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ZYME logoZymeworks Inc. (ZYME) Earnings History

Annual and quarterly earnings data from 2014 to 2025

TTM Net Income
-$44.22B
Net Loss
TTM EPS
$-592.01
Diluted
YoY EPS Growth
+33.3%
Excellent
Net Margin
-76.6%
Profitability
Operating Margin-87.3%
Gross Margin89.8%
ROE-26.7%
ROA-20.0%
Highest Annual Net Income$124M (2022)
Highest Quarterly EPS$4.65 (Q4 2022)
Consecutive Profitable Years0 years
Q1 2026
Net Income-$44.16B
EPS$-0.59
QoQ Growth-107065.9%Declining

Loading earnings history...

ZYME EPS Growth (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
N/A
N/M
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

ZYME Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
202589.8%-87.3%-76.6%
2024100.0%-179.7%-160.8%
2023-88.1%-181.6%-156.1%
2022100.0%31.6%30.1%
2021100.0%-808.2%-794.0%
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Zymeworks Inc. (ZYME) Earnings Overview

As of May 8, 2026, Zymeworks Inc. (ZYME) reported trailing twelve-month net income of -$44.22B, reflecting +33.3% year-over-year growth. The company earned $-592.01 per diluted share over the past four quarters, with a net profit margin of -76.6%.

Looking at the long-term picture, ZYME's historical earnings data spans multiple years. The company achieved its highest annual net income of $124M in fiscal 2022.

Zymeworks Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including IMVT (-$464M net income), RCUS (-$369M net income, -142.9% margin), MRUS (-$335M net income, -595.9% margin), ZYME has comparable earnings metrics. Compare ZYME vs IMVT →

ZYME Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
ZYME logoZYMECurrent
-$44.2B$-592.01-76.6%-26.7%+33.3%—
IMVT logoIMVT
-$464M$-2.56--62.5%-45.2%
RCUS logoRCUS
-$369M$-2.94-142.9%-63.3%-4.8%
MRUS logoMRUS
-$335M$-4.43-595.9%-41.4%-11.7%
AGIO logoAGIO
-$423M$-7.19-764.0%-30.2%-161.2%
TPST logoTPST
-$36M$-8.12--182.3%+21.5%
Best in group
Lowest in group

ZYME Historical Earnings Data (2014–2025)

12 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$81M+33.9%-$93M$-1.08-76.6%-87.3%
2024-$123M-3.4%-$137M$-1.62-160.8%-179.7%
2023-$119M-195.4%-$138M$-1.72-156.1%-181.6%
2022$124M+158.7%$131M$1.9030.1%31.6%
2021-$212M-17.3%-$216M$-4.61-794.0%-808.2%
2020-$181M-24.1%-$187M$-3.58-463.5%-481.3%
2019-$145M-297.8%-$151M$-3.83-492.3%-512.1%
2018-$37M-251.3%-$33M$-1.26-68.9%-62.5%
2017-$10M+69.2%-$9M$-0.49-20.1%-17.4%
2016-$34M-76.4%-$38M$-1.72-307.1%-343.9%

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ZYME — Frequently Asked Questions

Quick answers to the most common questions about buying ZYME stock.

Is ZYME growing earnings?

ZYME EPS is $-592.01, with earnings growth accelerating to +33.3%. This exceeds the 5-year CAGR of N/A. TTM net income reached $-44.2B.

What are ZYME's profit margins?

Zymeworks Inc. net margin is -76.6%, with operating margin at -87.3%. Below-average margins reflect competitive or cost pressures.

How consistent are ZYME's earnings?

ZYME earnings data spans 2014-2025. The accelerating earnings trend is +33.3% YoY. Historical data enables comparison across business cycles.

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ZYME Earnings Over Time (2014–2025)

Net income and EPS trends