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Axsome Therapeutics, Inc. (AXSM) Total Return Calculator with Dividends Reinvested

Axsome Therapeutics, Inc.

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The total return for Axsome Therapeutics, Inc. (AXSM) stock is +98.49% over the past 12 months. So far it's up 24.59% this year. The 5-year total return is +295.01%, meaning $10,000 invested in AXSM stock 5 years ago would be worth $39,501 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in AXSM 1 year ago, it would be worth $20,082 today — you'd have gained $10,082.

With Dividends Reinvested$20,082+100.82%

Price Only (No DRIP)$20,082+100.82%

Period2025-05-07 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in AXSM

1Y$19,849+$9,849 (+98.5%)98.5% CAGR

3Y$28,641+$18,641 (+186.4%)42.0% CAGR

5Y$39,501+$29,501 (+295.0%)31.6% CAGR

10Y$195,804+$185,804 (+1858.0%)34.6% CAGR

15Y$254,726+$244,726 (+2447.3%)24.1% CAGR

20Y$254,725+$244,725 (+2447.2%)17.6% CAGR

30Y$254,728+$244,728 (+2447.3%)11.4% CAGR

Axsome Therapeutics, Inc. did not pay dividends during this period. Total return = price return.

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As of 2026-05-07

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	+24.59%	—	+24.59%	—	$12,459
1Y	+98.49%	98.49%	+98.49%	—	$19,849
3Y	+186.41%	42.01%	+186.41%	—	$28,641
5Y	+295.01%	31.62%	+295.01%	—	$39,501
10Y	+1858.04%	34.64%	+1858.04%	—	$195,804
15Y	+2447.26%	24.09%	+2447.26%	—	$254,726
20Y	+2447.25%	17.57%	+2447.25%	—	$254,725
30Y	+2447.28%	11.40%	+2447.28%	—	$254,728

Risk & Highlights

Best Year+3756.72%2019

Worst Year-53.61%2021

Max Drawdown-18.50%2026-01-21 → 2026-03-12 · Recovered 2026-04-30

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-8.28%	-8.28%	—	+0.41%	-8.7pp
2025	+109.16%	+109.16%	—	+16.64%	+92.5pp
2024	+9.80%	+9.80%	—	+24.00%	-14.2pp
2023	+8.55%	+8.55%	—	+24.81%	-16.3pp
2022	+103.89%	+103.89%	—	-19.95%	+123.8pp

AXSM outperformed the S&P 500 by 67.17pp over the past year (+98.49% vs +31.32%).

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AXSM Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
AXSMAxsome Therapeutics, Inc.	$11.5B	+31.2%	+24.6%	+98.5%	—	+186.4%	+295.0%	+1858.0%
INVAInnoviva, Inc.	$1.9B	-2.2%	+13.3%	+20.4%	—	+92.8%	+95.5%	+90.5%
SUPNSupernus Pharmaceuticals, Inc.	$3.0B	+1.8%	+4.0%	+58.6%	—	+39.8%	+75.7%	+240.3%
ACADACADIA Pharmaceuticals Inc.	$3.7B	-3.8%	-17.9%	+47.7%	—	-0.3%	+2.5%	-22.3%
INTRInter & Co, Inc.	$2.5B	-0.9%	-5.9%	+18.2%	+1.7pp	+328.9%	+131.7%	+131.7%
PRAXPraxis Precision Medicines, Inc.	$7.6B	+9.0%	+18.0%	+860.9%	—	+2005.6%	-18.4%	-19.0%
ALKSAlkermes plc	$5.9B	+3.6%	+25.0%	+16.3%	—	+14.3%	+60.5%	-7.7%
JAZZJazz Pharmaceuticals plc	$14.3B	+22.3%	+32.0%	+105.6%	—	+64.8%	+32.2%	+58.3%
NKTRNektar Therapeutics	$1.7B	+13.9%	+96.0%	+783.6%	—	+636.7%	-69.4%	-57.6%
PTCTPTC Therapeutics, Inc.	$5.5B	-3.3%	-13.2%	+84.1%	—	+19.9%	+65.2%	+839.5%
VNDAVanda Pharmaceuticals Inc.	$440M	+6.7%	-9.8%	+70.3%	—	+7.4%	-57.5%	-13.6%

Compare:AXSM vs INVA AXSM vs SUPN AXSM vs ACAD AXSM vs INVA vs SUPN

About AXSM Dividend Returns

Axsome Therapeutics, Inc. (AXSM) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of AXSM over the past year?

Axsome Therapeutics, Inc. (AXSM) delivered a return of 98.49% over the past year. Since AXSM does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in AXSM be worth today?

A $10,000 investment in Axsome Therapeutics, Inc. one year ago would be worth $19,849 today, representing a gain of $9,849.

Q3Does AXSM pay dividends?

Axsome Therapeutics, Inc. (AXSM) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For AXSM, the total return equals the price-only return.

Q4Did AXSM beat the S&P 500?

Yes, Axsome Therapeutics, Inc. (AXSM) outperformed the S&P 500 by 67.17 percentage points over the past year. AXSM delivered a total return of 98.49%, compared to the S&P 500's 31.32%. This 67.17pp alpha means investors in AXSM earned more than a passive S&P 500 index fund.

Q5What is AXSM's worst drawdown?

Axsome Therapeutics, Inc. (AXSM) experienced a maximum drawdown of -18.50% over the past year, declining from its peak on 2026-01-21 to its trough on 2026-03-12. The stock recovered to its prior peak by 2026-04-30. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is AXSM's long-term total return over 10, 20, or 30 years?

Here are Axsome Therapeutics, Inc. (AXSM)'s long-term returns with dividends reinvested. Over 10 years, the total return is 1858.0% (34.6% CAGR) — $10,000 would have grown to $195,804. Over 20 years: 2447.2% total return (17.6% CAGR) — $10,000 → $254,725. Over 30 years: 2447.3% total return (11.4% CAGR) — $10,000 → $254,728. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was AXSM's best and worst year?

Axsome Therapeutics, Inc.'s best calendar year was 2019 with a total return of 3756.7%. Its worst year was 2021 with a total return of -53.6%. This range shows the volatility investors should expect — the difference between the best and worst year is 3810.3 percentage points.