Zymeworks Inc. (ZYME) Earnings History
Net Loss12 years of earnings data (2014–2025) · Currently unprofitable on a TTM basis
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Zymeworks Inc. (ZYME) Earnings Overview
As of June 22, 2026, Zymeworks Inc. (ZYME) reported trailing twelve-month net income of -$103M, reflecting +33.3% year-over-year growth. The company earned $-1.37 per diluted share over the past four quarters, with a net profit margin of -76.6%.
Looking at the long-term picture, ZYME's historical earnings data spans multiple years. The company achieved its highest annual net income of $124M in fiscal 2022.
Zymeworks Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →
Compared to peers including IMVT (-$506M net income), RCUS (-$369M net income, -142.9% margin), MRUS (-$335M net income, -595.9% margin), ZYME has comparable earnings metrics. Compare ZYME vs IMVT →
ZYME Earnings vs Peers
Earnings metrics vs comparable public companies
ZYME Historical Earnings Data (2014–2025)
12 years| Fiscal Year | Net Income | YoY % | Operating Income | EPS (Diluted) | Net Margin | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | -$81M | +33.9% | -$93M | $-1.08 | -76.6% | -87.3% |
| 2024 | -$123M | -3.4% | -$137M | $-1.62 | -160.8% | -179.7% |
| 2023 | -$119M | -195.4% | -$138M | $-1.72 | -156.1% | -181.6% |
| 2022 | $124M | +158.7% | $131M | $1.90 | 30.1% | 31.6% |
| 2021 | -$212M | -17.3% | -$216M | $-4.61 | -794.0% | -808.2% |
| 2020 | -$181M | -24.1% | -$187M | $-3.58 | -463.5% | -481.3% |
| 2019 | -$145M | -297.8% | -$151M | $-3.83 | -492.3% | -512.1% |
| 2018 | -$37M | -251.3% | -$33M | $-1.26 | -68.9% | -62.5% |
| 2017 | -$10M | +69.2% | -$9M | $-0.49 | -20.1% | -17.4% |
| 2016 | -$34M | -76.4% | -$38M | $-1.72 | -307.1% | -343.9% |
| 2015 | -$19M | -48.1% | -$20M | $-0.97 | -198.4% | -206.6% |
| 2014 | -$13M | - | -$13M | $-0.65 | -775.0% | -763.4% |
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ZYME — Frequently Asked Questions
Quick answers to the most common questions about buying ZYME stock.
What is ZYME earnings per share (EPS)?
ZYME trailing twelve-month (TTM) diluted EPS is $-1.37, reflecting +33.3% year-over-year growth. The 5-year EPS CAGR is N/A. Complete EPS history from 2014 to 2025 is available in the table on this page.
What is Zymeworks Inc.'s net income?
Zymeworks Inc. (ZYME) trailing twelve-month net income is $-103M as of 2025. Earnings grew +33.3% year-over-year.
Is ZYME profitable?
ZYME is not currently profitable on a TTM basis, reporting a net loss of $-103M. Net margin is -76.6%. Investors should monitor for a return to profitability.
What is ZYME's earnings growth rate?
ZYME compound annual EPS growth rates (CAGR): 1-Year: N/A, 3-Year: N/A, 5-Year: N/A, 10-Year: N/A. These figures measure the annualised rate of diluted EPS growth over each period, based on data from 2014 to 2025.
What are ZYME's profit margins?
Zymeworks Inc. net profit margin is -76.6%, operating margin is -87.3%, and gross margin is +100.0%. Below-average margins reflect competitive or cost pressures. Return on Equity is -26.7%.
Is ZYME growing earnings?
Yes, ZYME earnings are accelerating — EPS growth of +33.3% exceeds the 5-year CAGR of N/A. TTM net income reached $-103M. Earnings momentum is strengthening.
What was ZYME's best earnings year?
Zymeworks Inc.'s highest annual net income on record is $124M, achieved in fiscal year 2022. Earnings history on this page spans 2014 to 2025 and includes all annual and quarterly figures.
What were ZYME's earnings last quarter?
ZYME's most recent reported quarter was Q1 2026. Net income was $-44M with diluted EPS of $-0.59. For a full breakdown of all quarters, see the quarterly earnings table on this page.