17.5%+35.1%
Best in group
Lowest in group

XENE Historical Earnings Data (2012–2025)

14 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$346M-47.6%-$373M$-4.36-4612.1%-4974.3%
2024-$234M-28.5%-$279M$-3.01--
2023-$182M-45.5%-$214M$-2.73--
2022-$125M-58.9%-$129M$-2.06-1328.9%-1368.9%
2021-$79M-173.5%-$79M$-1.77-427.8%-428.4%
2020-$29M+30.7%-$31M$-0.83-89.7%-97.3%
2019-$42M-20.6%-$43M$-1.54-609.1%-627.0%
2018-$34M-12.4%-$38M$-1.78--
2017-$31M-33.5%-$33M$-1.71-9872.7%-10474.3%
2016-$23M-46.0%-$25M$-1.48-1275.5%-1376.4%

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Compare XENE vs DBVT

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XENE — Frequently Asked Questions

Quick answers to the most common questions about buying XENE stock.

Is XENE growing earnings?

XENE EPS fell to $-4.39, with earnings declining -44.9%. This contrasts with the 5-year CAGR of N/A. TTM net income dropped to $-383M.

What are XENE's profit margins?

Xenon Pharmaceuticals Inc. net margin is -4612.1%, with operating margin at -4974.3%. Below-average margins reflect competitive or cost pressures.

How consistent are XENE's earnings?

XENE earnings data spans 2012-2025. The declining earnings trend is -44.9% YoY. Historical data enables comparison across business cycles.

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XENE Earnings Over Time (2014–2025)

Net income and EPS trends